Raether's Enzyme
Raether's Enzyme

Author: S L Flynn

Publisher:

Published: 2020-10-21

Total Pages: 444

ISBN-13: 9781735183909

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Megan's body hides the secret answer to a million prayers. Now the secret is out and it is her turn to pray. A mysterious substance, Raether's enzyme, has the power to prevent and cure cancer. It is the rarest of genetic gifts. It requires surgery to harvest. Hackers have raided medical databases for the names and addresses of likely donors and published them on the internet. The hunt is on. Megan Bishop looks like easy prey. Young and isolated, she will have to be quick and smart to evade the rogue bounty hunters sent to capture her by a twisted financial genius who seeks to weaponize mercy in his quest for power and vengeance. She will face betrayal and sacrifice. She will find herself at the gates of paranoia as the world closes in on the miracle within her. Her only way out may be to find the wisdom and courage to harness the strange power of Raether's enzyme. Raether's Enzyme is a thriller with a dash of science fiction. It shares a grounded contemporary setting with Neal Stephenson's Reamde. To borrow from Ursula LeGuin, it is a tale of an ambiguous dystopia, where a scientific discovery promises deliverance to the many as it imperils the few. It is a superhero origin story where the mutant power in play offers hope and life.

Duel in the Sun
Duel in the Sun

Author: John Brant

Publisher: Rodale

Published: 2007-03-06

Total Pages: 228

ISBN-13: 1594866287

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Brant re-creates the tense drama of the 1982 Boston Marathon and the powerful forces of fate that drove runners Alberto Salazar and Dick Beardsley in the years afterwards.

Handbook of Surface Plasmon Resonance
Handbook of Surface Plasmon Resonance

Author: Richard B. M. Schasfoort

Publisher: Royal Society of Chemistry

Published: 2017-05-30

Total Pages: 555

ISBN-13: 1782627308

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Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.

Real-Time Analysis of Biomolecular Interactions
Real-Time Analysis of Biomolecular Interactions

Author: K. Nagata

Publisher: Springer Science & Business Media

Published: 2013-12-11

Total Pages: 261

ISBN-13: 4431669701

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The metabolism of all living organisms consists of elaborate and complex interactions among numbers of biomolecules, including protein-protein interactions. BIACORE is a new device that uses surface plasmon resonance for kinetic analysis of molecular interactions and automates whole analytical processes. The number of users of BIACORE is increasing worldwide, but until now nothing had been published in English to explain the principles of this new methodology and the kinds of applications it makes available. This updated and revised version of the Japanese original explains the underlying principles of BIACORE, providing concrete examples that utilize the methodology for analysis in areas ranging from basic to applied sciences. With its generous use of illustrations, this book is a valuable source of information for all users of BIACORE.

Protein-Protein Interactions in Human Disease, Part A
Protein-Protein Interactions in Human Disease, Part A

Author:

Publisher: Academic Press

Published: 2018-02-03

Total Pages: 290

ISBN-13: 0128143452

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Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein interaction network as a means to not only identify the critical proteins involved in the etiology of human diseases, but also identify new protein targets for drug development. Sections cover such topics as protein-protein interaction modulators for epigenetic therapies, intrinsic disorder, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics of occupational diseases, and computational methods in predicting the impact of SNPs in protein-protein network, amongst other topics. - Describes advances in the application of powerful techniques in studying and analyzing protein-protein interactions - Targeted to a wide audience of researchers, specialists and students - Written by authorities in their field - Includes information that is well supported by a number of high quality illustrations, figures and tables

American Trypanosomiasis
American Trypanosomiasis

Author: Jenny Telleria

Publisher: Elsevier

Published: 2010-09-03

Total Pages: 871

ISBN-13: 0123848776

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Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual cost estimated at 20 billion Euros. American Trypanosomiasis provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease: - The host: human and mammalian reservoirs - The insect vectors: domestic and sylvatic vectors - The causative parasite: Trypanosoma cruzi - Informs and updates on all the latest developments in the field - Contributions from leading authorities and industry experts

Protein Interactions
Protein Interactions

Author: Peter Schuck

Publisher: Springer Science & Business Media

Published: 2007-03-20

Total Pages: 537

ISBN-13: 0387359664

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This volume successfully and clearly examines how biophysical approaches can be used to study complex systems of reversibly interacting proteins. It deals with the methodology behind the research and shows how to synergistically incorporate several methodologies for use. Each chapter treats and introduces the reader to different biological systems, includes a brief summary of the physical principles, and mentions practical requirements.

Proteins at Solid-Liquid Interfaces
Proteins at Solid-Liquid Interfaces

Author: Philippe Déjardin

Publisher: Springer Science & Business Media

Published: 2006-09-28

Total Pages: 341

ISBN-13: 3540326588

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This book opens with a description of fundamental aspects of protein adsorption to surfaces, a phenomenon that plays a key role in biotechnological applications, especially at solid-liquid interfaces. Presented here are methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy (OWLS). Also described are sensitive bench techniques for measuring the orientation and structure of proteins at solid-liquid interfaces, including total internal reflection ellipsometry (TIRE), dual polarisation interferometry (DPI) and time of flight - secondary ion mass spectrometry (TOF–SIMS). A model study of fibronectin at polymer surfaces is included, as are studies using microporous membranes and textiles with immobilized enzymes for large-scale applications. Biocompatibility, anti-fouling properties and surface modification to modulate the adsorption and activity of biomolecules are among the other topics addressed in this invaluable book.