Quantitative Magnetic Resonance Imaging
Quantitative Magnetic Resonance Imaging

Author: Nicole Seiberlich

Publisher: Academic Press

Published: 2020-11-18

Total Pages: 1094

ISBN-13: 0128170581

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Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Quantitative Magnetic Resonance Imaging
Quantitative Magnetic Resonance Imaging

Author: Nicole Seiberlich

Publisher: Academic Press

Published: 2020-12-10

Total Pages: 1092

ISBN-13: 0128170573

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Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Diffusion MRI
Diffusion MRI

Author: Heidi Johansen-Berg

Publisher: Academic Press

Published: 2013-11-04

Total Pages: 627

ISBN-13: 0124055095

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Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. - Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging - Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments - New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain - Provides practical advice on running an experiment - Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience - Full color throughout

Quantitative MRI of the Spinal Cord
Quantitative MRI of the Spinal Cord

Author: Julien Cohen-Adad

Publisher: Academic Press

Published: 2014-01-16

Total Pages: 331

ISBN-13: 0123972825

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Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory's applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. - Chapters authored by international experts in the field of MRI of the spinal cord - Contains "cooking recipes—examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice - Ideal for clinical settings

Quantitative MRI in Cancer
Quantitative MRI in Cancer

Author: Thomas E. Yankeelov

Publisher: Taylor & Francis

Published: 2011-09-13

Total Pages: 331

ISBN-13: 1439820589

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Propelling quantitative MRI techniques from bench to bedside, Quantitative MRI in Cancer presents a range of quantitative MRI methods for assessing tumor biology. It includes biophysical and theoretical explanations of the most relevant MRI techniques as well as examples of these techniques in cancer applications.The introductory part of the book c

Quantitative MRI of the Brain
Quantitative MRI of the Brain

Author: Mara Cercignani

Publisher: CRC Press

Published: 2018-01-12

Total Pages: 342

ISBN-13: 1315363569

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Building on the success of the first edition of this book, the winner of the 2004 British Medical Association Radiology Medical Book Competition, Quantitative MRI of the Brain: Principles of Physical Measurement gives a unique view on how to use an MRI machine in a new way. Used as a scientific instrument it can make measurements of a myriad of physical and biological quantities in the human brain and body. For each small tissue voxel, non-invasive information monitors how tissue changes with disease and responds to treatment. The book opens with a detailed exposition of the principles of good practice in quantification, including fundamental concepts, quality assurance, MR data collection and analysis and improved study statistical power through minimised instrumental variation. There follow chapters on 14 specific groups of quantities: proton density, T1, T2, T2*, diffusion, advanced diffusion, magnetisation transfer, CEST, 1H and multi-nuclear spectroscopy, DCE-MRI, quantitative fMRI, arterial spin-labelling and image analysis, and finally a chapter on the future of quantification. The physical principles behind each quantity are stated, followed by its biological significance. Practical techniques for measurement are given, along with pitfalls and examples of clinical applications. This second edition of this indispensable 'how to' manual of quantitative MR shows the MRI physicist and research clinician how to implement these techniques on an MRI scanner to understand more about the biological processes in the patient and physiological changes in healthy controls. Although focussed on the brain, most techniques are applicable to characterising tissue in the whole body. This book is essential reading for anyone who wants to use the gamut of modern quantitative MRI methods to measure the effects of disease, its progression, and its response to treatment. Features: The first edition was awarded the book prize for Radiology by the British Medical Association in 2004 Written by an authority in the field: Professor Tofts has an international reputation for quantification in MRI Gives specific ‘how to’ information for implementation of MRI measurement sequence techniques

Quantitative MRI of the Brain
Quantitative MRI of the Brain

Author: Paul Tofts

Publisher: John Wiley & Sons

Published: 2005-08-19

Total Pages: 650

ISBN-13: 0470869496

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2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)

MRI from Picture to Proton
MRI from Picture to Proton

Author: Donald W. McRobbie

Publisher: Cambridge University Press

Published: 2017-04-13

Total Pages: 405

ISBN-13: 1316688259

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MR is a powerful modality. At its most advanced, it can be used not just to image anatomy and pathology, but to investigate organ function, to probe in vivo chemistry, and even to visualise the brain thinking. However, clinicians, technologists and scientists struggle with the study of the subject. The result is sometimes an obscurity of understanding, or a dilution of scientific truth, resulting in misconceptions. This is why MRI from Picture to Proton has achieved its reputation for practical clarity. MR is introduced as a tool, with coverage starting from the images, equipment and scanning protocols and traced back towards the underlying physics theory. With new content on quantitative MRI, MR safety, multi-band excitation, Dixon imaging, MR elastography and advanced pulse sequences, and with additional supportive materials available on the book's website, this new edition is completely revised and updated to reflect the best use of modern MR technology.

Electromagnetics in Magnetic Resonance Imaging
Electromagnetics in Magnetic Resonance Imaging

Author: Christopher M. Collins

Publisher: Morgan & Claypool Publishers

Published: 2016-03-01

Total Pages: 82

ISBN-13: 1681740834

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In the past few decades, Magnetic Resonance Imaging (MRI) has become an indispensable tool in modern medicine, with MRI systems now available at every major hospital in the developed world. But for all its utility and prevalence, it is much less commonly understood and less readily explained than other common medical imaging techniques. Unlike optical, ultrasonic, X-ray (including CT), and nuclear medicine-based imaging, MRI does not rely primarily on simple transmission and/or reflection of energy, and the highest achievable resolution in MRI is orders of magnitude smaller that the smallest wavelength involved. In this book, MRI will be explained with emphasis on the magnetic fields required, their generation, their concomitant electric fields, the various interactions of all these fields with the subject being imaged, and the implications of these interactions to image quality and patient safety. Classical electromagnetics will be used to describe aspects from the fundamental phenomenon of nuclear precession through signal detection and MRI safety. Simple explanations and Illustrations combined with pertinent equations are designed to help the reader rapidly gain a fundamental understanding and an appreciation of this technology as it is used today, as well as ongoing advances that will increase its value in the future. Numerous references are included to facilitate further study with an emphasis on areas most directly related to electromagnetics.

Magnetic Resonance Imaging
Magnetic Resonance Imaging

Author: Vadim Kuperman

Publisher: Elsevier

Published: 2000-03-15

Total Pages: 197

ISBN-13: 0080535704

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This book is intended as a text/reference for students, researchers, and professors interested in physical and biomedical applications of Magnetic Resonance Imaging (MRI). Both the theoretical and practical aspects of MRI are emphasized. The book begins with a comprehensive discussion of the Nuclear Magnetic Resonance (NMR) phenomenon based on quantum mechanics and the classical theory of electromagnetism. The first three chapters of this book provide the foundation needed to understand the basic characteristics of MR images, e.g.,image contrast, spatial resolution, signal-to-noise ratio, common image artifacts. Then MRI applications are considered in the following five chapters. Both the theoretical and practical aspects of MRI are emphasized. The book ends with a discussion of instrumentation and the principles of signal detection in MRI. - Clear progression from fundamental physical principles of NMR to MRI and its applications - Extensive discussion of image acquisition and reconstruction of MRI - Discussion of different mechanisms of MR image contrast - Mathematical derivation of the signal-to-noise dependence on basic MR imaging parameters as well as field strength - In-depth consideration of artifacts in MR images - Comprehensive discussion of several techniques used for rapid MR imaging including rapid gradient-echo imaging, echo-planar imaging, fast spin-echo imaging and spiral imaging - Qualitative discussion combined with mathematical description of MR techniques for imaging flow