Primary Bone Tumors and Tumorous Conditions in Children

Primary Bone Tumors and Tumorous Conditions in Children

Author: Claus-Peter Adler

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 272

ISBN-13: 1447119517

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We welcome the publication of this volume, which discusses the diagnosis of bone tumours with particular reference to children and adolescents. As founder members of the International Skeletal Society we are delighted to learn that the book had its inception at one of the Society's meetings. It reflects, moreover, the combined presentation of radiological and pathological diagnostic information which has been such a feature of the meetings of the International Skeletal Society. We commend it to all readers with an interest in tumours of the skeleton. Hubert A. Sissons Ronald O. Murray Preface The diagnosis of primary bone tumors is often difficult. There are several reasons for this. As primary bone tumors are rare in childhood, practitioners in a number of pediatric subspecialties are not familiar with them. The clinical symptoms and signs are often elusive, the biochemical investigations usually normal and the radio graphic features often uncharacteristic. Even the pathologist, who is the final step in arriving at the proper diagnosis and who has all the available clinical, biochemical and radiographic data, may encounter difficulties. A good tissue sample is the basis for microscopic investigation. However, bone tumors often show an extreme variety of structures which confuse even experienced bone pathologists. Therefore, histo pathologic analysis must take into account all available clinical, biochemical and radiographic data. The close cooperation of the pathologist with clinicians and, especially, radiologists is of the utmost importance.


Pediatric and Adolescent Osteosarcoma

Pediatric and Adolescent Osteosarcoma

Author: Norman Jaffe

Publisher: Springer Science & Business Media

Published: 2010-03-10

Total Pages: 591

ISBN-13: 1441902848

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Pediatric and Adolescent Osteosarcoma provides a historical review of the nature of osteosarcoma and the conflict that accompanied the introduction of adjuvant therapy for osteosarcoma culminating in accepted and prevailing methods of current therapy. It outlines concepts in Epidemiology and Etiology, and provides chapters on pathology and radiologic characteristics of osteosarcoma, surgical therapy tailored specifically for treatment of primary tumors in pediatric/adolescent age group, treatment of pulmonary and extra pulmonary metastases and complications, as well as the role of radiation therapy. The volume concludes with a review of differences and similarities in the management of osteosarcoma in adults as compared to pediatrics / adolescents and new laboratory and animal investigations currently in progress to develop effective diagnostic and therapeutic approaches to improve the outcome. In essence the scope and intensive coverage of the book provides a historical perspective of the advances made over the past 30 years and emerging concepts and prospects for new diagnostic and therapeutic approaches. This is based upon past experiences and new discoveries. It also provides a unique opportunity for pediatric and adult medical oncologists, physicians in training, orthopedic surgeons, pathologists, radiologists, radiotherapists, oncology nurses and allied professionals involved in the care of pediatric/adolescent patients with osteosarcoma to become acquainted with prevailing methods of treatment and new and evolving concepts and developments.


Malignant Pediatric Bone Tumors - Treatment & Management

Malignant Pediatric Bone Tumors - Treatment & Management

Author: Timothy P. Cripe

Publisher: Springer

Published: 2015-07-13

Total Pages: 313

ISBN-13: 3319180991

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This book describes in detail current best practice in the diagnosis and treatment of malignant pediatric bone tumors and also discusses other important aspects of management. Clinical assessment, the role of different imaging modalities and choice of biopsy procedure are explained and an individual chapter is devoted to diagnostic pathology. The treatment-oriented chapters offer in-depth descriptions of chemotherapeutic regimens, radiation therapy, limb-salvage options and amputation-related issues and in addition consider the approach to lung nodules, the role of biomarkers, off-therapy monitoring and the treatment of relapse. Psychosocial impacts and needs are addressed and guidance provided on nursing during treatment and rehabilitation following orthopaedic surgery. Closing chapters evaluate emerging therapies and discuss disparate aspects of survivorship. The authors are acknowledged experts and include many contributors from the Nationwide Children’s Hospital, a leading pediatric care facility in the United States.


Bone Cancer

Bone Cancer

Author: Heather Hasan

Publisher: The Rosen Publishing Group, Inc

Published: 2009-01-15

Total Pages: 67

ISBN-13: 1435857011

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Thoroughly researched and reviewed by an expert oncologist, this book looks closely at bone cancer, a disease that affects mostly children and adolescents. The author clearly explains the various types of bone cancer before discussing individual bone cancer risk factors, including genetic factors. She then goes into a detailed discussion of diagnosis and treatment of the disease. The final chapter examines improved surgical techniques that have led to fewer amputations as well as the technological advances in prosthetics that have greatly improved the lives of bone cancer survivors.


Bone and Soft Tissue Pathology

Bone and Soft Tissue Pathology

Author: Andrew L. Folpe, MD

Publisher: Elsevier Health Sciences

Published: 2009-08-04

Total Pages: 477

ISBN-13: 0443066884

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Bone and Soft Tissue Pathology: A Volume in the Diagnostic Pathology Series, by Andrew L. Folpe, MD and Carrie Y. Inwards, MD, packs today's most essential bone and soft tissue pathology know-how into a compact, high-yield format! The book's pragmatic, well-organized approach-complemented by abundant full-color, high-quality illustrations and at-a-glance tables-makes it easy to access the information you need to quickly and accurately identify pathology specimens. Best of all, Expert Consult functionality provides online access to the full text of the book, downloadable illustrations for your personal use, and more. The result is a practical, affordable reference for study and review as well as for everyday clinical practice. Includes access to the complete contents online, fully searchable, downloadable illustrations for your personal use, and more, allowing you to consult the text a quick, convenient manner. Reviews normal histology before examining abnormal findings, enabling you to conveniently compare their characteristics in one place at one time. Covers both neoplastic and non-neoplastic conditions of bone and soft tissue to equip you to meet a wide range of diagnostic challenges. Uses a consistent, user-friendly format to explore each entity's clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnoses, and prognostic and therapeutic considerations...making it easy to locate specific information on a particular entity. Features abundant boxes and tables throughout that enhance the presentation and accessibility of the material. Offers nearly 1,000 full-color, high-quality illustrations that demonstrate the key features of a wide variety of pathologic lesions to facilitate greater accuracy in identification of specimens. The Foundations in Diagnostic Pathology Series answers the call for fresh, affordable, and easy-to-use guidance. Each region-specific volume provides all of the most essential information on the pathologic entities encountered in practice. Series Editor: John R. Goldblum, MD, FACP, FASCP, FACG Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.


Bone Cancer

Bone Cancer

Author: Dominique Heymann

Publisher: Elsevier

Published: 2014-09-04

Total Pages: 730

ISBN-13: 0124167284

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Bone Cancer, Second Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases – from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases. - Presents a comprehensive, translational source for all aspects of primary bone cancer and bone metastases in one reference work - Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system - Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases - Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays


Surgery of the Pelvic and Sacral Tumor

Surgery of the Pelvic and Sacral Tumor

Author: Wei Guo

Publisher: Springer Nature

Published: 2020-06-03

Total Pages: 266

ISBN-13: 9402419454

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This book introduces the current state of surgical treatment in this particular location-sacrum and pelvis, presenting progress and innovation, describing in detail the related procedures. The book comprises three main parts, pelvic, sacral and typical cases. In each part, chapters are organized in a parallel fashion, with general considerations, surgical approaches and commonly used procedures. This helps to illustrate and detail the surgical techniques involved. This book is valuable for surgeons dealing with this challenging disease. Additionally, it summarizes and reinforces the previous knowledge of techniques in this field.