Rabbit Biotechnology

Rabbit Biotechnology

Author: Louis-Marie Houdebine

Publisher: Springer Science & Business Media

Published: 2009-04-24

Total Pages: 135

ISBN-13: 9048122279

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Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiov- cular system and metabolism characteristics. Rabbit is thus more appropriate than mice to study some diseases such as atherosclerosis and lipid metabolism. Because of its larger size, surgery manipulation, bleeding, and turn-over studies are much easier performed in rabbits than in mice. Furthermore, transgenic rabbits can be produced using microinjection and other methods such as lentiviral v- tors. Cloning in rabbits has been proved possible, even though still laborious and time-consuming. Hopefully, functional rabbit ES cell lines will be available in the coming years. Gene deletion or knock-out in rabbits will then become possible.


The Genetics and Genomics of the Rabbit

The Genetics and Genomics of the Rabbit

Author: Luca Fontanesi

Publisher: CABI

Published: 2021-06-15

Total Pages: 361

ISBN-13: 1780643349

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Rabbits have many uses - as well as being cherished pets, they are bred for their meat and fur, and as laboratory animals. Understanding their genetics and genomics is key to their production and, equally, to their care, welfare and health. Beginning with an introduction to the rabbit, including key information on their evolution, domestication and breed types, this book then concentrates on the genetics and genomics of this valuable animal. Concluding with practical applications such as creating transgenic and genome edited rabbits, biotechnical applications and the rabbit as a biomedical model, this book brings this important topic fully up-to-date. It provides an indispensable resource for animal and veterinary researchers and students, as well as rabbit breeders and laboratory scientists.


Animal Biotechnology

Animal Biotechnology

Author: National Research Council

Publisher: National Academies Press

Published: 2002-11-29

Total Pages: 200

ISBN-13: 030916933X

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Genetic-based animal biotechnology has produced new food and pharmaceutical products and promises many more advances to benefit humankind. These exciting prospects are accompanied by considerable unease, however, about matters such as safety and ethics. This book identifies science-based and policy-related concerns about animal biotechnologyâ€"key issues that must be resolved before the new breakthroughs can reach their potential. The book includes a short history of the field and provides understandable definitions of terms like cloning. Looking at technologies on the near horizon, the authors discuss what we know and what we fear about their effectsâ€"the inadvertent release of dangerous microorganisms, the safety of products derived from biotechnology, the impact of genetically engineered animals on their environment. In addition to these concerns, the book explores animal welfare concerns, and our societal and institutional capacity to manage and regulate the technology and its products. This accessible volume will be important to everyone interested in the implications of the use of animal biotechnology.


Animals as Biotechnology

Animals as Biotechnology

Author: Richard Twine

Publisher: Earthscan

Published: 2010

Total Pages: 233

ISBN-13: 1849776350

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In Animals as Biotechnology sociologist Richard Twine places the question of human/animal relations at the heart of sustainability and climate change debates. The book is shaped by the emergence of two contradictory trends within our approach to nonhuman animals: the biotechnological turn in animal sciences, which aims to increase the efficiency and profitability of meat and dairy production; and the emerging field of critical animal studies - mostly in the humanities and social sciences - which works to question the nature of our relations with other animals. The first part of the book focuses on ethics, examining critically the dominant paradigms of bioethics and power relations between human and non-human. The second part considers animal biotechnology and political economy, examining commercialisation and regulation. The final part of the book centres on discussions of sustainability, limits and an examination of the prospects for animal ethics if biotechnology becomes part of the dominant agricultural paradigm. Twine concludes by considering whether growing calls to reduce our consumption of meat/dairy products in the face of climate change threats are in fact complicit with an anthropocentric understanding of sustainability and that what is needed is a more fundamental ethical and political questioning of relations and distinctions between humans, animals and nature.


The Biology of the Laboratory Rabbit

The Biology of the Laboratory Rabbit

Author: Patrick J. Manning

Publisher: Academic Press

Published: 2014-04-25

Total Pages: 500

ISBN-13: 148328882X

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After nearly 20 years, the publication of this Second Edition of The Biology of the Laboratory Rabbit attests to its popularity within the scientific community as well as to the need to update an expanding database on the rabbit as a major species in laboratory investigation. The principal aim of this text is to provide a comprehensive and authoritative source of scientifically based information on a major laboratory animal species. The text continues to emphasize the normal biology as well as diseases of the European (domestic) rabbit, Orytolagus cuniculus, especially the New Zealand White breed, with occasional reference to other rabbit species (Sylvilagus sp.) and hares (Lepus sp.). New topics have been added to this second edition in response to changing trends in biomedical research and product testing as well as to suggestions from readers.New chapters included on: - Anesthesia and analgesia - Models in infectious disease research - Models in ophthalmology and vision research - Polyclonal antibody production - Toxicity and safety testing - Drug doses and clinical reference data


Telepresence & Bio Art

Telepresence & Bio Art

Author: Eduardo Kac

Publisher: University of Michigan Press

Published: 2005

Total Pages: 342

ISBN-13: 9780472068104

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"Eduardo Kac's work represents a turning point. What it questions is our current attitudes to creativity, taking that word in its most fundamental sense." -Edward Lucie-Smith, author of Visual Arts in the 20th Century "His works introduce a vital new meaning into what had been known as the creative process while at the same time investing the notion of the artist-inventor with an original social and ethical responsibility." -Frank Popper, author of Origins and Development of Kinetic Art "Kac's radical approach to the creation and presentation of the body as a wet host for artificial memory and 'site-specific' work raises a variety of important questions that range from the status of memory in digital culture to the ethical dilemmas we are facing in the age of bioengineering and tracking technology." -Christiane Paul, Whitney Museum of Art For nearly two decades Eduardo Kac has been at the cutting edge of media art, first inventing early online artworks for the web and continuously developing new art forms that involve telecommunications and robotics as a new platform for art. Interest in telepresence, also known as telerobotics, exploded in the 1990s, and remains an important development in media art. Since that time, Kac has increasingly moved into the fields of biology and biotechnology. Telepresence and Bio Art is the first book to document the evolution of bio art and the aesthetic development of Kac, the creator of the "artist's gene" as well as the controversial glow-in-the-dark, genetically engineered rabbit Alba. Kac covers a broad range of topics within media art, including telecommunications media, interactive systems and the Internet, telematics and robotics, and the contact between electronic art and biotechnology. Addressing emerging and complex topics, this book will be essential reading for anyone interested in contemporary art.


DNA and Biotechnology

DNA and Biotechnology

Author: Molly Fitzgerald-Hayes

Publisher: Academic Press

Published: 2009-09-08

Total Pages: 401

ISBN-13: 008091635X

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Appropriate for a wide range of disciplines, from biology to non-biology, law and nursing majors, DNA and Biotechnology uses a straightforward and comprehensive writing style that gives the educated layperson a survey of DNA by presenting a brief history of genetics, a clear outline of techniques that are in use, and highlights of breakthroughs in hot topic scientific discoveries. Engaging and straightforward scientific writing style Comprehensive forensics chapter Parallel Pedagogic material designed to help both readers and teachers Highlights in the latest scientific discoveries Outstanding full-color illustration that walk reader through complex concepts


Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research

Author: National Research Council

Publisher: National Academies Press

Published: 1988-02-01

Total Pages: 113

ISBN-13: 0309038391

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Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.