Residue evaluation of certain veterinary drugs – Joint FAO/WHO Expert Committee on Food Additives, Ninety-eighth Meeting 20–29 February 2024
Residue evaluation of certain veterinary drugs – Joint FAO/WHO Expert Committee on Food Additives, Ninety-eighth Meeting 20–29 February 2024

Author: World Health Organization

Publisher: World Health Organization

Published: 2024-10-23

Total Pages: 120

ISBN-13: 9240101411

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This volume of FAO JECFA Monographs contains residue evaluation of certain veterinary drugs prepared at the 98th meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held from 20 to 29 February 2024. This JECFA meeting was convened specifically to consider residues of veterinary drugs in food-producing animal species. The tasks for the Committee were to further elaborate principles for evaluating the safety of residues of veterinary drugs in food and for establishing acceptable daily intakes (ADIs) and/or acute reference doses (ARfDs), and to recommend maximum residue limits (MRLs) for substances when they are administered to food-producing animals in accordance with good veterinary practice (GVP) in the use of veterinary drugs. The present volume contains monographs on the evaluations of residue data of substances scheduled for evaluation at the request of the Codex Committee on Residues of Veterinary Drugs in Food. A summary of the recommendations on compounds is also presented in this report. The enclosed monographs provided the scientific basis for the recommendations of MRLs.

Author:

Publisher: Food & Agriculture Org.

Published:

Total Pages: 120

ISBN-13: 9251391262

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Evaluation of certain veterinary drug residues in food: Ninety-eighth report of the Joint FAO/WHO Expert Committee on Food Additives
Evaluation of certain veterinary drug residues in food: Ninety-eighth report of the Joint FAO/WHO Expert Committee on Food Additives

Author: World Health Organization

Publisher: Food & Agriculture Org. [Author] [Author]

Published: 2024-06-17

Total Pages: 114

ISBN-13: 9251387591

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This report represents the conclusions of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) convened to evaluate the safety of veterinary drug residues in food: clopidol, imidacloprid and fumagillin. Annexed to this report is a summary of the Committee’s recommendations on these drugs discussed at the ninety-eighth meeting, including acceptable daily intakes (ADIs), acute reference doses (ARfDs), estimated dietary exposure and proposed maximum residue limits (MRLs). Summaries are also provided for general considerations around the matters of interest arising from previous sessions of the Codex Committee on Residues of Veterinary Drugs in Foods (CCRVDF), update of Guidance for the Safety Evaluation of Residues of Veterinary Drugs with incomplete data packages, and release of JECFA Toolbox for Veterinary Drug Residues Risk Assessment. This volume and others in the WHO Technical Report Series contain infrmation that is useful to those who produce and use veterinary drugs, and those involved with controlling contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities.

Procedural Manual
Procedural Manual

Author: Joint FAO/WHO Codex Alimentarius Commission

Publisher: Food and Agriculture Organization of the United Nations

Published: 2011

Total Pages: 224

ISBN-13:

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The Procedural Manual of the Codex Alimentarius Commission is intended to help Member Governments participate effectively in the work of the joint FAO/WHO Food Standards Programme. The manual is particularly useful for national delegations attending Codex meetings and for international organizations attending as observers. It sets out the basic Rules of Procedure, procedures for the elaboration of Codex standards and related texts, basic definitions and guidelines for the operation of Codex committees. It also gives the membership of the Codex Alimentarius Commission. Also published in French and Spanish.

Evaluation of Certain Veterinary Drug Residues in Food
Evaluation of Certain Veterinary Drug Residues in Food

Author: World Health Organization

Publisher: World Health Organization

Published: 2016-02-22

Total Pages: 128

ISBN-13: 9241209976

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This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA) including MRLs for generic fish species acute reference doses (ARfDs) for veterinary drugs an approach for dietary exposure assessment of compounds used for multiple purposes (i.e. veterinary drugs and pesticides) dietary exposure assessment for less-than-lifetime exposure and the assessment of short-term (90-day and 12-month) studies in dogs. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: two insecticides (diflubenzuron and teflubenzuron) an antiparasitic agent (ivermectin) an ectoparasiticide (sisapronil) and a B2-adrenoceptor agonist (zilpaterol hydrochloride). In addition the Committee considered issues raised in concern forms from the Codex Committee on Residues of Veterinary Drugs in Foods on lasalocid sodium an antiparasitic agent. Annexed to the report is a summary of the Committee's recommendations on these drugs including acceptable daily intakes (ADIs) ARfDs and proposed MRLs.

Risk Management and Food Safety
Risk Management and Food Safety

Author: Food and Agriculture Organization of the United Nations

Publisher: Food & Agriculture Org.

Published: 1997

Total Pages: 40

ISBN-13: 9789251039809

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Risk analysis is widely recognised as the fundamental methodology underlying the development of food safety standards. As recognised in the 1995 consultation, risk analysis is composed of three separate but integrated elements, namely risk assessment, risk management and risk communication. That consultation recognised risk communication as an interactive process of exchange of information and opinion on risk among risk assessors, risk managers, and other interested parties. Risk management is defined within Codex as the process of weighing policy alternatives in the light of the results of risk assessment and, if required, selecting and implementing appropriate control options, including regulatory measures. The outcome of the risk management process, as undertaken by Committees within the Codex Alimentarius system, is the development of standards, guidelines and other recommendations for food safety, m the national situation it is likely that different risk management decisions could be made according to different criteria and different ranges of risk management options. The overall objective of Codex is to ensure consumer protection and to facilitate international trade.

Veterinary Drug Residues
Veterinary Drug Residues

Author: R. J. Heitzman

Publisher: Wiley-Blackwell

Published: 1994

Total Pages: 512

ISBN-13: 9780632037865

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The purpose of this second edition is to bring together the current rapid developments and activities in residues of veterinary drugs within the European Community. The EEC legislation is summarised. There is information on the Reference Laboratories, the Maximum Residues Limits (MRL) and the criteria for the methods to be used for routine analysis of residues by Member States and third countries wishing to export meat to the EC. The current state of examination of residues practised and the analytical methods used in Member States is described in detail. There is a section on quality assurance in the laboratory and also supporting information on residues and chemical/physical data of the most important veterinary drugs

Evaluation of certain veterinary drug residues in food
Evaluation of certain veterinary drug residues in food

Author: World Health Organization

Publisher: Food & Agriculture Org.

Published: 2020-02-13

Total Pages: 130

ISBN-13: 9251321205

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This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including harmonization of residue definition, use of scientific literature in risk assessment, toxicological profiling of compounds and less-than-lifetime dietary exposure assessment, combined exposure to multiple chemicals, and microbiological effects on the safety evaluation of veterinary drug residues in food. Summaries follow the Committee’s evaluations of toxicological and residue data on a variety of veterinary drugs: three insecticides (diflubenzuron, ethion and flumethrin), three antimicrobials (fosfomycin, halquinol and ivermectin) and one antiparasitic agent (selamectin). Annexed to the report is a summary of the Committee’s recommendations on these drugs, including acceptable daily intakes (ADIs) and proposed MRLs.

RESIDUE EVALUATION OF CERTAIN VETERINARY DRUGS
RESIDUE EVALUATION OF CERTAIN VETERINARY DRUGS

Author: Food and Agriculture Organization of the United Nations

Publisher: Food & Agriculture Org.

Published: 2018-10-31

Total Pages: 228

ISBN-13: 9251092109

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In light of growing use of veterinary drugs in animal production systems, this report provides evaluations of eight veterinary drugs found in food, including amoxicillin, ampicillin and ethion. It covers identity of substance, residues in food and metabolism studies.