Quantitative Models for Microscopic to Macroscopic Biological Macromolecules and Tissues
Quantitative Models for Microscopic to Macroscopic Biological Macromolecules and Tissues

Author: Luis Olivares-Quiroz

Publisher: Springer

Published: 2018-02-26

Total Pages: 234

ISBN-13: 3319739751

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This book presents cutting-edge research on the use of physical and mathematical formalisms to model and quantitatively analyze biological phenomena ranging from microscopic to macroscopic systems. The systems discussed in this compilation cover protein folding pathways, gene regulation in prostate cancer, quorum sensing in bacteria to mathematical and physical descriptions to analyze anomalous diffusion in patchy environments and the physical mechanisms that drive active motion in large sets of particles, both fundamental descriptions that can be applied to different phenomena in biology. All chapters are written by well-known experts on their respective research fields with a vast amount of scientific discussion and references in order the interested reader can pursue a further reading. Given these features, we consider Quantitative Models for Microscopic to Macroscopic Biological Macromolecules and Tissues as an excellent and up-to-date resource and reference for advanced undergraduate students, graduate students and junior researchers interested in the latest developments at the intersection of physics, mathematics, molecular biology, and computational sciences. Such research field, without hesitation, is one of the most interesting, challenging and active of this century and the next.

Trends in Quorum Sensing and Quorum Quenching
Trends in Quorum Sensing and Quorum Quenching

Author: V. Ravishankar Rai

Publisher: CRC Press

Published: 2020-05-04

Total Pages: 628

ISBN-13: 1000051498

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The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments. Key features: Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on molecular mechanisms in bacterial signaling

Biosignal Processing and Classification Using Computational Learning and Intelligence
Biosignal Processing and Classification Using Computational Learning and Intelligence

Author: Alejandro A. Torres-García

Publisher: Academic Press

Published: 2021-09-18

Total Pages: 538

ISBN-13: 0128204281

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Biosignal Processing and Classification Using Computational Learning and Intelligence: Principles, Algorithms and Applications posits an approach for biosignal processing and classification using computational learning and intelligence, highlighting that the term biosignal refers to all kinds of signals that can be continuously measured and monitored in living beings. The book is composed of five relevant parts. Part One is an introduction to biosignals and Part Two describes the relevant techniques for biosignal processing, feature extraction and feature selection/dimensionality reduction. Part Three presents the fundamentals of computational learning (machine learning). Then, the main techniques of computational intelligence are described in Part Four. The authors focus primarily on the explanation of the most used methods in the last part of this book, which is the most extensive portion of the book. This part consists of a recapitulation of the newest applications and reviews in which these techniques have been successfully applied to the biosignals' domain, including EEG-based Brain-Computer Interfaces (BCI) focused on P300 and Imagined Speech, emotion recognition from voice and video, leukemia recognition, infant cry recognition, EEGbased ADHD identification among others. - Provides coverage of the fundamentals of signal processing, including sensing the heart, sending the brain, sensing human acoustic, and sensing other organs - Includes coverage biosignal pre-processing techniques such as filtering, artifiact removal, and feature extraction techniques such as Fourier transform, wavelet transform, and MFCC - Covers the latest techniques in machine learning and computational intelligence, including Supervised Learning, common classifiers, feature selection, dimensionality reduction, fuzzy logic, neural networks, Deep Learning, bio-inspired algorithms, and Hybrid Systems - Written by engineers to help engineers, computer scientists, researchers, and clinicians understand the technology and applications of computational learning to biosignal processing

2019-20 MATRIX Annals
2019-20 MATRIX Annals

Author: Jan de Gier

Publisher: Springer Nature

Published: 2021-02-10

Total Pages: 798

ISBN-13: 3030624978

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MATRIX is Australia’s international and residential mathematical research institute. It facilitates new collaborations and mathematical advances through intensive residential research programs, each 1-4 weeks in duration. This book is a scientific record of the ten programs held at MATRIX in 2019 and the two programs held in January 2020: · Topology of Manifolds: Interactions Between High and Low Dimensions · Australian-German Workshop on Differential Geometry in the Large · Aperiodic Order meets Number Theory · Ergodic Theory, Diophantine Approximation and Related Topics · Influencing Public Health Policy with Data-informed Mathematical Models of Infectious Diseases · International Workshop on Spatial Statistics · Mathematics of Physiological Rhythms · Conservation Laws, Interfaces and Mixing · Structural Graph Theory Downunder · Tropical Geometry and Mirror Symmetry · Early Career Researchers Workshop on Geometric Analysis and PDEs · Harmonic Analysis and Dispersive PDEs: Problems and Progress The articles are grouped into peer-reviewed contributions and other contributions. The peer-reviewed articles present original results or reviews on a topic related to the MATRIX program; the remaining contributions are predominantly lecture notes or short articles based on talks or activities at MATRIX.

Unifying Themes in Complex Systems IX
Unifying Themes in Complex Systems IX

Author: Alfredo J. Morales

Publisher: Springer

Published: 2018-07-23

Total Pages: 529

ISBN-13: 3319966618

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Unifying Themes in Complex Systems is a well-established series of carefully edited conference proceedings that serve to document and archive the progress made regarding cross-fertilization in this field. The International Conference on Complex Systems (ICCS) creates a unique atmosphere for scientists from all fields, engineers, physicians, executives, and a host of other professionals, allowing them to explore common themes and applications of complex systems science. With this new volume, Unifying Themes in Complex Systems continues to establish common ground between the wide-ranging domains of complex systems science.

Aging Research - Methodological Issues
Aging Research - Methodological Issues

Author: Carmen García-Peña

Publisher: Springer

Published: 2018-09-25

Total Pages: 249

ISBN-13: 3319953877

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This is the second edition of a well received book that reviews classical epidemiological and clinical research designs, with a specific focus on aging. Chapters cover basic topics like the scientific method, ethics, and the consequences of certain exclusion criteria. The work also includes a look at clinical concepts like multimorbidity, frailty and functionality. New material includes chapters such as geroscience, health systems research, big data and data mining, financing and future of aging research. The authors reveal the issues and challenges for researchers of age and aging, and also consider, from basic to clinical, and from clinical to public policies of social and health care. The focus on aging is what gives this book its valuable perspective on research methodology. All authors have considerable experience in aging, geriatrics or gerontology, and each chapter includes both a theoretical framework and practical examples of studies in aging. Readers will discover study designs that are reviewed for basic structure, main flaws and advantages, and are analyzed for specific conditions and variables regarding aging. This text is suited to both health care professionals caring for older adults, and researchers who are new to research in aging. It is relevant across the disciplines, including medicine, psychology, social sciences and dentistry, and it supports learning with graphs and figures.

Cancer: a complex disease
Cancer: a complex disease

Author: Octavio Miramontes

Publisher: CopIt ArXives

Published: 2018-12-04

Total Pages: 117

ISBN-13: 193812815X

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The study of complex systems and their related phenomena has become a major research venue in the recent years and it is commonly regarded as an important part of the scientific revolution developing through the 21st century. The science of complexity is concerned with the laws of operation and evolution of systems formed by many locally interacting elements that produce collective order at spatiotemporal scales larger than that of the single constitutive elements. This new thinking, that explores formally the emergence of spontaneous higher order and feedback hierarchies, has been particularly successful in the biological sciences. One particular life-threatening disease in humans, overwhelmingly common in the modern world is cancer. It is regarded as a collection of phenomena involving anomalous cell growth caused by an underlying genetic instability with the potential to spread to other parts of the human body. In the present book, a group of well recognised specialists discuss new ideas about the disease. These authors coming from solid backgrounds in physics, mathematics, medicine, molecular and cell biology, genetics and anthropology have dedicated their time to write an authoritative free-available text published under the open access philosophy that hopefully would be in the front-line struggle against cancer, a complex disease.

From Brain Dynamics to the Mind
From Brain Dynamics to the Mind

Author: Georg Northoff

Publisher: Elsevier

Published: 2024-04-01

Total Pages: 692

ISBN-13: 0128227397

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From Brain Dynamics to the Mind: Spatiotemporal Neuroscience explores how the self and consciousness is related to neural events. Sections in the book cover existing models used to describe the mind/brain problem, recent research on brain mechanisms and processes and what they tell us about the self, consciousness and psychiatric disorders. The book presents a spatiotemporal approach to understanding the brain and the implications for artificial intelligence, novel therapies for psychiatric disorders, and for ethical, societal and philosophical issues. Pulling concepts from neuroscience, psychology and philosophy, the book presents a modern and complete look at what we know, what we can surmise, and what we may never know about the distinction between brain and mind. - Reviews models of understanding the mind/brain problem - Identifies neural processes involved in consciousness, sense of self and brain function - Includes concepts and research from neuroscience, psychology, cognitive science and philosophy - Discusses implications for AI, novel therapies for psychiatric disorders and issues of ethics - Suggests experimental designs and data analyses for future research on the mind/brain issue

Understanding Light Microscopy
Understanding Light Microscopy

Author: Jeremy Sanderson

Publisher: John Wiley & Sons

Published: 2019-03-04

Total Pages: 851

ISBN-13: 1118696743

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Introduces readers to the enlightening world of the modern light microscope There have been rapid advances in science and technology over the last decade, and the light microscope, together with the information that it gives about the image, has changed too. Yet the fundamental principles of setting up and using a microscope rests upon unchanging physical principles that have been understood for years. This informative, practical, full-colour guide fills the gap between specialised edited texts on detailed research topics, and introductory books, which concentrate on an optical approach to the light microscope. It also provides comprehensive coverage of confocal microscopy, which has revolutionised light microscopy over the last few decades. Written to help the reader understand, set up, and use the often very expensive and complex modern research light microscope properly, Understanding Light Microscopy keeps mathematical formulae to a minimum—containing and explaining them within boxes in the text. Chapters provide in-depth coverage of basic microscope optics and design; ergonomics; illumination; diffraction and image formation; reflected-light, polarised-light, and fluorescence microscopy; deconvolution; TIRF microscopy; FRAP & FRET; super-resolution techniques; biological and materials specimen preparation; and more. Gives a didactic introduction to the light microscope Encourages readers to use advanced fluorescence and confocal microscopes within a research institute or core microscopy facility Features full-colour illustrations and workable practical protocols Understanding Light Microscopy is intended for any scientist who wishes to understand and use a modern light microscope. It is also ideal as supporting material for a formal taught course, or for individual students to learn the key aspects of light microscopy through their own study.