Quantitative Anallysis Using Chromatographic Techniques
Author: E. Katz
Publisher: John Wiley & Sons
Published: 2009
Total Pages: 456
ISBN-13: 9788126519729
DOWNLOAD EBOOKRead and Download eBook Full
Author: E. Katz
Publisher: John Wiley & Sons
Published: 2009
Total Pages: 456
ISBN-13: 9788126519729
DOWNLOAD EBOOKAuthor: Steen Honoré Hansen
Publisher: John Wiley & Sons
Published: 2015-07-20
Total Pages: 332
ISBN-13: 1118716825
DOWNLOAD EBOOKBioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry is the first student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids with an educational presentation of the principles, concepts and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the different types of biological samples and fluids that are used; how to prepare the samples by extraction, and how to perform the appropriate analytical measurements by chromatographic and mass spectrometric methods. Bioanalysis of Pharmaceuticals: Sample Preparation, Separation Techniques and Mass Spectrometry: Is an introductory student textbook discussing the different principles and concepts clearly and comprehensively, with many relevant and educational examples Focuses on substances that are administered as human drugs, including low-molecular drug substances, peptides, and proteins Presents both the basic principles that are regularly taught in universities, along with the practical use of bioanalysis as carried out by researchers in the pharmaceutical industry and in hospital laboratories Is aimed at undergraduate students, scientists, technicians and researchers in industry working in the areas of pharmaceutical analyses, biopharmaceutical analyses, biological and life sciences The book includes multiple examples to illustrate the theory and application, with many practical aspects including calculations, thus helping the student to learn how to convert the data recorded by instruments into the real concentration of the drug substances within the biological sample.
Author: Bernd Spangenberg
Publisher: Springer Science & Business Media
Published: 2011-01-03
Total Pages: 399
ISBN-13: 364210729X
DOWNLOAD EBOOKThin-layer chromatography (TLC) is widely used particularly for pharmaceutical and food analysis. While there are a number of books on the qualitative identification of chemical substances by TLC, the unique focus here is on quantitative analysis. The authors describe all steps of the analytical procedure, beginning with the basics and equipment for quantitative TLC followed by sample pretreatment and sample application, development and staining, scanning, and finally statistical and chemometric data evaluation and validation. An important feature is the coverage of effect-directed biological detection methods. Chapters are organized in a modular fashion facilitating the easy location of information about individual procedural steps.
Author: Heinz Engelhardt
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 468
ISBN-13: 3642692257
DOWNLOAD EBOOKDuring its short 20 year history High Performance Liquid Chro matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis. HPLC has caused a revolution in biological and pharmaceutical chemistry. Approximately two thirds of the publications on HPLC are concerned with problems from this area of life science. Biotechnology, where it is necessary to isolate substances from complicated mixtures, is likely to give further impetus to the dissemination of modern liquid chromatog raphy in columns, particularly on the preparative scale. This book presents, by means of examples, the application of HPLC to various fields, as well as fundamental discussions of chromatographic methods. The quality of the analytical result is decisively dependent on the qualities of the equipment employed (by Colin, Guiochon, and Martin). Especially the demands are discussed that are placed on the components of the instrument including those for data acquisition and processing. The section on "quantitative analy sis" (by ABhauer, Ullner) covers besides the principles also the problems of ensuring the quality of the data in detail. The basic problems arising by enlarging the sample size to preparative di mensions and the requirements put on the aparatus are discussed in the section on "preparative applications" (by Wehrli).
Author: Walter Jennings
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 481
ISBN-13: 0323141056
DOWNLOAD EBOOKQualitative Analysis of Flavor and Fragrance Volatiles by Glass Capillary Gas Chromatography deals with the application of glass capillary gas chromatography to qualitative analysis of flavor and fragrance volatiles. Topics range from gas chromatographic system requirements and retention indices to selective detectors, ancillary reactions, and gas chromatography-mass spectrometry. This text is comprised of six chapters; the first of which provides an overview of the use of glass capillary gas chromatography in qualitative analysis of flavor and fragrance volatiles. The discussion then turns to gas chromatographic system requirements with respect to columns, inlets, detectors, and temperature control. The reader is also introduced to the Kovats retention index system, which utilizes a logarithmic scale to describe the retention behavior of a compound relative to that of the n-paraffin hydrocarbons. The use of selective detectors, such as thermal conductivity, flame ionization, nitrogen-phosphorus, electron capture, and photoionization detectors in qualitative analysis, is also considered. The final two chapters focus on ancillary reactions in glass capillary gas chromatography and general considerations in gas chromatography-mass spectrometry, including interfacing. This book is intended primarily for researchers involved in studies of the volatile constituents of fragrances, food, and natural products.
Author: Thomas Beesley
Publisher: CRC Press
Published: 2000-12-06
Total Pages: 322
ISBN-13: 0824745337
DOWNLOAD EBOOKHighlights critical factors involved in successful chromatographic analysis. Details analytical procedures; outlining sample preparation, collection, transportation, and storage. Provides step-by-step guidelines for producing analytical reports.
Author: Serban C. Moldoveanu
Publisher: Elsevier
Published: 2021-02-24
Total Pages: 698
ISBN-13: 0323898203
DOWNLOAD EBOOKModern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to make real-world samples amenable for chromatographic analysis and to improve results. This book's authors discuss each procedure's advantages, disadvantages and their applicability to different types of samples, along with their fit for different types of chromatographic analysis. The book contains numerous literature references and examples of sample preparation for different matrices and new sections on green approaches in sample preparation, progress in automation of sample preparation, non-conventional solvents for LLE (ionic liquids, deep eutectic mixtures, and others), and more. - Presents numerous techniques applied for sample preparation for chromatographic analysis - Provides an up-to-date source of information regarding the progress made in sample preparation for chromatography - Describes examples for specific types of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis
Author: Josef P Novák
Publisher: CRC Press
Published: 1987-12-18
Total Pages: 360
ISBN-13: 9780824778187
DOWNLOAD EBOOKAuthor: Łukasz Komsta
Publisher: CRC Press
Published: 2018-02-02
Total Pages: 506
ISBN-13: 1498772544
DOWNLOAD EBOOKChemometrics uses advanced mathematical and statistical algorithms to provide maximum chemical information by analyzing chemical data, and obtain knowledge of chemical systems. Chemometrics significantly extends the possibilities of chromatography and with the technological advances of the personal computer and continuous development of open-source software, many laboratories are interested in incorporating chemometrics into their chromatographic methods. This book is an up-to-date reference that presents the most important information about each area of chemometrics used in chromatography, demonstrating its effective use when applied to a chromatographic separation.
Author: Daniel C. Harris
Publisher: Macmillan Higher Education
Published: 2015-05-29
Total Pages: 998
ISBN-13: 131904803X
DOWNLOAD EBOOKThe gold standard in analytical chemistry, Dan Harris’ Quantitative Chemical Analysis provides a sound physical understanding of the principles of analytical chemistry and their applications in the disciplines