Pharmacological Effects of Ethanol on the Nervous System
Pharmacological Effects of Ethanol on the Nervous System

Author: Richard A. Deitrich

Publisher: CRC Press

Published: 1995-12-21

Total Pages: 482

ISBN-13: 9780849383892

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This book dissects the effects of ethanol on the major neurotransmitter systems affected by ethanol and correlates these actions with the behavioral consequences. The subject is approached first from the perspective of the neurochemical system and the behaviors resulting from ethanol's effects on that system. The behaviors themselves are discussed in later chapters. Some older theories of the effects of ethanol such as the membrane fluidization hypothesis are evaluated in light of new and updated information. Fetal Alcohol Syndrome (FAS) as well as the structural damage in the brain by long term ethanol exposure are also discussed.

The Pharmacology of Alcohol and Alcohol Dependence
The Pharmacology of Alcohol and Alcohol Dependence

Author: Henri Begleiter

Publisher: Oxford University Press, USA

Published: 1996

Total Pages: 544

ISBN-13: 9780195100945

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This is a comprehensive review of the pharmacological effects of alcohol and the mechanisms underlying the pathogenesis of alcoholism. The book draws on general pharmacology, neuropharmacology, and alcohol studies to explore its theme. The second volume in the ALCOHOL AND ALCOHOLISM series, it focuses on the pharmacologic mechanisms underlying the development of alcoholism. The first section on basic pharmacology is concerned with those aspects that are common to all of alcohol's effects. These include pharmacokinetics, general metabolism, and cross-tolerance. The second section on neuropharmacology describes the effects of alcohol on various brain functions, including circulation and metabolism. The third section provides an in-depth review of the neurobiology of physical dependence, withdrawal, and physiological tolerance. The book as a whole gives a comprehensive and authoritative picture of the complex pharmacologic actions of alcohol, particularly on the nervous system. For clinicians and researchers in the field of alcohol and alcoholism, it will serve as a fundamental reference.

Animal Models of Cognitive Impairment
Animal Models of Cognitive Impairment

Author: Edward D. Levin

Publisher: CRC Press

Published: 2006-06-22

Total Pages: 395

ISBN-13: 1420004336

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The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairmen

The Neuropharmacology of Alcohol
The Neuropharmacology of Alcohol

Author: Kathleen A. Grant

Publisher: Springer

Published: 2019-03-27

Total Pages: 625

ISBN-13: 3319965239

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This volume gives an overview of new insights to alcohol pharmacology using DREADDs (Designer Receptors and Unraveling the Neuropharmacology of Alcohol). It examines which pharmacological principles should be applied to understanding DREADDs taking into account some very current research. Additionally, this book covers important topics under the heading of “experimental pharmacology” and alcohol.

Alcohol and the Nervous System
Alcohol and the Nervous System

Author: Edith V. Sullivan

Publisher: Elsevier

Published: 2014-10-08

Total Pages: 703

ISBN-13: 0444626220

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Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

The Nervous System
The Nervous System

Author: Walter S. Root

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 720

ISBN-13: 1483275825

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Physiological Pharmacology: A Comprehensive Treatise, Volume I: The Nervous System — Part A, Central Nervous System Drugs focuses on the influence of drugs on the functions of the central nervous system. The selection first offers information on absorption, distribution, and elimination and effects upon physiological systems. Discussions focus on factors that disturb normal sequence of uptake and elimination of volatile drugs; variations in distribution due to systemic effects of anesthetics; factors influencing the uptake of gases by tissues; and theories of general anesthesia. The book also ponders on alcohols, including alcohols acting on the central nervous system; effect of alcohols on and outside the central nervous system; and synergisms and antagonisms between alcohols and other drugs. The publication takes a look at sedatives and hypnotics, effects upon physiological systems, and analgesics and antipyretic drugs. The text also examines non-narcotic analgesics, tranquilizers, and diphenylmethane derivatives. The selection is a vital source of data for readers interested in the effects of drugs on the central nervous system.

The Pharmacology of Alcohol and Drugs of Abuse and Addiction
The Pharmacology of Alcohol and Drugs of Abuse and Addiction

Author: Norman S. Miller

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 359

ISBN-13: 1461230446

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This volume is intended for clinicians, researchers, residents, and students. The range is wide and the depth considerable for all the topics covered in the treatment of this timely and relevant subject. This book may serve equally well as a general introduction and a scholarly reference. Ultimately, it is designed to serve those patients suffering from abuse of and addiction to drugs and alcohol. The content and organization of the book flow from general concepts of abuse and addiction to specific details of the pharmacology of alcohol and drugs. Special chapters on topics not found in most other books, such as pharmacology of drug-drug interactions, abstinence, and prevention, are included. This book is written especially for the clinician interested in the pharma cology of alcohol and drugs of abuse and addiction. The pharmacology is integrated into a conceptual approach to diagnosis and treatment of alcohol and drug abuse and addiction. The form and style are didactic, critical as well as straightforward in presentation. Literature references from recent clinical research and basic research provide the foundation for the chapters throughout the book. Be cause the book is written by a clinician-researcher, the information is readily adaptable to clinical problems and research ideas. I would like to express my deep appreciation to Susan Newsom and Darlene Tucci for their invaluable technical assistance. Norman S. Miller vii Contents Preface ....................................................... vii CHAPTER 1 Introduction to the Pharmacological Effects of Alcohol and Drugs and Addiction on the Brain and Behavior .... . . . . . . . . . . . . . . . . . .. . . 1 . . . . . .

Development of the Central Nervous System
Development of the Central Nervous System

Author: Michael W. Miller

Publisher: Wiley-Liss

Published: 1992

Total Pages: 424

ISBN-13:

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Disseminates information pertaining to the normal and abnormal processes involved during the development of the central nervous system. The toxic effects of alcohol or opiate usage on development are explored by examining the clinical manifestations that appear in the children of substance-abusing mothers. Detailed coverage includes individual ontogenetic and developmental processes such as neural chemical differentiation, cell proliferation and migration.