Pulmonary Biology in Health and Disease

Pulmonary Biology in Health and Disease

Author: Edward E. Bittar

Publisher: Springer Science & Business Media

Published: 2002-09-10

Total Pages: 439

ISBN-13: 0387952152

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This new book provides an accessible review of the field of lung biology and disease aimed at the graduate or medical student and biomedical researcher. The book starts by considering the anatomy and ultrastructure of the lung and the tracheal and bronchial system, the control of respiration as well as the fundamentals of pulmonary physiology, gas exchange and circulation. This is followed by discussion of the regulation of acid-base balance, high altitude physiology and pathophysiology as well as exercise and the pulmonary system. Chapters follow on the immunology of the lung, lung injury, asthma and emphysema, granulomatous lung disease, inhalation of toxic substances as well as diseases of the small airways. The final chapter considers current research into lung transplantation.


Drug Delivery to the Lung

Drug Delivery to the Lung

Author: Hans Bisgaard

Publisher: CRC Press

Published: 2001-10-02

Total Pages: 536

ISBN-13: 0824741978

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This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract!Featuring over 1300 references, drawings, tables, and photographs.


How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease

Author: United States. Public Health Service. Office of the Surgeon General

Publisher:

Published: 2010

Total Pages: 728

ISBN-13:

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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.


Lung Surfactants

Lung Surfactants

Author: Robert H. Notter

Publisher: CRC Press

Published: 2000-07-18

Total Pages: 476

ISBN-13: 9780824704018

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Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease. Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effectively!


Lung Development and Regeneration

Lung Development and Regeneration

Author: Donald J. Massaro

Publisher: CRC Press

Published: 2004-09-09

Total Pages: 608

ISBN-13: 9780824754396

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This reference compiles the most current technical and biological data available to survey the state-of-science in the care and management of patients with bronchopulmonary dysplasia, COPD, and other forms of lung disease-tracking the initiation and progression of processes that cause airway obstruction, the biologic and physiological abnormalities that characterize COPD, and the potential reversibility of the inflammatory response in COPD for improved patient diagnosis and treatment.


Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease

Author: Venkataramana K Sidhaye

Publisher: Academic Press

Published: 2017-03-09

Total Pages: 277

ISBN-13: 0128038810

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Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. - Provides a single source of information on lung epithelial junctions and transporters - Discusses of the role of the epithelium in lung homeostasis and disease - Includes capsule summaries of main conclusions as well as highlights of future directions in the field - Covers the mechanistic basis for lung disease for a range of audiences


Respiratory-Circulatory Interactions in Health and Disease

Respiratory-Circulatory Interactions in Health and Disease

Author: Steven M. Scharf

Publisher: CRC Press

Published: 2001-04-27

Total Pages: 997

ISBN-13: 0824741749

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This book describes the basic, pathophysiologic, and clinical importance of the reciprocal relationships and interactions between the respiratory and cardiovascular systems, examining mechanical responses caused by lung volume and thoracic pressure. Emphasizes humoral and neurophysical interactions occurring in diseases that lead to cardiorespi


Primary Pulmonary Hypertension

Primary Pulmonary Hypertension

Author: Lewis J. Rubin

Publisher: CRC Press

Published: 1996-11-06

Total Pages: 384

ISBN-13: 9780824795054

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Detailing state-of-the-art developments in the various aspects of primary pulmonary hypertension (PPH), this practical reference explores the history, most current scientific concepts, and treatments of this disease. Includes new advances not yet formally published! Written by nearly 30 of the top international experts in the field, Primary Pulmonary Hypertension addresses the general histological features of the normal and hypertensive pulmonary vasculature and the pathology of PPH discusses etiological possibilities of pathogenesis, common morphological features, and findings in experimental models examines risks factors for PPH and looks separately at familial PPH and PPH in children presents an approach to the differential diagnosis of pulmonary hypertension, emphasizing the recognition of PPH elucidates the invasive and noninvasive modalities available for obtaining qualitative and quantitative hemodynamic data for the diagnosis of PPH covers a variety of therapeutic options and much more!


Chronic Lung Disease in Early Infancy

Chronic Lung Disease in Early Infancy

Author: Richard D. Bland

Publisher: CRC Press

Published: 1999-09-21

Total Pages: 0

ISBN-13: 9780824798710

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This definitive volume presents the clinical and pathological features of bronchopulmonary dysplasia, a disease that accounts for the majority of long-term hospitalizations, slow growth, and recurrent early childhood respiratory ailments that are common in low-birth-weight newborns. Highlights relevant animal models for studying the process of chronic lung disease through its evolution and during recovery! Written by nearly 75 leading international authorities on lung disease during early childhood development who describe the clinical, radiographic, and pathological changes that have occurred in the 30 years since bronchopulmonary dysplasia was first discovered, Chronic Lung Disease in Early Infancy focuses on the development of technology, notably changes in the application of assisted ventilation traces the evolution and impact of new therapies, including prenatal glucocorticoids and postnatal surfactants suggests effective therapeutic and preventive strategies explains how the lungs develop structurally and functionally explores how lung development is altered by injury and the repair process critically examines research in the field of pediatric lung pathology reviews what is known and emphasizes what needs to be learned about bronchopulmonary dysplasia provides direction for future research into chronic lung disease and more!


Pulmonary Biology in Health and Disease

Pulmonary Biology in Health and Disease

Author: Edward E. Bittar

Publisher: Springer Science & Business Media

Published: 2007-05-28

Total Pages: 439

ISBN-13: 0387224351

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Pulmonary Biology in Health and Disease was conceived as a companion to a handful of expensive, multivolume textbooks. This is part of the promising trend to publish shorter textbooks on the subjects of lung biology and remodeling. Whoever is familiar with human biology and the far-reaching consequences of the genome and postgenome revolutions is apt to concede that the centerpiece in remodeling lies in the ?eld of m- ecular cardiobiology. The ?eld of molecular cardiobiology includes the syndrome of chronic heart failure as well as ischemic cardioprotection. By analogy, the centerpiece in pulmonobiology is chronic asthma. Key topics in the present volume include s- naling mechanisms regulating the endothelium and smooth muscle cells,in?ammatory cells, mediators, airway surface liquid, and pharmacological therapy that focuses on how in?amed airways are altered. Written primarily for predoctoral and postdoctoral graduates in the basic medical sciences, the medical student and postdoctoral physician, graduates in the allied s- ences, nurses, pulmonologists, and physicians in critical care medicine, this book p- vides many of the fundamentals of contemporary pulmonology. It is divided into several parts devoted to the control of respiration, arterial chemoreceptors,muscles of ventilation, pulmonary physiology, and gas exchange in health, exercise, and disease. Special emphasis is placed on emphysema and its pathobiology, acute lung injury, asthma and inhaled toxicants. Because the ?eld is always evolving, each chapter includes recommended readings that lead the reader to sources of additional information, such as the review on remodeling of the blood gas barrier by West and Mathieu-Costello.