Evaluation of the Congressionally Directed Medical Research Programs Review Process

Evaluation of the Congressionally Directed Medical Research Programs Review Process

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2016-12-19

Total Pages: 165

ISBN-13: 0309450047

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The medical research landscape in the United States is supported by a variety of organizations that spend billions of dollars in government and private funds each year to seek answers to complex medical and public health problems. The largest government funder is the National Institutes of Health (NIH), followed by the Department of Defense (DoD). Almost half of DoD's medical research funding is administered by the Congressionally Directed Medical Research Programs (CDMRP). The mission of CDMRP is to foster innovative approaches to medical research in response to the needs of its stakeholdersâ€"the U.S. military, their families, the American public, and Congress. CDMRP funds medical research to be performed by other government and nongovernmental organizations, but it does not conduct research itself. The major focus of CDMRP funded research is the improved prevention, diagnosis, and treatment of diseases, injuries, or conditions that affect service members and their families, and the general public. The hallmarks of CDMRP include reviewing applications for research funding using a two-tiered review process, and involving consumers throughout the process. Evaluation of the Congressionally Directed Medical Research Programs Review Process evaluates the CDMRP two-tiered peer review process, its coordination of research priorities with NIH and the Department of Veterans Affairs, and provides recommendations on how the process for reviewing and selecting studies can be improved.


Principles and Practice of Clinical Research

Principles and Practice of Clinical Research

Author: John I. Gallin

Publisher: Elsevier

Published: 2011-04-28

Total Pages: 447

ISBN-13: 0080489567

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The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government


Advancing the Nation's Health Needs

Advancing the Nation's Health Needs

Author: National Research Council

Publisher: National Academies Press

Published: 2005-08-13

Total Pages: 187

ISBN-13: 0309094275

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This report is the twelfth assessment of the National Institutes of Health National Research Service Awards program. The research training needs of the country in basic biomedical, clinical, and behavioral and social sciences are considered. Also included are the training needs of oral health, nursing, and health services research. The report has been broadly constructed to take into account the rapidly evolving national and international health care needs. The past and present are analyzed, and predictions with regard to future needs are presented.


Autoimmune Neurology

Autoimmune Neurology

Author:

Publisher: Elsevier

Published: 2016-03-11

Total Pages: 569

ISBN-13: 0444634460

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Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. - Includes comprehensive coverage of autoimmune neurology - Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders - Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities


Introduction to Research in the Health Sciences - E-Book

Introduction to Research in the Health Sciences - E-Book

Author: Stephen Polgar

Publisher: Elsevier Health Sciences

Published: 2019-08-31

Total Pages: 288

ISBN-13: 0702074926

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Now in its 7th edition this textbook is a must have for any health professional student. It provides a comprehensive overview of health research, in a concise and easy to read format using examples directly related to the health sciences. It helps students understand health research models, and how research goes on to inform and improve evidence-based clinical practice. For practitioners it provides guidance on published research in journals, providing an essential tool to keep their practice evidence based. Uses simple language and demystifies research jargon Covers both quantitative and qualitative research methodology, taking a very practical approach Provides an extensive glossary for better understanding of the language of research Fully updated online interactive self-assessment tests including MCQs, true or false questions and short answer questions.


Beyond the HIPAA Privacy Rule

Beyond the HIPAA Privacy Rule

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2009-03-24

Total Pages: 334

ISBN-13: 0309124999

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In the realm of health care, privacy protections are needed to preserve patients' dignity and prevent possible harms. Ten years ago, to address these concerns as well as set guidelines for ethical health research, Congress called for a set of federal standards now known as the HIPAA Privacy Rule. In its 2009 report, Beyond the HIPAA Privacy Rule: Enhancing Privacy, Improving Health Through Research, the Institute of Medicine's Committee on Health Research and the Privacy of Health Information concludes that the HIPAA Privacy Rule does not protect privacy as well as it should, and that it impedes important health research.


Fundamentals of Clinical Trials

Fundamentals of Clinical Trials

Author: Lawrence M. Friedman

Publisher: Springer Science & Business Media

Published: 1998

Total Pages: 384

ISBN-13: 9780387985862

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This classic reference, now updated with the newest applications and results, addresses the fundamentals of such trials based on sound scientific methodology, statistical principles, and years of accumulated experience by the three authors.


Research Methods in the Health Sciences (First Edition)

Research Methods in the Health Sciences (First Edition)

Author: Deborah Zelizer

Publisher: Cognella Academic Publishing

Published: 2018-12-05

Total Pages:

ISBN-13: 9781516518678

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Research Methods in the Health Sciences provides clinical and non-clinical health science students with a comprehensive review of the designs and methods most frequently used in the discipline. Rather than preparing them to conduct original research, this text helps students develop a broad working knowledge of research processes across methodologies. Over the course of 10 chapters, students gain a strong understanding of the scientific method, evidence-based practice, deductive and inductive reasoning, ethical issues when conducting research, and the role of literature in the research process. They read about developing research problem statements and purpose statements, and asking sound research questions. Dedicated chapters illuminate how to select the right methodologies to ensure a study is valid, reliable, and trustworthy, how to understand qualitative and quantitative studies, and how to understand mixed methods research. Each chapter features field-tested tips for studying the material according to individual learning styles, as well as activities to help students develop high-order thinking skills. Written to help students develop foundational knowledge in the discipline, Research Methods in Health Sciences is an ideal resource for introductory courses in health science research methods.


The Science of Health Disparities Research

The Science of Health Disparities Research

Author: Irene Dankwa-Mullan

Publisher: John Wiley & Sons

Published: 2021-03-16

Total Pages: 548

ISBN-13: 1119374812

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Integrates the various disciplines of the science of health disparities in one comprehensive volume The Science of Health Disparities Research is an indispensable source of up-to-date information on clinical and translational health disparities science. Building upon the advances in health disparities research over the past decade, this authoritative volume informs policies and practices addressing the diseases, disorders, and gaps in health outcomes that are more prevalent in minority populations and socially disadvantaged communities. Contributions by recognized scholars and leaders in the field—featuring contemporary research, conceptual models, and a broad range of scientific perspectives—provide an interdisciplinary approach to reducing inequalities in population health, encouraging community engagement in the research process, and promoting social justice. In-depth chapters help readers better understand the specifics of minority health and health disparities while demonstrating the importance of advancing theory, refining measurement, improving investigative methods, and diversifying scientific research. In 26 chapters, the book examines topics including the etiology of health disparities research, the determinants of population health, research ethics, and research in African American, Asians, Latino, American Indian, and other vulnerable populations. Providing a unified framework on the principles and applications of the science of health disparities research, this important volume: Defines the field of health disparities science and suggests new directions in scholarship and research Explains basic definitions, principles, and concepts for identifying, understanding and addressing health disparities Provides guidance on both conducting health disparities research and translating the results Examines how social, historical and contemporary injustices may influence the health of racial and ethnic minorities Illustrates the increasing national and global importance of addressing health disparities Discusses population health training, capacity-building, and the transdisciplinary tools needed to advance health equity A significant contribution to the field, The Science of Health Disparities Research is an essential resource for students and basic and clinical researchers in genetics, population genetics, and public health, health care policymakers, and epidemiologists, medical students, and clinicians, particularly those working with minority, vulnerable, or underserved populations.


Research Training in Psychiatry Residency

Research Training in Psychiatry Residency

Author: Committee on Incorporating Research into Psychiatry Residency Training.

Publisher: National Academies Press

Published: 2003-12-23

Total Pages: 270

ISBN-13: 0309166896

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The number of psychiatric researchers does not seem to be keeping pace with the needs and opportunities that exist in brain and behavioral medicine. An Institute of Medicine committee conducted a broad review of the state of patient-oriented research training in the context of the psychiatry residency and considered the obstacles to such training and strategies for overcoming those obstacles. Careful consideration was given to the demands of clinical training. The committee concluded that barriers to research training span three categories: regulatory, institutional, and personal factors. Recommendations to address these issues are presented in the committee’s report, including calling for research literacy requirements and research training curricula tailored to psychiatry residency programs of various sizes. The roles of senior investigators and departmental leadership are emphasized in the report, as is the importance of longitudinal training (e.g., from medical school through residency and fellowship). As there appears to be great interest among numerous stakeholders and a need for better tracking data, an overarching recommendation calls for the establishment of a national body to coordinate and evaluate the progress of research training in psychiatry.