Molecular Pharming
Molecular Pharming

Author: Allison R. Kermode

Publisher: John Wiley & Sons

Published: 2018-05-08

Total Pages: 495

ISBN-13: 1118801288

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A single volume collection that surveys the exciting field of plant-made pharmaceuticals and industrial proteins This comprehensive book communicates the recent advances and exciting potential for the expanding area of plant biotechnology and is divided into six sections. The first three sections look at the current status of the field, and advances in plant platforms and strategies for improving yields, downstream processing, and controlling post-translational modifications of plant-made recombinant proteins. Section four reviews high-value industrial and pharmacological proteins that are successfully being produced in established and emerging plant platforms. The fifth section looks at regulatory challenges facing the expansion of the field. The final section turns its focus toward small molecule therapeutics, drug screening, plant specialized metabolites, and plants as model organisms to study human disease processes. Molecular Pharming: Applications, Challenges and Emerging Areas offers in-depth coverage of molecular biology of plant expression systems and manipulation of glycosylation processes in plants; plant platforms, subcellular targeting, recovery, and downstream processing; plant-derived protein pharmaceuticals and case studies; regulatory issues; and emerging areas. It is a valuable resource for researchers that are in the field of plant molecular pharming, as well as for those conducting basic research in gene expression, protein quality control, and other subjects relevant to molecular and cellular biology. Broad ranging coverage of a key area of plant biotechnology Describes efforts to produce pharmaceutical and industrial proteins in plants Provides reviews of recent advances and technology breakthroughs Assesses realities of regulatory and cost hurdles Forward looking with coverage of small molecule technologies and the use of plants as models of human disease processes Providing wide-ranging and unique coverage, Molecular Pharming: Applications, Challenges and Emerging Areas will be of great interest to the plant science, plant biotechnology, protein science, and pharmacological communities.

Extremophiles
Extremophiles

Author: Om V. Singh

Publisher: John Wiley & Sons

Published: 2012-10-16

Total Pages: 696

ISBN-13: 1118394119

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Explores the utility and potential of extremophiles in sustainability and biotechnology Many extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development. Extremophiles features outstanding articles by expert scientists who shed light on broad-ranging areas of progress in the development of smart therapeutics for multiple disease types and products for industrial use. It bridges technological gaps, focusing on critical aspects of extremolytes and the mechanisms regulating their biosynthesis that are relevant to human health and bioenergy, including value-added products of commercial significance as well as other potentially viable products. This groundbreaking guide: Introduces the variety of extremophiles and their extremolytes including extremozymes Provides an overview of the methodologies used to acquire extremophiles Reviews the literature on the diversity of extremophiles Offers tools and criteria for data interpretation of various extremolytes/extremozymes Discusses experimental design problems associated with extremophiles and their therapeutic implications Explores the challenges and possibilities of developing extremolytes for commercial purposes Explains the FDA's regulations on certain microbial bio-products that will be of interest to potential industrialists Extremophiles is an immensely useful resource for graduate students and researchers in biotechnology, clinical biotechnology, microbiology, and applied microbiology.

Cellular Agriculture
Cellular Agriculture

Author: Dilek Ercili-Cura

Publisher: American Chemical Society

Published: 2021-03-16

Total Pages: 186

ISBN-13: 0841299080

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Cellular agriculture, also called lab-grown food, promises to provide alternative food options to current agriculture practices. Cellular agriculture is food grown in laboratories and bioreactors rather than on fields, relying on cultivation of cells under controlled conditions, with minimal use of natural resources and lower greenhouse gas emission costs than in traditional practices. It gives us the prospect of consuming the same foods such as a dairy ice cream or a burger. And it can further broaden the variety of textures, flavors, nutrition, and health-promoting aspects that food can deliver. Cellular Agriculture: Lab-Grown Foods gives an overview of the broad range of approaches to cellular agriculture, the current state of scale and regulations, and the results it brings about in terms of environmental footprint and consumer attitudes. Cellular Agriculture: Lab-Grown Foods was organized by Solar Foods, a food-tech company that develops a cell-based food protein produced from CO2 and electricity. A fruitful collaboration with VTT Technical Research Center of Finland Ltd allowed conceptualizing and streamlining of the written and visual content in the book.

Biotechnology of Natural Products
Biotechnology of Natural Products

Author: Wilfried Schwab

Publisher: Springer

Published: 2017-11-16

Total Pages: 317

ISBN-13: 3319679031

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This text comprehensively covers the analysis, enzymology, physiology and genetics of valuable natural products used in the food industry that are attractive targets for biotechnological production. The focus is on the recent advances made to achieve this goal. This unique work is the first book to focus on biotechnological production of important natural products in food additives, fragrances and flavorings, and other bioactive compounds in food. The chapters offer a deep insight into modern research and the development of low molecular weight natural products. Biotechnology of Natural Products covers products in the Phenolic, Terpenoid, and Alkaloid categories, providing a full overview of the biotechnology of food additives and other low molecular weight natural products. Gene clustering and the evolution of pathways are covered, as well as future perspectives on the topic. Due to limited oil resources and increasing consumer demand for naturalness, bioprocesses are increasingly needed to meet these requirements. Novel sophisticated technologies have facilitated the elucidation of new chemical molecules, their biosynthetic pathways and biological functions. This book provides researchers with a full overview of the technologies and processes involved in the biotechnology of natural products.

Guidelines for Slope Performance Monitoring
Guidelines for Slope Performance Monitoring

Author: Robert Sharon

Publisher: CSIRO PUBLISHING

Published: 2020-07-01

Total Pages: 561

ISBN-13: 1486311016

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Although most mining companies utilise systems for slope monitoring, experience indicates that mining operations continue to be surprised by the occurrence of adverse geotechnical events. A comprehensive and robust performance monitoring system is an essential component of slope management in an open pit mining operation. The development of such a system requires considerable expertise to ensure the monitoring system is effective and reliable. Written by instrumentation experts and geotechnical practitioners, Guidelines for Slope Performance Monitoring is an initiative of the Large Open Pit (LOP) Project and the fifth book in the Guidelines for Open Pit Slope Design series. Its 10 chapters present the process of establishing and operating a slope monitoring system; the fundamentals of pit slope monitoring instrumentation and methods; monitoring system operation; data acquisition, management and analysis; and utilising and communicating monitoring results. The implications of increased automation of mining operations are also discussed, including the future requirements of performance monitoring. Guidelines for Slope Performance Monitoring summarises leading mine industry practice in monitoring system design, implementation, system management, data management and reporting, and provides guidance for engineers, geologists, technicians and others responsible for geotechnical risk management.

Plant Cyclotides
Plant Cyclotides

Author:

Publisher: Academic Press

Published: 2015-11-24

Total Pages: 404

ISBN-13: 0128007974

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Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 76th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. Publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences Contains commentary by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology This volume features reviews of the fast moving field of plant cyclotides

Olive and Olive Oil Bioactive Constituents
Olive and Olive Oil Bioactive Constituents

Author: Dimitrios Boskou

Publisher: Elsevier

Published: 2015-08-15

Total Pages: 422

ISBN-13: 1630670421

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The market is flooded with products posing as elixirs, supplements, functional foods, and olive oil alternatives containing phenols obtained from multiple olive sources. This technically-oriented book will be of value to nutritionists and researchers in the biosciences. It unravels the body of science pertaining to olive minor constituents in relation to new chemical knowledge, technological innovations, and novel methods of recovery, parallel to toxicology, pharmacology, efficacy, doses, claims, and regulation. Topics include: the biological importance of bioactive compounds present in olive products; developments and innovations to preserve the level of bioactives in table olives and olive oil; and importance of variety, maturity, processing of olives, storage, debittering of olives and table olives as a valuable source of bioactive compounds. Presents detailed information concerning the claimed benefits of olive oil and discusses the permitted health claim to EFSA on oils with natural phenolics Recovery of bioactive constituents from olive waste is comprehensively described Explores the relationship betwen phenolic levels and sensory evaluation Features chapters on the clinical and cellular mechanisms and health effects of olive, important for functional foods research