Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas
Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas

Author: National Research Council

Publisher: National Academies Press

Published: 2012-09-24

Total Pages: 132

ISBN-13: 0309257824

DOWNLOAD EBOOK

Safeguarding U.S. agriculture from foreign animal diseases and protecting our food system require cutting-edge research and diagnostic capabilities. The Department of Homeland Security (DHS) and the U.S. Department of Agriculture (USDA) have embarked on an important mission to replace the aging Plum Island Animal Disease Center (PIADC) with a new facility, the National Bio- and Agro-Defense Facility (NBAF). When operational, this new facility would be the world's fourth biosafety level-4 laboratory capable of large animal research. It would serve as a critical world reference laboratory for identifying emerging and unknown disease threats, and would thus be a critical asset in securing the future health, wealth, and security of the nation. DHS selected Manhattan, Kansas, as the site for the new NBAF after an extensive site-selection process that involved an environmental impact statement. The Government Accountability Office (GAO) raised concerns about DHS's analysis of the potential spread of foot-and-mouth disease virus (FMDv), one of the most serious foreign animal disease threats. Congress directed DHS to conduct a site-specific risk assessment (SSRA) for the NBAF, instructed the National Research Council (NRC) to independently evaluate the SSRA, and prohibited obligation of NBAF construction funds until the NRC review was complete. Congress mandated that DHS revise its SSRA to address shortcomings of the 2010 SSRA, directed the NRC to evaluate the updated SSRA (uSSRA), and again prohibited obligation of construction funds until the completion of the second review. The scope for both of these SSRA reports addressed accidental release of pathogens from the NBAF in Manhattan, Kansas and excluded terrorist acts and malicious threats from its risk assessments. Evaluation of the Updated Site-Specific Risk Assessment for the National Bio- and Agro-Defense Facility in Manhattan, Kansas is the evaluation of the final uSSRA.

Evaluation of a Site-Specific Risk Assessment for the Department of Homeland Security's Planned National Bio- and Agro-Defense Facility in Manhattan, Kansas
Evaluation of a Site-Specific Risk Assessment for the Department of Homeland Security's Planned National Bio- and Agro-Defense Facility in Manhattan, Kansas

Author: National Research Council

Publisher: National Academies Press

Published: 2011-01-02

Total Pages: 146

ISBN-13: 0309162815

DOWNLOAD EBOOK

Congress requested that the U.S. Department of Homeland Security (DHS) produce a site-specific biosafety and biosecurity risk assessment (SSRA) of the proposed National Bio- and Agro-Defense Facility (NBAF) in Manhattan, Kansas. The laboratory would study dangerous foreign animal diseases-including the highly contagious foot-and-mouth disease (FMD), which affects cattle, pigs, deer, and other cloven-hoofed animals-and diseases deadly to humans that can be transmitted between animals and people. Congress also asked the Research Council to review the validity and adequacy of the document. Until these studies are complete, Congress has withheld funds to build the NBAF. Upon review of the DHS assessment, the National Research Council found "several major shortcomings." Based on the DHS risk assessment, there is nearly a 70 percent chance over the 50-year lifetime of the facility that a release of FMD could result in an infection outside the laboratory, impacting the economy by estimates of $9 billion to $50 billion. The present Research Council report says the risks and costs of a pathogen being accidently released from the facility could be significantly higher. The committee found that the SSRA has many legitimate conclusions, but it was concerned that the assessment does not fully account for how a Biosafety-Level 3 Agriculture and Biosafety-Level 4 Pathogen facility would operate or how pathogens might be accidently released. In particular, the SSRA does not include important operation risks and mitigation issues, such as the risk associated with the daily cleaning of large animal rooms. It also fails to address risks that would likely increase the chances of an FMD leak or of the disease's spread after a leak, including the NBAF's close proximity to the Kansas State University College of Veterinary Medicine clinics and KSU football stadium or personnel moving among KSU facilities.

A Guide to Clinical Management and Public Health Response for Hand, Foot, and Mouth Disease (HFMD)
A Guide to Clinical Management and Public Health Response for Hand, Foot, and Mouth Disease (HFMD)

Author: WHO Regional Office for the Western Pacific

Publisher:

Published: 2011

Total Pages: 0

ISBN-13: 9789290615255

DOWNLOAD EBOOK

Hand, foot and mouth disease (HFMD) is a common infectious disease caused by a group of enteroviruses, including coxsackievirus A16 (CA16) and enterovirus 71 (EV71). Over the last decade, many outbreaks of HFMD have been reported in countries of the Western Pacific Region. HFMD caused by EV71 is of particular concern because of the increased number of deaths associated with infection. Until now, there has been little guidance on HFMD caused by EV71. This publication provides practical support for the treatment, prevention and control of HFMD based on the most recent scientific literature and the current understanding and experiences of international experts. It is intended as a resource for both clinicians working with HFMD cases on a regular basis and for public health personnel who are responsible for preventing and responding to outbreaks of HFMD.

National Economic Impact Analysis of Terrorist Attacks and Natural Disasters
National Economic Impact Analysis of Terrorist Attacks and Natural Disasters

Author: Harry W. Richardson

Publisher: Edward Elgar Publishing

Published: 2014-11-28

Total Pages: 293

ISBN-13: 1783475862

DOWNLOAD EBOOK

øA unique contribution towards mitigation is offered in this book, which develops a national economic impact model to estimate the effects of simulated terrorist attacks and real world natural disasters on individual US States and economic sectors. The

Bioterrorism
Bioterrorism

Author: H. T. Banks

Publisher: SIAM

Published: 2003-01-01

Total Pages: 247

ISBN-13: 0898715490

DOWNLOAD EBOOK

Collects the detailed contributions of selected groups of experts from the fields of biostatistics, control theory, epidemiology, and mathematical biology who have engaged in the development of frameworks, models, and mathematical methods needed to address some of the pressing challenges posed by acts of terror.