Quantitative MRI of the Spinal Cord
Quantitative MRI of the Spinal Cord

Author: Julien Cohen-Adad

Publisher: Academic Press

Published: 2014-01-16

Total Pages: 331

ISBN-13: 0123972825

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Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. Chapters authored by international experts in the field of MRI of the spinal cord Contains “cooking recipes —examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice Ideal for clinical settings

Quantitative Magnetic Resonance Imaging
Quantitative Magnetic Resonance Imaging

Author: Nicole Seiberlich

Publisher: Academic Press

Published: 2020-11-18

Total Pages: 1094

ISBN-13: 0128170581

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Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Quantitative MRI of the Brain
Quantitative MRI of the Brain

Author: Paul Tofts

Publisher: John Wiley & Sons

Published: 2003

Total Pages: 678

ISBN-13: 9780470847213

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A 'how to' manual of quantitative MR, essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological diseases, its progression and its response to treatment. It is also designed for research-minded radiologists, neurologists and MRI physicists who are considering undertaking quantitative work, as well as those already in the field.

Myelin Water Measurement by Magnetic Resonance Imaging in the Healthy Human Spinal Cord
Myelin Water Measurement by Magnetic Resonance Imaging in the Healthy Human Spinal Cord

Author:

Publisher:

Published: 2008

Total Pages:

ISBN-13:

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Multi-echo T2 relaxation measurements of the human spinal cord (SC) reveal a short T2 pool of water believed to arise from water trapped between myelin bilayers, where the proportion of this water to the total water signal is called the myelin water fraction (MWF). In the present study, MWF were measured in the healthy human cervical spine at the C4-C6 vertebral levels in vivo using a 3D modified 32 echo CPMG sequence to acquire axial slices perpendicular to the cord. Volunteers were recruited in two age ranges, under 30 years old and over 50 years old, and a subset of both groups were scanned twice to test reproducibility. Mean MWF in the dorsal and lateral column WM of the group under 30 years of age was 0.29 (0.01) (mean(SE)), which agrees with previously reported MWF values in the cervical spine. The mean absolute difference between two scans was 0.06 or 26%. A negative correlation between WM MWF and age was hinted at in these findings, however more subjects are required to improve statistical power. This study paves the way for the use of 3D myelin water imaging in the cervical spine at 3.0T for the assessment of SC WM pathology.

Diseases of the Brain, Head and Neck, Spine 2020–2023
Diseases of the Brain, Head and Neck, Spine 2020–2023

Author: Juerg Hodler

Publisher: Springer Nature

Published: 2020-02-14

Total Pages: 252

ISBN-13: 303038490X

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This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Microstructural Parcellation of the Human Cerebral Cortex
Microstructural Parcellation of the Human Cerebral Cortex

Author: Stefan Geyer

Publisher: Springer Science & Business Media

Published: 2013-07-04

Total Pages: 260

ISBN-13: 3642378242

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Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.

McAlpine's Multiple Sclerosis
McAlpine's Multiple Sclerosis

Author: Alastair Compston

Publisher:

Published: 1998

Total Pages: 620

ISBN-13:

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This is the latest edition of the classic book on the subject of multiple sclerosis. An international group of authors has been involved in updating this edition which features more information on imaging and investigations, and a new chapter on neurobiology and glial development.