Apoptosis and Cancer
Author: Seamus J. Martin
Publisher: R G Landes Company
Published: 1997
Total Pages: 265
ISBN-13: 9781570594526
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Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
Author: Christopher D. Gregory
Publisher: Springer
Published: 2016-08-24
Total Pages: 260
ISBN-13: 3319394061
DOWNLOAD EBOOKThis book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
Innovative Medicine
Author: Kazuwa Nakao
Publisher: Springer
Published: 2015-10-13
Total Pages: 330
ISBN-13: 4431556516
DOWNLOAD EBOOKThis book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Necrotic Cell Death
Author: Han-Ming Shen
Publisher: Springer Science & Business Media
Published: 2014-03-29
Total Pages: 402
ISBN-13: 1461482208
DOWNLOAD EBOOKStarting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
Apoptosis, Senescence and Cancer
Author: David A. Gewirtz
Publisher: Springer Science & Business Media
Published: 2007-12-17
Total Pages: 596
ISBN-13: 1588295273
DOWNLOAD EBOOKProvides insight into established practices and research into apoptosis and senescence by examining techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics which still hold mysteries for researchers. This book concludes with established cancer therapies.
Programmed Cell Death in Cancer Progression and Therapy
Author: Roya Khosravi-Far
Publisher: Springer Science & Business Media
Published: 2007-12-29
Total Pages: 362
ISBN-13: 140206554X
DOWNLOAD EBOOKProgrammed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mechanisms involved in mediating and regulating PCD in cancer. It also provides a detailed indication of the utility of PCD in cancer therapy. The book features chapters on the current and future of RNA interference in therapeutics and Pathways involved in Stem Cell Survival and Death.
Cell Death
Author: Douglas R. Green
Publisher:
Published: 2018
Total Pages: 0
ISBN-13: 9781621822141
DOWNLOAD EBOOKA million cells in our bodies die every second--they commit suicide by activating a process called apoptosis or other forms of programmed cell death. These mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes, the immune system, and cancer. In this second edition of Douglas Green's essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining the machinery that connects them to signals that cause cell death. He also describes the roles of cell death in development, neuronal selection, and the development of self-tolerance in the immune system, as well as how the body uses cell death to defend against cancer. The new edition is fully updated to cover the many recent advances in our understanding of the death machinery and signals that control cell death. These include the mechanisms regulating necroptosis, mitophagy, and newly identified processes, such as ferroptosis. The book will thus be of great interest to researchers actively working in the field, as well as biologists and undergraduates encountering the topic for the first time.
When Cells Die II
Author: Richard A. Lockshin
Publisher: Wiley-Liss
Published: 2004
Total Pages: 578
ISBN-13:
DOWNLOAD EBOOKOffers the most thorough, cutting-edge coverage of the field of cell death since publication of the first edition. Leading international researchers present an up-to-date yet accessible survey ranging from the history of cell death science to its modern methodology. Extensively revised, this new edition features relavant discussions of: the impact of genomics and proteomics; gene therapy and pharmacogenetics; the role of mitochondria; caspase-independent and non-apoptotic cell death; and evolution of mechanisms.
Mechanisms of Cell Death
Author: Zahra Zakeri
Publisher:
Published: 1999
Total Pages: 236
ISBN-13:
DOWNLOAD EBOOKContains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics
Flight of the Turtle
Author: Samuel Ruder
Publisher:
Published: 2023-04-10
Total Pages: 0
ISBN-13:
DOWNLOAD EBOOKFlight of the Turtle is a story about the power of love and a turtle that learns to fly. Vivid color and simple words are used to paint this story told through the eyes of a fisherman who loves the beauty of the sea and loves returning home to the harbor where his faithful cats eagerly await.
