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Author: Mark Kirk
Publisher: ASTM International
Published: 2004
Total Pages: 168
ISBN-13: 080313472X
DOWNLOAD EBOOKNine papers from a November 2001 American Society for Testing and Materials symposium devoted to prediction of fundamental material behavior and structural response under a range of load conditions are presented by Kirk (U.S. Nuclear and Regulatory Commission) and Natishan (Phoenix Engineering Assoc
Author: Max Kuhn
Publisher: Springer Science & Business Media
Published: 2013-05-17
Total Pages: 595
ISBN-13: 1461468493
DOWNLOAD EBOOKApplied Predictive Modeling covers the overall predictive modeling process, beginning with the crucial steps of data preprocessing, data splitting and foundations of model tuning. The text then provides intuitive explanations of numerous common and modern regression and classification techniques, always with an emphasis on illustrating and solving real data problems. The text illustrates all parts of the modeling process through many hands-on, real-life examples, and every chapter contains extensive R code for each step of the process. This multi-purpose text can be used as an introduction to predictive models and the overall modeling process, a practitioner’s reference handbook, or as a text for advanced undergraduate or graduate level predictive modeling courses. To that end, each chapter contains problem sets to help solidify the covered concepts and uses data available in the book’s R package. This text is intended for a broad audience as both an introduction to predictive models as well as a guide to applying them. Non-mathematical readers will appreciate the intuitive explanations of the techniques while an emphasis on problem-solving with real data across a wide variety of applications will aid practitioners who wish to extend their expertise. Readers should have knowledge of basic statistical ideas, such as correlation and linear regression analysis. While the text is biased against complex equations, a mathematical background is needed for advanced topics.
Author: M. T. Kirk
Publisher:
Published: 2003
Total Pages: 0
ISBN-13:
DOWNLOAD EBOOKAuthor: Ramesh Talreja
Publisher: Cambridge University Press
Published: 2012-06-07
Total Pages: 315
ISBN-13: 0521819423
DOWNLOAD EBOOKBringing together materials mechanics and modelling, this book provides a complete guide to damage mechanics of composite materials for engineers.
Author: Pieter Kubben
Publisher: Springer
Published: 2018-12-21
Total Pages: 219
ISBN-13: 3319997130
DOWNLOAD EBOOKThis open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience.
Author: Preetanshu Pandey
Publisher: Woodhead Publishing
Published: 2016-09-26
Total Pages: 465
ISBN-13: 0081001800
DOWNLOAD EBOOKThe use of modeling and simulation tools is rapidly gaining prominence in the pharmaceutical industry covering a wide range of applications. This book focuses on modeling and simulation tools as they pertain to drug product manufacturing processes, although similar principles and tools may apply to many other areas. Modeling tools can improve fundamental process understanding and provide valuable insights into the manufacturing processes, which can result in significant process improvements and cost savings. With FDA mandating the use of Quality by Design (QbD) principles during manufacturing, reliable modeling techniques can help to alleviate the costs associated with such efforts, and be used to create in silico formulation and process design space. This book is geared toward detailing modeling techniques that are utilized for the various unit operations during drug product manufacturing. By way of examples that include case studies, various modeling principles are explained for the nonexpert end users. A discussion on the role of modeling in quality risk management for manufacturing and application of modeling for continuous manufacturing and biologics is also included. Explains the commonly used modeling and simulation tools Details the modeling of various unit operations commonly utilized in solid dosage drug product manufacturing Practical examples of the application of modeling tools through case studies Discussion of modeling techniques used for a risk-based approach to regulatory filings Explores the usage of modeling in upcoming areas such as continuous manufacturing and biologics manufacturingBullet points
Author: Phillip R. Westmoreland
Publisher: Springer Science & Business Media
Published: 2013-04-17
Total Pages: 596
ISBN-13: 9401707650
DOWNLOAD EBOOKComputational molecular and materials modeling has emerged to deliver solid technological impacts in the chemical, pharmaceutical, and materials industries. It is not the all-predictive science fiction that discouraged early adopters in the 1980s. Rather, it is proving a valuable aid to designing and developing new products and processes. People create, not computers, and these tools give them qualitative relations and quantitative properties that they need to make creative decisions. With detailed analysis and examples from around the world, Applying Molecular and Materials Modeling describes the science, applications, and infrastructures that have proven successful. Computational quantum chemistry, molecular simulations, informatics, desktop graphics, and high-performance computing all play important roles. At the same time, the best technology requires the right practitioners, the right organizational structures, and - most of all - a clearly understood blend of imagination and realism that propels technological advances. This book is itself a powerful tool to help scientists, engineers, and managers understand and take advantage of these advances.
Author: Mashroor Shafat Nitol
Publisher:
Published: 2021
Total Pages: 0
ISBN-13:
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Author: J.-P. Caliste
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 406
ISBN-13: 3642722075
DOWNLOAD EBOOKJ.-P. CALISTE, A. TRUYOL AND J. WESTBROOK The Series, "Data and Knowledge in a Changing World", exemplifies CODATA's primary purpose of collecting, from widely different fields, a wealth of information on efficient exploitation of data for progress in science and technology and making that information available to scientists and engineers. A separate and complementary CODATA Reference Series will present Directories of compiled and evaluated data and Glossaries of data-related terms. The present book "Thermodynamic Modeling and Materials Data Engineering" discusses thermodynamic, structural, systemic and heuristic approaches to the modeling of complex materials behavior in condensed phases, both fluids and solids, in order to evaluate their potential applications. Itwas inspired by the Symposium on "Materials and Structural Properties" held during the 14th International CODATA Conference in Chambery, France. The quality of the contributions to this Symposium motivated us to present" a coherent book of interest to the field. Updated contributions inspired by Symposium discussions and selections from other CODATA workshops concerning material properties data and Computer Aided Design combine to highlight the complexity of material data issues on experimental, theoretical and simulation levels Articles were selected for their pertinence in three areas. Complex data leading to interesting developments and tools such as: • new developments in state equations and their applications, • prediction and validation of physical and energy data by group correlations for pure compounds, • modeling and prediction of mixture properties.
Author: Bahram Farahmand
Publisher: Springer Science & Business Media
Published: 2009-06-29
Total Pages: 420
ISBN-13: 0387959246
DOWNLOAD EBOOKThematerialsusedinmanufacturingtheaerospace,aircraft,automobile,andnuclear parts have inherent aws that may grow under uctuating load environments during the operational phase of the structural hardware. The design philosophy, material selection, analysis approach, testing, quality control, inspection, and manufacturing are key elements that can contribute to failure prevention and assure a trouble-free structure. To have a robust structure, it must be designed to withstand the envir- mental load throughout its service life, even when the structure has pre-existing aws or when a part of the structure has already failed. If the design philosophy of the structure is based on the fail-safe requirements, or multiple load path design, partial failure of a structural component due to crack propagation is localized and safely contained or arrested. For that reason, proper inspection technique must be scheduled for reusable parts to detect the amount and rate of crack growth, and the possible need for repairing or replacement of the part. An example of a fail-sa- designed structure with crack-arrest feature, common to all aircraft structural parts, is the skin-stiffened design con guration. However, in other cases, the design p- losophy has safe-life or single load path feature, where analysts must demonstrate that parts have adequate life during their service operation and the possibility of catastrophic failure is remote. For example, all pressurized vessels that have single load path feature are classi ed as high-risk parts. During their service operation, these tanks may develop cracks, which will grow gradually in a stable manner.
