Pharmaceutical Research Methodology & Bio-Statistics
Pharmaceutical Research Methodology & Bio-Statistics

Author: Subba Bayya Rao

Publisher: Pharmamed Press

Published: 2023-05

Total Pages: 0

ISBN-13: 9789395039345

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"Pharmaceutical Research Methodology and Bio-Statistics: Theory and Practice" is aimed in understanding the fundamental concepts of developing a research bent of mind by careful planning, execution, collection of data and analyzing for statistical significance. The book is aimed at B. Pharm, Pharm D, Pharm D (PB), M. Pharm, allied course students, researchers at the academic and industry levels, Ph. D scholars, policy makers, regulators etc. Key Features: - Distinguishing statistics and bio-statistics - How to identify a problem, plan for research and execute the idea - Chemical abstract literature search - Anatomy of a research paper - Compare and contrast of research proposal, research report, research paper, patent document, synopsis - Concept of meta-analysis to resolve research ambiguities - Data collection, cleansing, presenting - How to overcome missing data - Introduction to Probability, Permutations and Combinations - Parametric distributions - binomial, poisson, normal, chi-square, student 't', F distributions - Extra information on Bernoulli Distribution and Chebyshev's Theorem - Role of Type I and Type II errors, Power, sample size, confidence level, confidence interval, confidence limits - How to judge whether data upon analysis is statistical significant or not - Developing hypothesis as null, alternate and how to draw conclusion after conducting suitable statistical test - Non-parametric statistical test - Run, Sign, Wilcoxon Signed rank, Wilcoxon rank sum tests - Parametric, Non-parametric ANOVAs (1-way with multiple comparisons, 2-way, cross over, 3-way) - Step wise Parametric and non-parametric problem solving - Applications of linear regression and correlation coef ficient relating to pharmaceuticals - Appended with Multi-linear Regression Analysis (Mathematical and Excel Calculation)

Quantitative Methods in Pharmaceutical Research and Development
Quantitative Methods in Pharmaceutical Research and Development

Author: Olga V. Marchenko

Publisher: Springer Nature

Published: 2020-09-24

Total Pages: 445

ISBN-13: 3030485552

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This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.

Bayesian Methods in Pharmaceutical Research
Bayesian Methods in Pharmaceutical Research

Author: Emmanuel Lesaffre

Publisher: CRC Press

Published: 2020-04-15

Total Pages: 547

ISBN-13: 1351718673

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Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian Biostatistics conference was held, with the primary objective to stimulate the practical implementation of Bayesian statistics, and to promote the added-value for accelerating the discovery and the delivery of new cures to patients. This book is a synthesis of the conferences and debates, providing an overview of Bayesian methods applied to nearly all stages of research and development, from early discovery to portfolio management. It highlights the value associated with sharing a vision with the regulatory authorities, academia, and pharmaceutical industry, with a view to setting up a common strategy for the appropriate use of Bayesian statistics for the benefit of patients. The book covers: Theory, methods, applications, and computing Bayesian biostatistics for clinical innovative designs Adding value with Real World Evidence Opportunities for rare, orphan diseases, and pediatric development Applied Bayesian biostatistics in manufacturing Decision making and Portfolio management Regulatory perspective and public health policies Statisticians and data scientists involved in the research, development, and approval of new cures will be inspired by the possible applications of Bayesian methods covered in the book. The methods, applications, and computational guidance will enable the reader to apply Bayesian methods in their own pharmaceutical research.

Statistical Methodology in the Pharmaceutical Sciences
Statistical Methodology in the Pharmaceutical Sciences

Author: D. A. Berry

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 592

ISBN-13: 1482276860

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A state-of-the-art handbook of statistical analysis for use in the pharmaceutical industry. Areas covered in this reference/text include: bioavailability, repeated-measures designs, dose-response, population models, multicenter trials, handling dropouts, survival analysis, robust data analysis, cate

Introduction to Statistics in Pharmaceutical Clinical Trials
Introduction to Statistics in Pharmaceutical Clinical Trials

Author: Todd A. Durham

Publisher:

Published: 2008-01-01

Total Pages: 226

ISBN-13: 9780853697145

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All students of pharmaceutical sciences and clinical research need a solid knowledge and understanding of the nature, methods, application, and importance of statistics. Introduction to Statistics in Pharmaceutical Clinical Trials is an ideal introduction to statistics presented in the context of clinical trials conducted during pharmaceutical drug development. This novel approach both teaches the computational steps needed to conduct analyses and provides a conceptual understanding of how these analyses provide information that forms the rational basis for decision making throughout the drug development process.

Modern Issues and Methods in Biostatistics
Modern Issues and Methods in Biostatistics

Author: Mark Chang

Publisher: Springer Science & Business Media

Published: 2011-07-15

Total Pages: 316

ISBN-13: 144199842X

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Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.

Essential Statistical Methods for Medical Statistics
Essential Statistical Methods for Medical Statistics

Author: J. Philip Miller

Publisher: Elsevier

Published: 2010-11-08

Total Pages: 363

ISBN-13: 0444537384

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Essential Statistical Methods for Medical Statistics presents only key contributions which have been selected from the volume in the Handbook of Statistics: Medical Statistics, Volume 27 (2009). While the use of statistics in these fields has a long and rich history, the explosive growth of science in general, and of clinical and epidemiological sciences in particular, has led to the development of new methods and innovative adaptations of standard methods. This volume is appropriately focused for individuals working in these fields. Contributors are internationally renowned experts in their respective areas. - Contributors are internationally renowned experts in their respective areas - Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research - Methods for assessing Biomarkers, analysis of competing risks - Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs - Structural equations modelling and longitudinal data analysis

A Text Book for Pharmaceutical Research Methodology and Bio-Statistics
A Text Book for Pharmaceutical Research Methodology and Bio-Statistics

Author: Dr. Tirupati Rasala, Dr. Debasish Pradhan, Shubham Gupta, Dr Bandana Behera, Dr Shakti Prasad Pradhan

Publisher: Shashwat Publication

Published: 2024-05-29

Total Pages: 219

ISBN-13: 9360874582

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This book is specifically geared towards students in pharmacy programs and covers all the essential topics in research methodology, from the basics of research design to statistical analysis. It also includes a section on biostatistics, which is essential for pharmaceutical research. This book is a more general introduction to research methods, but it still has a lot to offer students in pharmacy programs. It covers a wide range of topics, including research design, data collection, data analysis, and scientific writing. This book will be a great resource for any student in a Masters in Pharmacy and Bachelors in Pharmacy programme.

Pharmaceutical Statistics Using SAS
Pharmaceutical Statistics Using SAS

Author: Alex Dmitrienko, Ph.D.

Publisher: SAS Institute

Published: 2007-02-07

Total Pages: 464

ISBN-13: 1629590304

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Introduces a range of data analysis problems encountered in drug development and illustrates them using case studies from actual pre-clinical experiments and clinical studies. Includes a discussion of methodological issues, practical advice from subject matter experts, and review of relevant regulatory guidelines.