Placental Bed Disorders

Placental Bed Disorders

Author: Robert Pijnenborg

Publisher: Cambridge University Press

Published: 2010-06-03

Total Pages: 325

ISBN-13: 1139488686

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It is now recognized that defective placentation in the human is a cause of many pregnancy complications, such as spontaneous abortion, preterm labor and delivery, pre-eclampsia, intrauterine growth restriction, fetal death and abruptio placenta. These clinical disorders can often have long-term consequences into adulthood, causing cardiovascular disease, obesity and diabetes for the newborn as well as an increased risk of premature death in the mother. This is the first book to be entirely focused on the placental bed, bringing together the results of basic and clinical research in cell biology, immunology, endocrinology, pathology, genetics and imaging to consolidate in a single, informative source for investigators and clinicians. Its core aim is to explore new approaches and improve current clinical practice. This is essential reading for clinicians in obstetric, cardiovascular and reproductive medicine.


Placental Bed Vascular Disorders

Placental Bed Vascular Disorders

Author: Robert Pijnenborg

Publisher:

Published: 2014-05-14

Total Pages: 325

ISBN-13: 9780511750106

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"The role of the placental bed in normal pregnancy and its complications has been intensively investigated for 50 years, following the introduction of a technique for placental bed biopsy. It is now recognized that disorders of the maternal-fetal interface in humans have been implicated in a broad range of pathologic conditions, including spontaneous abortion, preterm labor, preterm premature rupture of membranes, pre-eclampsia, intrauterine growth restriction, abruptio placentae and fetal death"--Provided by publisher.


Vascular Biology of the Placenta

Vascular Biology of the Placenta

Author: Yuping Wang

Publisher: Biota Publishing

Published: 2017-06-23

Total Pages: 126

ISBN-13: 1615047514

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The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.


Placental Bed Vascular Disorders

Placental Bed Vascular Disorders

Author: Robert Pijnenborg

Publisher:

Published: 2010

Total Pages: 301

ISBN-13: 9780511742484

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"The role of the placental bed in normal pregnancy and its complications has been intensively investigated for 50 years, following the introduction of a technique for placental bed biopsy. It is now recognized that disorders of the maternal-fetal interface in humans have been implicated in a broad range of pathologic conditions, including spontaneous abortion, preterm labor, preterm premature rupture of membranes, pre-eclampsia, intrauterine growth restriction, abruptio placentae and fetal death"--Provided by publisher.


Vascular Dysfunction Beyond Pathological Pregnancies. An International Effort Addressed to Fill the Gaps in Latin America

Vascular Dysfunction Beyond Pathological Pregnancies. An International Effort Addressed to Fill the Gaps in Latin America

Author: Carlos Alonso Escudero

Publisher: Frontiers Media SA

Published: 2019-11-22

Total Pages: 136

ISBN-13: 2889632016

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Pregnancy is a physiologically stressful condition that generates a series of functional adaptations in the cardiovascular system. The impact of pregnancy on this system persists from conception beyond birth. Recent evidence suggests that vascular changes associated with pregnancy complications, such as preeclampsia; gestational diabetes; growth restriction; autoimmune diseases; among others, affect the function of the maternal and offspring vascular systems, after delivery and may be extended until adult life. Since the vascular system contributes to systemic homeostasis, defective development or function of blood vessels predisposes both mother and infant to future risk for chronic disease. In Latin American countries, like other low (LIC) and middle-income countries (MIC) worldwide, the rate of morbi-mortality due to both pregnancy complications and cardiovascular diseases have a higher incidence than in high-income countries (HIC). But, investigation in LIC and MIC, in particular in Latin America, still fall short of what would be expected considering the magnitude of those diseases. Although there are obvious deficiencies in terms of economies and scientific infrastructure between HIC and MIC or LIC, Latin American strength in terms of scientific productivity in this filed could be underestimated due to language limitation and publication in journals not indexed in major citation databases, resulting in low impact publications. As a result, we could speculate that potentially unique features of vascular disease associated to pregnancies complications can be unnoted in the global scientific community. Then, we would like to encourage researchers in vascular biology, in which, many groups in Latin America have contributed to both better understand vascular dysfunction associated to pregnancy diseases and show the gaps in the literature, to overcome this hidden effect of our scientific production. This effort also will homogenize clinical concepts and knowledge that may strength the scientific effort in Latin America.


Placental Vascularization and Blood Flow

Placental Vascularization and Blood Flow

Author: R.K. Miller

Publisher: Springer Science & Business Media

Published: 2013-03-13

Total Pages: 365

ISBN-13: 1461581095

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The optimal function of the placenta and thus fetal well being largely depends upon the integrity of both the fetal and maternal circulations of the placenta. Intense basic research concerned with placental vascularization and blood flow has been performed for the past 30 years, beginning with the classical morphological descriptions of the placental vessels by Boe (1953) and Arts (1961), as well as with the radioangiographic studies of maternal placental circulation in the human by Borell (1958) and in the rhesus monkey by Ramsey (1962). The scientific framework presented by these investigators has been filled and completed by numerous investigators, leading to more morphological details, functional considerations, and pathological understanding. For an extended period of time, this research has been of primarily academic interest by increasing our insights into one important system of the placenta, yet having nearly no practical importance. Recently, this situation has changed dramatically: in vitro studies of the isolated, dually perfused human placenta and in vivo studies of placental circulation for diagnostic purposes have raised an enormous interest in basic research data. New methods like Doppler Ultrasound and NMR became available. These technics have enabled the obstetrician to study fetal and placental hemodynamics in vivo. Meanwhile, such methods are becoming incorporated into the daily obstetrical routine, to some degree without an adequate background knowledge of placental vascularization and blood flow, since such experience is currently available to only a small group of experts.


Handbook of Placental Pathology

Handbook of Placental Pathology

Author: Ona Marie Faye-Petersen

Publisher: CRC Press

Published: 2005-11-13

Total Pages: 268

ISBN-13: 020348956X

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A user-friendly text, this book explores all the diagnostic challenges pathologists and obstetricians will face. Succinct and accessible, the text includes discussions of lesions associated with maternal thrombophilias, updates in disorders with challenging clinicopathologic features and pathogenesis. The new edition contains updated sections on co


Pathology of the Placenta

Pathology of the Placenta

Author: Steven H. Lewis

Publisher:

Published: 1999

Total Pages: 442

ISBN-13:

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Here's the completely revised, updated and expanded 2nd Edition of this definitive reference on placental pathology. Presents reliable, step-by-step guidance on placental examination techniques, and also examines infection and multiple gestations. This comprehensive edition features a new chapter on ultrasound, which provides critical antenatal information not available in pathology texts, and also features a chapter detailing the latest information on molecular biology.


Placental Adhesive Disorders

Placental Adhesive Disorders

Author: José Miguel Palacios-Jaraquemada

Publisher: Walter de Gruyter

Published: 2012-08-31

Total Pages: 172

ISBN-13: 3110282380

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Abnormal placental adhesive disorders are associated to massive hemorrhage and high maternal morbidity and mortality. The main risk factor for abnormal invasive placentation is the repeated cesarean, although other factors were identified. There are specific techniques to provide a high confidence diagnosis. However, precise skills must be acquired to recognize detailed diagnostic signs, to avoid common technical mistakes, and also to know when, how and why it is necessary to use each of them. Presurgical study provides diagnosis, extension and compromise of neighboring structures such as the bladder or the parametrium. Knowledge of placental invasion extension is needed to plan any resective surgery such as hysterectomy or one-step conservative surgery. Due to the fact that topography of the invaded area has direct relation with the specific arterial pedicles, a map of the invasion is required to know which type of proximal vascular control can be more effective. Leaving the placenta in situ seems to be the best option when resources or a skilled team are not available, but it requires intensive postoperative controls to detect infection, bleeding or coagulation disorders. Hysterectomy can be an easy solution for non-experimented operators; however, it is usually a very complicated procedure with demonstrated morbidity and mortality due to hemodynamic and hemostatic problems. This book gathers the latest knowledge in relation with the etiology, diagnosis, treatment and also the authors personal experience in more than 500 cases. All aspects of this condition have been analyzed to provide an accurate management, which includes vascular control, urology, anesthesia and hemodynamic management among others.