Principles and Models of Biological Transport

Principles and Models of Biological Transport

Author: Morton H. Friedman

Publisher: Springer Science & Business Media

Published: 2008-12-15

Total Pages: 520

ISBN-13: 0387792406

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Focus, Organization, and Content This book, like the first edition, deals with the mass transport processes that take place in living systems, with a focus on the normal behavior of eukaryotic cells and the - ganisms they constitute, in their normal physiological environment. As a consequence of this focus, the structure and content of the book differ from those of traditional transport texts. We do not start with the engineering principles of mass transport (which are well presented elsewhere) and then seek biological applications of these principles; rather, we begin with the biological processes themselves, and then - velop the models and analytical tools that are needed to describe them. This approach has several consequences. First of all, it drives the content of the text in a direction distinctively different from conventional transport texts. This is - cause the tools and models needed to describe complex biological processes are often different from those employed to describe more well-characterized inanimate systems. Many biological processes must still be described phenomenologically, using me- odologies like nonequilibrium thermodynamics. Simple electrical analogs employing a paucity of parameters can be more useful for characterization and prediction than complex theories based on the behavior of more well-defined systems on a laboratory bench. By allowing the biology to drive the choice of analysis tools and models, the latter are consistently presented in the context of real biological systems, and analysis and biology are interwoven throughout.


Principles and Models of Biological Transport

Principles and Models of Biological Transport

Author: Morton H. Friedman

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 274

ISBN-13: 3662024675

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This text is designed for a first course in biological mass transport, and the material in it is presented at a level that is appropriate to advanced undergraduates or early graduate level students. Its orientation is somewhat more physical and mathematical than a biology or standard physiology text, reflecting its origins in a transport course that I teach to undergraduate (and occasional graduate) biomedical engineering students in the Whiting School of Engineering at Johns Hopkins. The audience for my cours- and presumably for this text - also includes chemical engineering undergraduates concentrating in biotechnology, and graduate students in biophysics. The organization of this book differs from most texts that at tempt to present an engineering approach to biological transport. What distinguishes biological transport from other mass transfer processes is the fact that biological transport is biological. Thus, we do not start with the engineering principles of mass transport (which are well presented elsewhere) and then seek biological ap plications of these principles; rather, we begin with the biological processes themselves, and then develop the tools that are needed to describe them. As a result, more physiology is presented in this text than is often found in books dealing with engineering applica tions in the life sciences.


Modeling of Microscale Transport in Biological Processes

Modeling of Microscale Transport in Biological Processes

Author: Sid M. Becker

Publisher: Academic Press

Published: 2017-01-12

Total Pages: 0

ISBN-13: 9780128045954

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Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels.


Transport Modeling for Environmental Engineers and Scientists

Transport Modeling for Environmental Engineers and Scientists

Author: Mark M. Clark

Publisher: John Wiley & Sons

Published: 2011-09-20

Total Pages: 662

ISBN-13: 1118210867

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Transport Modeling for Environmental Engineers and Scientists, Second Edition, builds on integrated transport courses in chemical engineering curricula, demonstrating the underlying unity of mass and momentum transport processes. It describes how these processes underlie the mechanics common to both pollutant transport and pollution control processes.


Concepts of Biology

Concepts of Biology

Author: Samantha Fowler

Publisher:

Published: 2023-05-12

Total Pages: 0

ISBN-13: 9781739015503

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Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.


Membrane Transport Mechanism

Membrane Transport Mechanism

Author: Reinhard Krämer

Publisher: Springer Science & Business Media

Published: 2014-03-13

Total Pages: 282

ISBN-13: 3642538398

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This book provides a molecular view of membrane transport by means of numerous biochemical and biophysical techniques. The rapidly growing numbers of atomic structures of transporters in different conformations and the constant progress in bioinformatics have recently added deeper insights. The unifying mechanism of energized solute transport across membranes is assumed to consist of the conformational cycling of a carrier protein to provide access to substrate binding sites from either side of a cellular membrane. Due to the central role of active membrane transport there is considerable interest in deciphering the principles of one of the most fundamental processes in nature: the alternating access mechanism. This book brings together particularly significant structure-function studies on a variety of carrier systems from different transporter families: Glutamate symporters, LeuT-like fold transporters, MFS transporters and SMR (RND) exporters, as well as ABC-type importers. The selected examples impressively demonstrate how the combination of functional analysis, crystallography, investigation of dynamics and computational studies has made it possible to create a conclusive picture or more precisely, “a molecular movie”. Although we are still far from a complete molecular description of the alternating access mechanism, remarkable progress has been made from static snapshots towards membrane transport dynamics.


Cell Culture Models of Biological Barriers

Cell Culture Models of Biological Barriers

Author: Claus-Michael Lehr

Publisher: CRC Press

Published: 2002-08-08

Total Pages: 653

ISBN-13: 1134473443

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Over the past ten years several sophisticated in vitro test systems based on epithelial cell cultures have been introduced in the field of drug delivery. These models have been found to be very useful in characterizing the permeability of drugs across epithelial tissues, and in studying formulations or carrier systems for improved drug delivery and


Cellular Biophysics and Modeling

Cellular Biophysics and Modeling

Author: Greg Conradi Smith

Publisher: Cambridge University Press

Published: 2019-03-14

Total Pages: 395

ISBN-13: 1107005361

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What every neuroscientist should know about the mathematical modeling of excitable cells, presented at an introductory level.


Chemical Fate and Transport in the Environment

Chemical Fate and Transport in the Environment

Author: Harold F. Hemond

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 351

ISBN-13: 1483288641

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Chemical Fate and Transport in the Environment is a textbook for upper division undergraduate and graduate students studying environmental sciences in engineering, hydrology, chemistry, and other related disciplines. It covers the fundamental principles of mass transport and chemical partitioning, and the transformation of substances in surface water, in groundwater or subsurface environments, and in the atmosphere. Three major areas-surface water, ground water, and air-are covered, with descriptive overviews for each area. Each major section begins by describing environment: its controlling physical, chemical, and biological processes. The book also contains examples of common environmental problems and includes problem sets at the end of each chapter.Text that has been developed from a course taught at MITBroad-based coverage of the environmental sciencesA more rigorous treatment of transport than found in other textsExercise sets at the end of each chapterExamples of current environmental problems fully integrated into the textAmple references for access to the primary literatureNumerous illustrations throughout