RNA Tumor Viruses: Supplements and appendixes
Author:
Publisher:
Published: 1984
Total Pages: 1254
ISBN-13:
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Retroviruses
Author: John M. Coffin
Publisher: CSHL Press
Published: 1997
Total Pages: 856
ISBN-13: 9780879695712
DOWNLOAD EBOOKFor over 25 years the study of retroviruses has underpinned much of what is known about information transfer in cells and the genetic and biochemical mechanisms that underlie cell growth and cancer induction. Emergent diseases such as AIDS and adult T-cell lymphoma have widened even further the community of investigators directly concerned with retroviruses, a development that has highlighted the need for an integrated understanding of their biology and their unique association with host genomes. This remarkable volume satisfies that need. Written by a group of the field's most distinguished investigators, rigorously edited to provide a seamless narrative, and elegantly designed for clarity and readability, this book is an instant classic that demands attention from scientists and physicians studying retroviruses and the disorders in which they play a role.
Human Retroviruses
Author: Bryan Cullen
Publisher: Oxford University Press
Published: 1993
Total Pages: 220
ISBN-13: 9780199633821
DOWNLOAD EBOOKThe first book to specifically cover the molecular biology of retroviruses - of immense importance since the high profile of HIV. International contributors provide detailed reviews of the latest knowledge. An excellent text for both medical and non-medical researchers, it also serves as an illuminating introduction for scientists active in other areas.
Retroviruses
Author: Reinhard Kurth
Publisher: Caister Academic Press Limited
Published: 2010
Total Pages: 0
ISBN-13: 9781904455554
DOWNLOAD EBOOKLeading scientists in the field review the genomics, molecular biology and pathogenesis of these important viruses, comprehensively covering all the recent advances.
HIV-1 Integrase
Author: Nouri Neamati
Publisher: John Wiley & Sons
Published: 2011-08-10
Total Pages: 710
ISBN-13: 1118015363
DOWNLOAD EBOOKThis book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1 integrase.
Retroviral Proteases
Author: Lawrence C. Kuo
Publisher: Gulf Professional Publishing
Published: 1994-09-22
Total Pages: 494
ISBN-13: 9780121821425
DOWNLOAD EBOOKMethods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.
Encyclopedia of AIDS
Author: Thomas J. Hope
Publisher:
Published:
Total Pages:
ISBN-13: 9781461496106
DOWNLOAD EBOOKHuman Retroviruses
Author: Elisa Vicenzi
Publisher:
Published: 2014
Total Pages: 345
ISBN-13: 9781627036702
DOWNLOAD EBOOK"Human Retroviruses: Methods and Protocols collects key experimental protocols that have provided the basis of the major discoveries of the field. Split into five sections, this detailed volume covers mapping of the HIV life cycle, isolation, co-receptor use, and cell tropism of HIV-1, in vivo quantification of HIV-1, biological aspects of HIV-1, as well as HTLVs. Some articles explore assay and function of accessory genes, largely involving the interface between retroviral and host factors, the extracellular role of Tat and Tax, resembling the function of cytokines, and the biotechnological exploitation of HIV as lentiviral vector to carry foreign genes with therapeutic value. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Human Retroviruses: Methods and Protocols provides state-of-art methodological protocols from world leaders in human retrovirology, essential for any lab working this vital field."--Publisher's description.
Retroviruses
Author: Ronald Swanstrom
Publisher: Springer
Published: 2011-12-16
Total Pages: 0
ISBN-13: 9783642752209
DOWNLOAD EBOOKAmong the first diseases for which a viral etiology was esta- blished were tumors, lymphomas, and sarcomas in chickens, shown by Ellermann and Bang (1908) and Rous (1910) to be transmissible with cell-free filtrates. The broad significance of these discoveries was not fully recognized at first, mainly because chickens were perceived as too distanly related to humans to provide useful and relevant models for human disease. Change came slowly. In 1936 Bittner found that a viral agent is involved in the causation of mammary cancer in mice, and in 1957 Gross discovered the first murine leukemia virus. In the years following numerous tumor-inducing viruses, infecting all classes of verte- brates, were isolated. The decisive impulse for the development of the RNA tumor virus field sprang from advances in cell culture. In 1958 Temin and Rubin, following initial observations of Manaker and Groupe, worked out the conditions for virus-induced tumori- genic transformation in cell culture and made this transform- ation the basis for a quantitative assay of viral infectivity and oncogenicity. The genetic and cell biological studies that grew out of Rubin's and Temin's groundwork quickly brought into focus two puzzling problems: a requirement for DNA synthesis early in the lifecycle of the RNA tumor viruses, and the existence of genetic information in the virus that is needed for oncogenesis but not for virus reproduction.
Natural Products Targeting Clinically Relevant Enzymes
Author: Paula B. Andrade
Publisher: John Wiley & Sons
Published: 2017-12-04
Total Pages: 348
ISBN-13: 3527342052
DOWNLOAD EBOOKThe past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.
