Failure in R&D efforts are fairly common and with many factors that contribute to the outcome. This book focuses on the role of principal investigators (PIs) in R&D project failures and provides a theoretical model explaining how firm characteristics, including those of the PIs, impact the probability of failure. The theoretical model also serves as a structural form model to motivate the empirical analysis which assesses the probability of failure in small technology-based firms. The author uses data from the U.S. Department of Energy’s (DOE) Small Business Innovation Research (SBIR) program to build a new and informative tool to assess R&D projects and demonstrate the strengths of the theoretical model. The association between PIs and R&D failure not only provides insights that can have a downstream impact to economic growth, but it can also provide policymakers with valuable information to aid decisions in allocating funds for R&D.
Principal-investigator (PI) Earth science missions are small, focused science projects involving relatively small spacecraft. The selected PI is responsible for the scientific and programmatic success of the entire project. A particular objective of PI-led missions has been to help develop university-based research capacity. Such missions, however, pose significant challenges that are beyond the capabilities of most universities to manage. To help NASA's Office of Earth Science determine how best to address these, the NRC carried out an assessment of key issues relevant to the success of university-based PI-led Earth observation missions. This report presents the result of that study. In particular, the report provides an analysis of opportunities to enhance such missions and recommendations about whether and, if so, how they should be used to build university-based research capabilities.
If you want your startup to succeed, you need to understand why startups fail. “Whether you’re a first-time founder or looking to bring innovation into a corporate environment, Why Startups Fail is essential reading.”—Eric Ries, founder and CEO, LTSE, and New York Times bestselling author of The Lean Startup and The Startup Way Why do startups fail? That question caught Harvard Business School professor Tom Eisenmann by surprise when he realized he couldn’t answer it. So he launched a multiyear research project to find out. In Why Startups Fail, Eisenmann reveals his findings: six distinct patterns that account for the vast majority of startup failures. • Bad Bedfellows. Startup success is thought to rest largely on the founder’s talents and instincts. But the wrong team, investors, or partners can sink a venture just as quickly. • False Starts. In following the oft-cited advice to “fail fast” and to “launch before you’re ready,” founders risk wasting time and capital on the wrong solutions. • False Promises. Success with early adopters can be misleading and give founders unwarranted confidence to expand. • Speed Traps. Despite the pressure to “get big fast,” hypergrowth can spell disaster for even the most promising ventures. • Help Wanted. Rapidly scaling startups need lots of capital and talent, but they can make mistakes that leave them suddenly in short supply of both. • Cascading Miracles. Silicon Valley exhorts entrepreneurs to dream big. But the bigger the vision, the more things that can go wrong. Drawing on fascinating stories of ventures that failed to fulfill their early promise—from a home-furnishings retailer to a concierge dog-walking service, from a dating app to the inventor of a sophisticated social robot, from a fashion brand to a startup deploying a vast network of charging stations for electric vehicles—Eisenmann offers frameworks for detecting when a venture is vulnerable to these patterns, along with a wealth of strategies and tactics for avoiding them. A must-read for founders at any stage of their entrepreneurial journey, Why Startups Fail is not merely a guide to preventing failure but also a roadmap charting the path to startup success.
This issue of Heart Failure Clinics, edited by Drs. Wilbert Aronow and Ali Ahmed, will cover a wide array of topics related to Heart Failure in Older Adults. Subjects covered include, but are not limited to: Epidemiology, Pathophysiology, and Prognosis of Heart Failure in the Older Adult; DEFEAT Heart Failure: Clinical Manifestations, Diagnostic Assessment, and Etiology of Geriatric Heart Failure; Heart Failure with Preserved Ejection Fraction in the Older Adult; Heart Failure—Complicating Acute Myocardial Infarction; Interventional Therapies for Heart Failure in the Older Adult; Cardiac Resynchronization Therapy for Treatment of Heart Failure in the Older Adult; and Left Ventricular Assist Devices in Treatment of Heart Failure in the Older Adult, among others.
