This guidance is an update of WHO global influenza preparedness plan: the role of WHO and recommendations for national measures before and during pandemics, published March 2005 (WHO/CDS/CSR/GIP/2005.5).
From the Pulitzer Prize–winning author of The Looming Tower, and the pandemic novel The End of October: an unprecedented, momentous account of Covid-19—its origins, its wide-ranging repercussions, and the ongoing global fight to contain it "A book of panoramic breadth ... managing to surprise us about even those episodes we … thought we knew well … [With] lively exchanges about spike proteins and nonpharmaceutical interventions and disease waves, Wright’s storytelling dexterity makes all this come alive.” —The New York Times Book Review From the fateful first moments of the outbreak in China to the storming of the U.S. Capitol to the extraordinary vaccine rollout, Lawrence Wright’s The Plague Year tells the story of Covid-19 in authoritative, galvanizing detail and with the full drama of events on both a global and intimate scale, illuminating the medical, economic, political, and social ramifications of the pandemic. Wright takes us inside the CDC, where a first round of faulty test kits lost America precious time . . . inside the halls of the White House, where Deputy National Security Adviser Matthew Pottinger’s early alarm about the virus was met with confounding and drastically costly skepticism . . . into a Covid ward in a Charlottesville hospital, with an idealistic young woman doctor from the town of Little Africa, South Carolina . . . into the precincts of prediction specialists at Goldman Sachs . . . into Broadway’s darkened theaters and Austin’s struggling music venues . . . inside the human body, diving deep into the science of how the virus and vaccines function—with an eye-opening detour into the history of vaccination and of the modern anti-vaccination movement. And in this full accounting, Wright makes clear that the medical professionals around the country who’ve risked their lives to fight the virus reveal and embody an America in all its vulnerability, courage, and potential. In turns steely-eyed, sympathetic, infuriated, unexpectedly comical, and always precise, Lawrence Wright is a formidable guide, slicing through the dense fog of misinformation to give us a 360-degree portrait of the catastrophe we thought we knew.
Pandemics. The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle. In Pandemics: What Everyone Needs to Know®, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts. Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know® series. What Everyone Needs to Know® is a registered trademark of Oxford University Press.
The plague organism (Yersinia pestis) killed an estimated 40% to 60% of all people when it spread rapidly through the Middle East, North Africa, and Europe in the fourteenth century: an event known as the Black Death. Previous research has shown, especially for Western Europe, how population losses then led to structural economic, political, and social changes. But why and how did the pandemic happen in the first place? When and where did it begin? How was it sustained? What was its full geographic extent? And when did it really end?
In recent public workshops and working group meetings, the Forum on Microbial Threats of the Institute of Medicine (IOM) has examined a variety of infectious disease outbreaks with pandemic potential, including those caused by influenza (IOM, 2005) and severe acute respiratory syndrome (SARS) (IOM, 2004). Particular attention has been paid to the potential pandemic threat posed by the H5N1 strain of avian influenza, which is now endemic in many Southeast Asian bird populations. Since 2003, the H5N1 subtype of avian influenza has caused 185 confirmed human deaths in 11 countries, including some cases of viral transmission from human to human (WHO, 2007). But as worrisome as these developments are, at least they are caused by known pathogens. The next pandemic could well be caused by the emergence of a microbe that is still unknown, much as happened in the 1980s with the emergence of the human immunodeficiency virus (HIV) and in 2003 with the appearance of the SARS coronavirus. Previous Forum meetings on pandemic disease have discussed the scientific and logistical challenges associated with pandemic disease recognition, identification, and response. Participants in these earlier meetings also recognized the difficulty of implementing disease control strategies effectively. Ethical and Legal Considerations in Mitigating Pandemic Disease: Workshop Summary as a factual summary of what occurred at the workshop.
Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.
Pandemics can come in waves—like tidal waves. They change societies. They disrupt life. They end lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts. Most, but not all, bacteria are good for us. Some are truly horrific, including those that caused the bubonic, pneumonic, and septicemic plagues. And viruses and bacteria are always morphing, evolving, and changing, making them hard to treat. Plagues, Pandemics, and Viruses: From the Plague of Athens to Covid 19 is an enlightening, and sometimes frightening, recounting of the destruction wrought by disease, but it also looks at what man has done and can do to overcome even the deadliest and bleakest of contagions. More than two years in the making, author Heather E. Quinlan was deep into her research and writing when COVID hit. She quickly saw the similarities to plagues from the past. Plagues, Pandemics, and Viruses: From the Plague of Athens to Covid 19 not only covers the history, causes, medical treatments, human responses, and aftermath of the world’s biggest pandemics, but it also draws parallels to the present. It chronicles the diseases that have inflicted man throughout the millennia, including ... The differences (and similarities) between COVID-19 and other coronaviruses The bubonic plague/black plague, which wiped out 30% to 60% of Europe’s population The devastation to the indigenous population during the European colonization of the Americas The 1918 Spanish Flu, which did not come from Spain How disease “inspired” The Canterbury Tales, Wuthering Heights, the pop art of Keith Haring, and other art and literature AIDS’ “patient zero” How climate change will affect future pandemics The aftermath of various pandemics Several modern diseases making a comeback ... and much, much more. Along with investigating some of history’s most notorious pandemics and diseases, Plagues, Pandemics, and Viruses takes a look at human resilience and what we’ve learned from the past. It looks at how science, the medical community, and governments have conquered or mitigated most epidemics even before they can turn into pandemics. It reviews the science of pandemics, preventative measures, and medical interventions and it includes an exclusive interview with Dr. Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, as well as other experts in the medical community. Richly illustrated, it also has a helpful bibliography and extensive index. This invaluable resource is designed to help you understand, and protect you from, plagues, pandemics, epidemics, viruses, and disease!
A wide-ranging study that illuminates the connection between epidemic diseases and societal change, from the Black Death to Ebola This sweeping exploration of the impact of epidemic diseases looks at how mass infectious outbreaks have shaped society, from the Black Death to today. In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare. A multidisciplinary and comparative investigation of the medical and social history of the major epidemics, this volume touches on themes such as the evolution of medical therapy, plague literature, poverty, the environment, and mass hysteria. In addition to providing historical perspective on diseases such as smallpox, cholera, and tuberculosis, Snowden examines the fallout from recent epidemics such as HIV/AIDS, SARS, and Ebola and the question of the world’s preparedness for the next generation of diseases.
An eye-opening anthology from the bestselling editor of Histories of Nations, exploring how people around the globe have suffered and survived during plague and pandemic, from the ancient world to the present. Plague, pestilence, and pandemics have been a part of the human story from the beginning and have been reflected in art and writing at every turn. Humankind has always struggled with illness; and the experiences of different cities and countries have been compared and connected for thousands of years. Many great authors have published their eyewitness accounts and survivor stories of the great contagions of the past. When the great Muslim traveler Ibn Battuta visited Damascus in 1348 during the great plague, which went on to kill half of the population, he wrote about everything he saw. He reported, "God lightened their affliction; for the number of deaths in a single day at Damascus did not attain 2,000, while in Cairo it reached the figure of 24,000 a day." From the plagues of ancient Egypt recorded in Genesis to those like the Black Death that ravaged Europe in the Middle Ages, and from the Spanish flu of 1918 to the Covid-19 pandemic in our own century, this anthology contains fascinating accounts. Editor Peter Furtado places the human experience at the center of these stories, understanding that the way people have responded to disease crises over the centuries holds up a mirror to our own actions and experiences. Plague, Pestilence and Pandemic includes writing from around the world and highlights the shared emotional responses to pandemics: from rage, despair, dark humor, and heartbreak, to finally, hope that it may all be over. By connecting these moments in history, this book places our own reactions to the Covid-19 pandemic within the longer human story.