Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology

Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology

Author: Mohammad Resa Nowrousian

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 524

ISBN-13: 3709176581

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Anemia is a frequent complication of cancer and its treatment. A number of clinical studies shows that the impact of anemia is much greater than previously thought. Beyond clinical symptoms, anemia significantly impairs physical and metabolic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. In this book, written by a group of outstanding international experts, the current knowledge on anemia in cancer and its treatment with rhEPO is presented. Future developments are also discussed. Based on a broad spectrum of topics, the book describes the scientific and clinical aspects of anemia in various fields of oncology and gives diagnostic and therapeutic recommendations on when and how to use rhEPO.


Erythropoietins, Erythropoietic Factors, and Erythropoiesis

Erythropoietins, Erythropoietic Factors, and Erythropoiesis

Author: Steven G. Elliott

Publisher: Springer Science & Business Media

Published: 2009-06-05

Total Pages: 337

ISBN-13: 3764386983

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A comprehensive one-source guide to the most current information on red blood cell formation and the action of recombinant human erythropoietins. Topics covered include: erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed. The text is ideal for researchers and clinical investigators in academia, biotechnology, and pharmaceutical companies, as well as clinical research associates, clinical monitors, and physician investigators.


Recombinant Erythropoietin

Recombinant Erythropoietin

Author: OTA. Office of technology assessment

Publisher:

Published: 1990-05-01

Total Pages: 112

ISBN-13: 9780160220623

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OTA was asked to evaluate alternative payment policies that Medicare might use to pay for recombinant erythropoietin. The report idenfied nine options and analyzed their implications across several dimensions: quality of care, access to care, costs and efficiency, equity, technological innovation, and administrative feasibility. Extending coverage to self-administration of the biologic would improve access to care, but would raise expenditures of the Medicare program. Setting payment rates to encourage providers to engage in further research would raise Medicare expenditures in the short term and might merely only transfer research costs from the manufacturers to the Medicare and its beneficiaries. Paying providers according to a fee schedule contains moderate incentives encouraging use, with implications for expenditures and the quality of care. These drawbacks can be adressed, however, by judiciously setting the level of payment and by monitoring use. Of the options for paying the product through competitive bidding is likely to result in the lowest price for Medicare and the lowest expenditures for the program and its beneficiaries.


Erythropoietins and Erythropoiesis

Erythropoietins and Erythropoiesis

Author: Graham Molineux

Publisher: Springer Science & Business Media

Published: 2005-11-17

Total Pages: 294

ISBN-13: 9783764375423

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A comprehensive one-source guide to the most current information on red blood cell formation and the action of recombinant human erythropoietins. Topics covered include: erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed. The text is ideal for researchers and clinical investigators in academia, biotechnology, and pharmaceutical companies, as well as clinical research associates, clinical monitors, and physician investigators. This softcover volume is an unchanged second printing of the hardcover edition published in 2003.


Pathophysiology and Pharmacology of Erythropoietin

Pathophysiology and Pharmacology of Erythropoietin

Author: Horst Pagel

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 318

ISBN-13: 3642770746

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The book contains a series of about 40 articles reflecting the state-of-the-art of the topic "Pathophysiology and Pharmacology of Erythropoietin". Results from both basic research and clinical studies are described in detail. The papers show that the possible therapeutic spectrum of erythropoietin could be expanded considerably when compared with the present situation.


Medical Pharmacology and Therapeutics E-Book

Medical Pharmacology and Therapeutics E-Book

Author: Derek G. Waller

Publisher: Elsevier Health Sciences

Published: 2013-08-07

Total Pages: 741

ISBN-13: 0702055034

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This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice


Textbook of Nephro-Endocrinology

Textbook of Nephro-Endocrinology

Author: Ajay K. Singh

Publisher: Academic Press

Published: 2009-01-12

Total Pages: 534

ISBN-13: 0080920462

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The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. - Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems - Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work - Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field