Protein Kinase C and Its Brain Substrates
Author: Willem Hendrik Gispen
Publisher:
Published: 1991
Total Pages: 292
ISBN-13: 9780444814364
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Author: Willem Hendrik Gispen
Publisher:
Published: 1991
Total Pages: 292
ISBN-13: 9780444814364
DOWNLOAD EBOOKAuthor: Willem Hendrik Gispen
Publisher:
Published: 1991
Total Pages: 292
ISBN-13: 9780444801043
DOWNLOAD EBOOKAuthor: W H. Gispen
Publisher:
Published: 1991
Total Pages:
ISBN-13: 9780444801043
DOWNLOAD EBOOKAuthor: International Meeting on Brain Phosphoproteins
Publisher:
Published: 1991
Total Pages: 292
ISBN-13: 9780444801043
DOWNLOAD EBOOKAuthor: Alexandra C. Newton
Publisher: Springer Science & Business Media
Published: 2008-02-03
Total Pages: 565
ISBN-13: 1592593976
DOWNLOAD EBOOKSince the discovery that protein kinase C (PKC) transduces the ab- dance of signals that result in phospholipid hydrolysis, this enzyme has been at the forefront of research in signal transduction. Protein Kinase C Protocols covers fundamental methods for studying the structure, function, regulation, subcellular localization, and macromolecular interactions of PKC. Protein Kinase C Protocols is divided into 11 sections representing the major aspects of PKC regulation and function. Part I contains an introduction and a historical perspective on the discovery of PKC by Drs. Yasutomi Nishizuka and Ushio Kikkawa. Part II describes methods to purify PKC. Part III describes the standard methods for measuring PKC activity: its enzymatic activity and its stimulus-dependent translocation from the cytosol to the membrane. Part IV describes methods for measuring the membrane interaction of PKC in vivo and in vitro. Part V provides methodologies and techniques for measuring the ph- phorylation state of PKC, including a protocol for measuring the activity of PKC’s upstream kinase, PDK-1. Novel methods for identifying substrates are described in Part VI. Part VII presents protocols for expressing and analyzing the membrane targeting domains of PKC. Part VIII provides a comprehensive c- pilation of methods used to identify binding partners for PKC. Part IX describes pharmacological probes used to study PKC. The book ends with a presentation of genetic approaches to study PKC (Part X) and a discussion of approaches used to study PKC in disease (Part XI).
Author: David Simon Lester
Publisher: Prentice Hall
Published: 1992
Total Pages: 392
ISBN-13:
DOWNLOAD EBOOKAttempts to provide a detailed study of a protein which plays an important role in the regulation of numerous cellular processes. The volume contains reviews of current research in the field and provides a background to the techniques and concepts necessary for future developments.
Author: Lodewijk V. Dekker
Publisher: Springer Science & Business Media
Published: 2004-06-17
Total Pages: 212
ISBN-13: 9780306478635
DOWNLOAD EBOOKProtein Kinase C is a pivotal component of the mechanism that allows a cell to respond to its changing environment. In this book, the most significant advances in recent basic research on Protein Kinase C are explained by active researchers in the field. The first seven chapters provide a comprehensive account of the fundamental structural and biochemical properties of Protein Kinase C. The remaining chapters contain overviews of the function of Protein Kinase C, both in lower organisms and in mammalian cells, the latter with a focus on immune cells and nerve cells. This book is the only recent publication devoted entirely to Protein Kinase C and forms a major point of reference for those active in the field. In addition it will appeal to those with a general interest in biochemistry, cell biology, immunology and neurobiology.
Author: Robert Brelsford Nelson
Publisher:
Published: 1987
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor: Benny Björkblom
Publisher:
Published: 2008
Total Pages: 100
ISBN-13:
DOWNLOAD EBOOKAuthor: Phillip S. Leventhal
Publisher:
Published: 1993
Total Pages: 508
ISBN-13:
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