Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.
Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
New edition of this practical and educational handbook for engineer-designers and other professionals. It describes the electronic technology of the new millennium and the complex physical and engineering problems that occur when such equipment is exposed to radiation. The authors have an accumulated joint combined experience in the field of about 75 years, giving a broader blend of experience than any existing book in the field.
"The new edition of this monograph features renowned experts who offer the most current information and reliable guidance on all aspects of the effects of radiation exposure on humans. They provide the answers you need to effectively treat your patients who have been exposed to accidental, occupational, or medical radiation."--BOOK JACKET.
This open access book summarizes the latest scientific findings regarding the biological effects of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident in 2011. Various cases of changes in animals and organisms have been reported since the FNPP accident. However, it is often unknown whether they are actually due to radiation, since the dose or dose-rate are not necessarily associated with the changes observed. This book brings together the works of radiation biologists and ecologists to provide reliable radioecology data and gives insight into future radioprotection. The book examines the environmental pollution and radiation exposure, and contains valuable data from abandoned livestock in the ex-evacuation zone and from wild animals including invertebrates and vertebrates, aqueous and terrestrial animals, and plants that are subjected to long-term exposure in the area still affected by radiation. It also analyzes dose evaluation, and offers new perspectives gained from the accident, as well as an overview for future studies to promote radioprotection of humans and the ecosystem. Since the biological impact of radiation is influenced by various factors, it is difficult to scientifically define the effects of low-dose/low-dose-rate radiation. However, the detailed research data presented can be combined with the latest scientific and technological advances, such as artificial intelligence, to provide new insights in the future. This book is a unique and valuable resource for researchers, professionals and anyone interested in the impact of exposure to radiation or contamination with radioactive materials.
This wide-ranging book summarizes the current knowledge of radiation defects in semiconductors, outlining the shortcomings of present experimental and modelling techniques and giving an outlook on future developments. It also provides information on the application of sensors in nuclear power plants.
Presenting a monumental achievement: 50 years of data cataloging the immediate, long-term, and hereditary effects of atomic radiation on the survivors of the Hiroshima and Nagasaki bombs. Authored by one of the key members of the Atomic Bomb Casualty Commission founded in 1947, this unique work documents the critical findings and conclusions of the longest ongoing medical study in history; it will surely become the foundation for all future investigations and standards regarding the bioeffects of ionizing radiation. "In my opinion, Dr. Schull has written a very interesting and accurate account of the atomic bomb follow-up program in Japan. He writes extremely well, with areas of his particular scientific interest described in great detail. He also describes events and the social implications in a manner that has broad, general appeal." —Stuart C. Finch, MD University of Medicine and Dentistry of New Jersey "A history of the Hiroshima/Nagasaki study is badly needed. I was very happy to hear that Jack Schull was working on such a project, and it is an understatement to say that I am anxious to see it published." —Seymour Jablon, PhD Bethesda, Maryland "Rarely in the history of a program will one have a nearly 50-year account from an eyewitness and major participant, beginning with the program's onset to the present. Jack's book offers the reader this extraordinary insight into the birth and development of the study of the A-bomb survivors. Moreover, he has served on all major national and international commissions dealing with radiation protection and risk assessment and he interweaves the Japanese studies into the radiation risk issues in a way that few, if any, other contemporary scientists can." —Seymour Abrahamson, PhD Radiation Effects Research Foundation On August 6 and 9, 1945, the only atomic bombs ever used in warfare were dropped on the Japanese cities of Hiroshima and Nagasaki. The destruction and death caused by those bombings presented the world with a vivid portrait of the dangers of the atomic age. However, the thousands of bomb survivors have given scientists a massive, firsthand perspective on the bioeffects of radioactivity. It is the study of these survivors that forms the foundation of the modern understanding of the immediate, long-term, and hereditary consequences of exposure to ionizing radiation. Effects of Atomic Radiation: A Half-Century of Studies from Hiroshima and Nagasaki is the definitive account of the methods, findings, and conclusions of the 50-year study on the survivors of the atomic bomb blasts. It is a truly monumental work, surveying a colossal body of data to offer a comprehensive, unified, and authoritative summary of not only the scientific study itself, but the personal, social, and political factors that have shaped the investigation from its inception. The book goes beyond the simple compilation of facts, giving the reader unique insight into this unprecedented research project and exploring the complex web of subjective perceptions and fears that color popular, national, and even scientific views of radiation exposure in moderate and extreme cases. Authored by Dr. William J. Schull, perhaps the single most influential scientist involved in the studies, this book conveys both his authority and sensitivity. Dr. Schull arrived in Japan in 1949 and was instrumental in the development of the Atomic Bomb Casualty Commission. Since then, he has been one of the driving forces behind the largest medical follow-up study ever undertaken. His years spent working directly with bomb survivors imbue his narrative with a compelling personal history, and his service on numerous national and international committees studying ionizing radiation give him a broad, authoritative perspective on the implications of the ABCC's work. Effects of Atomic Radiation: A Half-Century of Studies from Hiroshima and Nagasaki is first and foremost a scientific work, summarizing the core findings of the definitive study on radiation exposure; while throughout the book, the author provides personal accounts that illustrate the human dimensions of the bombings. In a world where nuclear power is increasing and exposure to radiation is a daily occurrence, this book is essential reading for all scientists associated with public, private, or governmental institutions that set standards of acceptability for exposure.
This volume provides an extensive overview of radiation effects on integrated circuits, offering major guidelines for coping with radiation effects on components. It contains a set of chapters based on the tutorials presented at the International School on Effects of Radiation on Embedded Systems for Space Applications (SERESSA) that was held in Manaus, Brazil, November 20-25, 2005.
