Radionuclide Tracer Techniques in Haematology
Radionuclide Tracer Techniques in Haematology

Author: C. S. Bowring

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 149

ISBN-13: 1483182584

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Radionuclide Tracer Techniques in Haematology present an extensive examination of the use of radionuclides in diagnostic medicine and in haematology. It discusses the fundamental structure of radionuclides. It addresses the mechanism of using radionuclides for diagnosis. Some of the topics covered in the book are the analysis of ionization chambers; radionuclide imaging equipment; measurement of red cell and plasma volume; description of Geiger-Muller counter, scintillation counter, and whole body counters; utilization of gamma camera; use of hybrid imaging system . The procedure for blood volume determination is fully covered. An in-depth account of the plasma clearance and plasma iron turnover are provided. The evaluation of iron utilization is completely presented. A chapter is devoted to the use of physiological models and external counting equipment. Another section focuses on the applications of quantitative imaging. The analysis of spleen imaging, bone marrow imaging, and vitamin B12 are briefly covered. The book can provide useful information to radiologists, doctors, students, and researchers.

Isotopes for Medicine and the Life Sciences
Isotopes for Medicine and the Life Sciences

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1995-01-27

Total Pages: 144

ISBN-13: 0309176697

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Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.

Clinical Application of Radiolabelled Platelets
Clinical Application of Radiolabelled Platelets

Author: C. Kessler

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 307

ISBN-13: 9400905815

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AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

Medical Laboratory Haematology
Medical Laboratory Haematology

Author: Roger Hall (FIMLS.)

Publisher: Butterworth-Heinemann

Published: 1991

Total Pages: 760

ISBN-13:

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Revised and updated text (first edition, 1984) covers the normal physiology of the blood, the pathophysiology of hematological disorders, and the principles, techniques, and interpretation of the relevant methods of investigation. This edition gives increased emphasis to the advances in understanding of the physiology of blood, more detailed coverage of hematological disorders, and a revised approach to the disorders of hemostasis. Both a textbook and a bench reference for those already in practice. Annotation copyrighted by Book News, Inc., Portland, OR