This book provides a thorough yet concise introduction to quantitative radiobiology and radiation physics, particularly the practical and medical application. Beginning with a discussion of the basic science of radiobiology, the book explains the fast processes that initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. The final section is presented in a highly practical handbook style and offers application-based discussions in radiation oncology, fractionated radiotherapy, and protracted radiation among others. The text is also supplemented by a Web site.
In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.
This book provides a thorough yet concise introduction to quantitative radiobiology and radiation physics, particularly the practical and medical application. Beginning with a discussion of the basic science of radiobiology, the book explains the fast processes that initiate damage in irradiated tissue and the kinetic patterns in which such damage is expressed at the cellular level. The final section is presented in a highly practical handbook style and offers application-based discussions in radiation oncology, fractionated radiotherapy, and protracted radiation among others. The text is also supplemented by a Web site.
This book is designed to convey as much information as possible in a concise and simple way to make it suitable for students, researchers and clinical medical physicists. Better meanings, codes and examples are included. Most of the basics are also covered for easy reference along with a glossary of objective-type questions. Upon completion of this textbook, the readers will gather knowledge about the physics, chemistry and biology of the human body towards cancer treatment using radiation.
"This tenth edition of Selman's The Fundamentals of Imaging Physics and Radiobiology is the continuation of a seminal work in radiation physics and radiation biology first published by Joseph Selman, MD, in 1954 by Charles C Thomas, Publisher, Ltd., Springfield, IL. Many significant changes have been made in this tenth edition. Color photographs and new illustrations have been provided for several existing chapters and for the new chapters in this book. Revisions and updates have been completed for Chapters 1 through 28, whereas Chapters 29 to 33 are all new. The overall style of Doctor Selman is still present, but, with any revision, the style of the present author is also present. In essence, the author's raison d'être in revising this book was to better reflect current radiology practice and to honor the work of Doctor Selman. Topics discussed in this textbook deal with the physics of x-radiation, the biological interaction of radiation with matter, and all aspects of imaging equipment and technology commonly found in the modern radiology department. The chapter on computed tomography (CT) has been heavily revised and updated. Protective measures regarding radiation safety and radiation hazards for workers and patients are thoroughly discussed and new chapters on dual energy x-ray absorptiometry (DXA), magnetic resonance imaging (MRI), ultrasound (US), fusion and molecular imaging have been added. This book will be very helpful to students about to take the ARRT (R) registry examination, but it is not a registry review book per se. This book also serves as a good overview of radiologic imaging physics for radiographers and other medical professionals"--
The updated Sixth Edition of this popular text will remain the first choice for those who need current, clinically relevant information on how radiation affects the human body. Written by practicing, active radiobiologists, the book brings together basic laboratory research and practical, clinical applications. The easy-to-read text and informative illustrations ensure comprehension, and summaries at the end of each chapter facilitate quick review. The first section covers topics applicable to diagnostic radiology, nuclear medicine, and radiation oncology; the second section offers material specifically for radiation oncologists. This edition includes new material about doses and risks in interventional radiology and cardiology.
The biologic effects of radiation on normal tissues and tumors represent a complex area for investigation. These effects are of far-reaching consequence to the diagnostic radiologist and the radiation oncologist having a significant impact not only in concepts relative to radiation protection but also in concepts relative to tumor biology and its response to radiation injury. The volume edited by SCHERER, STREFFER, and TROTT represents an extension of basic radiation biology data into the effects of radiation in producing pathology in organs and tissues. The data presented by the multiple authors involved in this text cover essentially all tissues in the body with specific definition of radiopathology changes and their impact on clinical care of the patient. This volume represents an important and significant contribution toward a better understanding of these effects and the pathology produced by radiations. L. W. BRADY H.-P. HEILMANN F. HEUCK M. W. DONNER Philadelphia Hamburg Stuttgart Baltimore Preface This book represents an attempt to describe the clinical radiobiology of complications arising in different organs after radiotherapy of cancer patients. Since by their very nature malignant tumors infiltrate the organ in which they have arisen and the neighboring tissues, curative radiotherapy requires the planned irradiation of considerable amounts of healthy but potentially or microscopically involved normal tissues and organs with the full target dose. This may lead to early or late normal tissue radiation injury.
This book presents new information on radiobiology that more clearly refutes the linear no-threshold (LNT) assumption and supports radiation hormesis. Fresh light is cast on the mechanisms of radiation hormesis and the potential benefits of low-dose ionizing radiation in preventing and treating a wide variety of inflammatory and proliferative diseases. It is proposed that these effects may derive from cellular communication via electromagnetic waves directed by DNA, with each cell acting as a quantum computer. Readers will also find close analysis of the negative impacts of radiophobia on many aspects of modern life, including attitudes to imaging technologies, licensing of nuclear power reactors, and preparedness for survival of nuclear war. The book will be of interest to researchers and scientists in radiobiology, radiation protection, health physics, medical physics, and radiology. Specifically, it will provide medical physicians, radiation oncologists, radiation epidemiologists, gerontologists, cell biologists, toxicologists, and nuclear engineers with a wide range of interesting facts and enlightening novel perspectives.
This renowned work is derived from the authors' acclaimed national review course (“Physics of Medical Imaging") at the University of California-Davis for radiology residents. The text is a guide to the fundamental principles of medical imaging physics, radiation protection and radiation biology, with complex topics presented in the clear and concise manner and style for which these authors are known. Coverage includes the production, characteristics and interactions of ionizing radiation used in medical imaging and the imaging modalities in which they are used, including radiography, mammography, fluoroscopy, computed tomography and nuclear medicine. Special attention is paid to optimizing patient dose in each of these modalities. Sections of the book address topics common to all forms of diagnostic imaging, including image quality and medical informatics as well as the non-ionizing medical imaging modalities of MRI and ultrasound. The basic science important to nuclear imaging, including the nature and production of radioactivity, internal dosimetry and radiation detection and measurement, are presented clearly and concisely. Current concepts in the fields of radiation biology and radiation protection relevant to medical imaging, and a number of helpful appendices complete this comprehensive textbook. The text is enhanced by numerous full color charts, tables, images and superb illustrations that reinforce central concepts. The book is ideal for medical imaging professionals, and teachers and students in medical physics and biomedical engineering. Radiology residents will find this text especially useful in bolstering their understanding of imaging physics and related topics prior to board exams.
Supplemented with tables and illustrations throughout, each chapter provides readers with well-delineated descriptions of the different aspects of physics and radiation biology related to nuclear medicine. The last edition was successful and highly acclaimed, as Dr. Saha made many complex concepts readily understandable for residents, students and practitioners in nuclear medicine. This second edition serves as an excellent text for nuclear medicine residents and technology students to prepare for their Board and Registry examinations. Special features include: Statistical tests: The Chi-Square test, the student t-test and linear regression; Internal dosimetry based on uptake variation; Digital computers: Data acquisition, filters, data processing; Coincidence detector gamma camera; Expanded chapter on radiation biology; Criteria for patient release and breast feeding; DOT regulations.
