Purinergic Signaling 2020: the State-of-The-Art Commented by the Members of the Italian Purine Club
Author: Francesco Caciagli
Publisher: Frontiers Media SA
Published: 2021-10-29
Total Pages: 287
ISBN-13: 2889715701
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Introduction to Basics of Pharmacology and Toxicology
Author: Abialbon Paul
Publisher: Springer Nature
Published: 2021-03-13
Total Pages: 1156
ISBN-13: 9813360097
DOWNLOAD EBOOKThis book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Hypoxia and the Circulation
Author: Robert Roach
Publisher: Springer
Published: 2007-12-26
Total Pages: 0
ISBN-13: 9780387754338
DOWNLOAD EBOOKJust one of a series of volumes on differing aspects of hypoxia, this authoritative text focuses on cutting-edge research at the interface of hypoxia and biomedicine. Hypoxia – or lack of oxygen – is a constant threat to the human body and its vital organs, one that can take its toll in a number of situations. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. The International Hypoxia Symposia was founded to enable scientists, clinicians, physiologists, immunologists, mountaineers and other interested individuals to share their experiences of the situations associated with the lack of oxygen and the adaptations that allow us to survive.
Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology
Author: Luiz Belardinelli
Publisher: Springer Science & Business Media
Published: 1995-03-31
Total Pages: 584
ISBN-13: 9780792331902
DOWNLOAD EBOOKThis book contains 55 chapters that summarize referred to the special issue of Drug Development lectures given during the Fifth International Research (Volume 31, Number 4, April 1994). Symposium on Adenosine and Adenine Measured by the number and quality of presenta- Nucleotides held in Philadelphia, Pennsylvania, tions, and by the record number of participants, U. S. A., May 9-13, 1994. The symposium and the Fifth International Symposium on Adenosine its proceedings follow four previous symposia and Adenine Nucleotides was clearly an intel- and their published proceedings. Previous sym- lectually stimulating meeting. It is safe to posia were held in Banfff, Canada (1978), conclude that the purine research field is vibrant Charlottesville, Virginia (1982), Munich, and still growing. Adenosine has rapidly become Germany (1986), and Lake Yamanaka, Japan the drug of choice for the acute management (1990). of supraventricular tachyarrhythmias and was The program included a wide range of sub- recently approved for use in combination with jects from molecular and cellular biology to cardiac imaging for detection of ischemic heart clinical applications. Great emphasis was placed disease. Additional clinical applications of on cutting edge information derived from studies adenosine and adenosine-related drugs and ATP using molecular and cellular biology techniques seem closer than ever before. The editors would like to express their grati- applied to the field of adenosine and adenine nucleotide research. Likewise, the program tude to the distinguished contributors for their included a number of presentations on poten- excellent chapters and to all participants.
In Praise Of Imperfe
Author: Rita Levi-Montalcini
Publisher:
Published: 1988-05-08
Total Pages: 254
ISBN-13:
DOWNLOAD EBOOKThe autobiography of Levi-Montalcini, who won the Nobel Prize for Medicine in 1986. Born in Torino into a middle-class Jewish family, she experienced the rise of fascism and antisemitism in the 1930s-40s (discussed on pp. 73-105). After the promulgation of the racial laws in 1938, it was impossible for her to pursue research at the Neurological Clinic and she continued her work in private. She survived the war hiding in a small town in Italy and later emigrated to the United States.
Perspectives of Stem Cells
Author: Henning Ulrich
Publisher: Springer Science & Business Media
Published: 2010-01-14
Total Pages: 300
ISBN-13: 9048133750
DOWNLOAD EBOOKStem cells are fascinating cell types. They can replicate themselves forever while retaining the potential to generate progeny with speci?c functions. Because of these special properties, stem cells have been subjects of intensive investigation, from understanding basic mechanisms underlying tissue generation, to modeling human diseases, to application for cell replacement therapy. Stem cells come in different forms. For example, mouse embryonic stem cells can general all cell types in a body, either in a dish or when put back into mouse embryos. On the other hand, neural stem cells in the adult brain generate neurons and glia cells that contribute to the brain’s plasticity. Rapid progress has been made in the stem cell ?eld with discov- ies published in a record speed. A quick Pubmed search has returned 2789 hits for “embryonic stem cells” and 815 hits for “adult neural stem cells/neurogenesis” in the year 2008 alone. It remains a taunting task for all who are interested in stem cells to keep up with rapidly accumulating literatures. The “Perspectives of Stem Cells” by a truly international team of experts provides a timely and invaluable highlight of the stem cell ?eld gearing toward future therapeutic applications in the nervous system. Stem cells with neural potentials have attracted a lot of attention because of their promise for cell replacement therapy, ranging from degenerative neurological dis- ders to spinal cord injuries.
P-adic Aspects Of Modular Forms
Author: Baskar Balasubramanyam
Publisher: World Scientific
Published: 2016-06-14
Total Pages: 342
ISBN-13: 9814719242
DOWNLOAD EBOOKThe aim of this book is to give a systematic exposition of results in some important cases where p-adic families and p-adic L-functions are studied. We first look at p-adic families in the following cases: general linear groups, symplectic groups and definite unitary groups. We also look at applications of this theory to modularity lifting problems. We finally consider p-adic L-functions for GL(2), the p-adic adjoint L-functions and some cases of higher GL(n).
Cytometry, Part A
Author:
Publisher: Elsevier
Published: 2000-10-31
Total Pages: 683
ISBN-13: 0080522521
DOWNLOAD EBOOKEach chapter presents a detailed background of the described method, its theoretical foundations, and its applicability to different biomedical material. Updated chapters describe either the most popular methods or those processes that have evolved the most since the past edition. Additionally, a large portion of the volume is devoted to clinical cytometry. Particular attention is paid to applications of cytometry in oncology, the most rapidly growing area. - Contains 56 extensive chapters authored by world authorities on cytometry - Covers a wide range of topics, including principles of cytometry and general methods, cell preparation, tandardization and quality assurance, cell proliferation, apoptosis, cell-cell/cell-environmental interactions, cytogenetics and molecular genetics, cell function and differentiation, experimental and clinical oncology, microorganisms, and infectious diseases - Describes in-depth the essential methods and scientific principles of flow and laser scanning cytometry and illustrates how they can be applied to the fields of biology and medicine - Complements the first and second editions on flow cytometry in the Methods in Cell Biology series and includes new sections on technology principles
Molecular Infection Biology
Author: Jörg Hinrich Hacker
Publisher: Wiley-Spektrum
Published: 2002-10-03
Total Pages: 370
ISBN-13:
DOWNLOAD EBOOKThis comprehensive volume focuses on molecular methods and principles of prokaryotic and eukaryotic pathogens. The authors present the molecular and cellular aspects by focusing on the interactions between pathogenic microorganisms and their hosts. The publication begins with an overview of the most important and dangerous causative agents of infectious diseases. Next are discussions of how microbial "weapons," pathogenicity factors, protein secretion machines, and surface variation systems work, presenting the molecular and genetic methods that are used by scientists for their discovery and analysis. Furthermore, infectious diseases are discussed in light of the newly formed research areas of evolutionary and cellular microbiology and genomics. Future aspects on diagnostic techniques, therapy, and vaccine development are also presented.
Medicinal Chemistry and Pharmacology
Author: Avianna Stokes
Publisher:
Published: 2019-06-25
Total Pages: 222
ISBN-13: 9781632415356
DOWNLOAD EBOOKMedicinal chemistry and pharmacology are closely associated fields. They are concerned with the design and synthesis of drugs for the pharmaceutical industry. These drugs are generally organic compounds and can be divided into classes of biologics and small organic compounds. Medicinal chemistry is focused on the production of small organic molecules such as atorvastatin, fluticasone, clopidogrel, etc. The principles of synthetic organic chemistry, computational chemistry, enzymology, structural biology and chemical biology are integrated in medicinal chemistry. The study of drugs and their effects on the living body are explored in pharmacology. It involves the research, discovery and characterization of the chemicals that exhibit a biological effect. All therapies that are designed to target diseases, defects and pathogens and also advance preventive care, diagnostics and personalized medicine are a result of tremendous research in pharmacology. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the fields of medicinal chemistry and pharmacology. The various advancements in these fields are glanced at and their applications as well as ramifications are looked at in detail. This book is a vital tool for all researching and studying pharmaceutical science and medicinal chemistry.
