Report of the National Commission on Orphan Diseases
Author: National Commission on Orphan Diseases (U.S.)
Publisher:
Published: 1989
Total Pages: 128
ISBN-13:
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Author: National Commission on Orphan Diseases (U.S.)
Publisher:
Published: 1989
Total Pages: 128
ISBN-13:
DOWNLOAD EBOOKAuthor:
Publisher:
Published: 1989
Total Pages: 106
ISBN-13:
DOWNLOAD EBOOKAuthor: Institute of Medicine
Publisher: National Academies Press
Published: 2011-04-03
Total Pages: 442
ISBN-13: 0309158060
DOWNLOAD EBOOKRare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.
Author: National Commission on Orphan Diseases (U.S.)
Publisher:
Published: 1989
Total Pages: 132
ISBN-13:
DOWNLOAD EBOOKAuthor: United States. Congress. Senate. Committee on Health, Education, Labor, and Pensions
Publisher:
Published: 2001
Total Pages: 14
ISBN-13:
DOWNLOAD EBOOKAuthor: United States. Department of Health, Education, and Welfare
Publisher:
Published: 1972
Total Pages: 64
ISBN-13:
DOWNLOAD EBOOKAuthor: Manuel Posada de la Paz
Publisher: Springer
Published: 2017-12-06
Total Pages: 675
ISBN-13: 3319671448
DOWNLOAD EBOOKThe fields of rare diseases research and orphan products development continue to expand with more products in research and development status. In recent years, the role of the patient advocacy groups has evolved into a research partner with the academic research community and the bio-pharmaceutical industry. Unique approaches to research and development require epidemiological data not previously available to assist in protocol study design and patient recruitment for clinical trials required by regulatory agencies prior to approval for access by patents and practicing physicians.
Author: David Pryde
Publisher: Royal Society of Chemistry
Published: 2014-07-30
Total Pages: 487
ISBN-13: 1782624201
DOWNLOAD EBOOKOrphan drugs are designated drug substances that are intended to treat rare or ‘orphan’ diseases. More than 7000 rare diseases are known that collectively affect some 6-7% of the developed world’s population; however, individually, any single, rare disease may only affect a handful of people making them commercially unattractive for the biopharmaceutical industry to target. Ground breaking legislation, starting with the Orphan Drug Act that was passed in the US in 1983 to provide financial incentives for companies to develop orphan drugs, has sparked ever increasing interest from biopharmaceutical companies to tackle rare diseases. These developments have made rare diseases, and the orphan drugs that treat them, sufficiently attractive to pharmaceutical development and many pharmaceutical companies now have research units dedicated to this area of research. It is therefore timely to review the area of orphan drugs and some of the basic science, drug discovery and regulatory factors that underpin this important, and growing, area of biomedical research. Written by a combination of academic and industry experts working in the field, this text brings together expert authors in the regulatory, drug development, genetics, biochemistry, patient advocacy group, medicinal chemistry and commercial domains to create a unique and timely reference for all biomedical researchers interested in finding out more about orphan drugs and the rare diseases they treat. Providing an up-to-date monograph, this book covers the basic science, drug discovery and regulatory elements behind orphan drugs and will appeal to medicinal and pharmaceutical chemists, biochemists and anyone working within the fields of rare disease research and drug development or pharmaceuticals in industry or academia.
Author: United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research
Publisher:
Published: 1978
Total Pages: 614
ISBN-13:
DOWNLOAD EBOOKAuthor: Tarun Weeramanthri
Publisher: Frontiers Media SA
Published: 2018-06-25
Total Pages: 149
ISBN-13: 2889455017
DOWNLOAD EBOOKPrecision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.