Transfer RNA in Protein Synthesis
Transfer RNA in Protein Synthesis

Author: Dolph Hatfield

Publisher: CRC Press

Published: 1992-07-27

Total Pages: 450

ISBN-13: 9780849356988

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Transfer RNA in Protein Synthesis is a comprehensive volume focusing on important aspects of codon usage, selection, and discrimination in the genetic code. The many different functions of tRNA and the specialized roles of the corresponding codewords in protein synthesis from initiation through termination are thoroughly discussed. Variations that occur in the initiation process, in reading the genetic code, and in the selection of codons are discussed in detail. The book also examines the role of modified nucleosides in tRNA interactions, tRNA discrimination in aminoacylation, codon discrimination in translation, and selective use of termination codons. Other topics covered include the adaptation of the tRNA population to codon usage in cells and cellular organelles, the occurence of UGA as a codon for selenocysteine in the universal genetic code, new insights into translational context effects and in codon bias, and the molecular biology of tRNA in retroviruses. The contributions of outstanding molecular biologists engaged in tRNA research and prominent investigators from other scientific disciplines, specifically retroviral research, make Transfer RNA in Protein Synthesis an essential reference work for microbiologists, biochemists, molecular biologists, geneticists, and other researchers involved in protein synthesis research.

Handbook of RNA Biochemistry
Handbook of RNA Biochemistry

Author: Roland K. Hartmann

Publisher: John Wiley & Sons

Published: 2015-06-22

Total Pages: 1370

ISBN-13: 3527327762

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The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.

Cell Biology by the Numbers
Cell Biology by the Numbers

Author: Ron Milo

Publisher: Garland Science

Published: 2015-12-07

Total Pages: 400

ISBN-13: 1317230698

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A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Oligonucleotide Synthesis
Oligonucleotide Synthesis

Author: Piet Herdewijn

Publisher: Springer Science & Business Media

Published: 2008-02-04

Total Pages: 436

ISBN-13: 1592598234

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A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an inhibitor of gene expression.

Chitin in Nature and Technology
Chitin in Nature and Technology

Author: G.W. Gooday

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 562

ISBN-13: 1461321670

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Exegi monumentum ael'e perennius. The monument I have built will last longer than bronze. Horace My previous book, "Chitin", (1977) was listed by the publisher, as a "key research book", among the most requested books by libraries. It received favorable comments from. each of the journals which reviewed it, Science, 198, 28 Oct. 1977, Physiological Entomology, 2(4), Dec. 1977, The Canadian Institute of Food Science and Technology Journal, April 1978, The Quarterly Review of Biology, 53:361, 1978, Oceanographic Abstracts, 15:182, 1979, Annales de Zoologie-Ecologie Animale, 11:127, 1979, and Enzyme & Microbial Technology, 2, 1980. The variety of these journals testifies to the interdisci plinary character of chitin studies. "Chitin" has really been a landmark, to use the definition given by Science, because it stimulated interest in the less known polysaccharides and in modified chitins, besides chitin itself, to the point that three International Conferences on Chitin / Chitosan were convened (Boston, U. S. A. 1977, Sapporo, Japan 1982 and Senigallia, Italy 1985). In convening the 3rd International Conference on Chitin / Chitosan (1-4 April 1985), one of the main objectives was the preparation of the present book. While the proceedings of the previous two Conferences were very valuable, they did not appear in any book catalogs and this severely Ii mi ted their distribution.

RNA Metabolism and Gene Expression in Archaea
RNA Metabolism and Gene Expression in Archaea

Author: Béatrice Clouet-d'Orval

Publisher: Springer

Published: 2017-10-28

Total Pages: 276

ISBN-13: 331965795X

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This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.