Principles and Methods for Assessing Autoimmunity Associated with Exposure to Chemicals

Principles and Methods for Assessing Autoimmunity Associated with Exposure to Chemicals

Author: International Labour Organisation

Publisher: World Health Organization

Published: 2006

Total Pages: 360

ISBN-13: 9241572361

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This document provides an introduction to the field of transgenic mutagenicity assays and assesses the possible role of these assays in toxicology testing and mechanistic research. Part I gives a short overview of in vivo genotoxicity testing. Part II gives an overview of the data produced by various assays. Part III discusses the use of the assays in research. Part IV evaluates the role and potential added value of transgenic mutation assays in toxicology and risk assessment. This document is directed at toxicologists, research scientists and risk assessors.--Publisher's description.