Comprehensive Medicinal Chemistry III

Comprehensive Medicinal Chemistry III

Author:

Publisher: Elsevier

Published: 2017-07-19

Total Pages: 0

ISBN-13: 9780128032008

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Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs


Pharmaceutical Chemistry - Ii

Pharmaceutical Chemistry - Ii

Author: A. V. Kasture

Publisher: Pragati Books Pvt. Ltd.

Published: 2014-05

Total Pages: 388

ISBN-13: 9788185790206

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Introduction. Centrak Nervous System Stimulants. Antidepressants and Antinxienty Agent (Anxiolytic). Antipsychotic Agents and Hallucinogens. General Anaestetics. Hypnotics and Sedatives. Skeletal Muscle Relaxants. Tranquilizing Agents. Anticonvulsant Drugs. Analgesics (Narcotcs). Anpyertic Analgesics. Nonsteroidal Anti- Inflammatory Agents. Adrenergic Agents. Adrenergic Blocking Agents. Cardiovascular Agents. Histamines & Antihistaminic Agents. antitussives & Expectorants. Coagulants and Anticoagulants


Pharmaceutical Organic Chemistry-Iii

Pharmaceutical Organic Chemistry-Iii

Author: Pramod Nayanapalli

Publisher: Educreation Publishing

Published: 2019-02-20

Total Pages: 124

ISBN-13:

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PREFACE The main objective of writing this book for II B.Pharmacy, IV semester is to gain knowledge about stereochemical considerations are important in both isomerism. the relative three-dimensional orientation of the reacting particles at any time in the reaction. Concentrating on organic chemistry, early chapters deal mainly with definitions of terms such as chirality, enantiomers, diastereoisomers, meso type and racemization, complete with suitable examples to illustrate key concepts. Use of a polarimeter and associated definitions are described, together with two different conventions D, L and R, S and E, Z. Aspects of stereochemistry are explored through consideration of addition reactions to alkenes and carbonyl groups, nucleophilic substitution, and reactions (and interactions) involved in the resolution of racemic mixtures. The book also provide knowledge related to heterocyclic compounds their nomenclature preparations reactions basicity and aromaticity including applications of every heterocyclic nucleus that are mentioned according PCI syllabus were discussed. Some of the synthetic important named reactions and mechanism presented simple way for the easy understanding for students. Over this entire book help students to learn subject concept orient, to express well during respective university examination and get through examination successfully.


Practical Pharmaceutical Chemistry

Practical Pharmaceutical Chemistry

Author: A. H. Beckett

Publisher: A&C Black

Published: 1988-01-01

Total Pages: 630

ISBN-13: 9780485113235

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This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.


Pharmaceutical Chemistry

Pharmaceutical Chemistry

Author: Christine Bladon

Publisher: John Wiley & Sons

Published: 2002-04-03

Total Pages: 240

ISBN-13: 9780471496373

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Providing a broad introduction to the growing field, this book explores the way in which peptides, proteins, nucleic acids and carbohydrates used therapeutically. With help of numerous illustrations, it covers both the compounds and how therapeutics exert their influence throuhg an understanding of biological processes. * Includes the latest developments in the field * Covers the various strategies behind the development and production of a range of key clinically useful compounds * Focuses on the concepts and ideas of why compounds are developed as pharmaceuticals * Provides many examples and problems Invaluable to all students of chemistry, medicinal and pharmaceutical chemistry, pharmacy and pharmacology. Will also be of interest to researchers and professionals needing a concise, up-to-date account of this subject.


Essentials of Pharmaceutical Chemistry

Essentials of Pharmaceutical Chemistry

Author: Donald Cairns

Publisher: Pharmaceutical Press

Published: 2012

Total Pages: 321

ISBN-13: 0853699798

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An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems


Experiments in Pharmaceutical Chemistry, Second Edition

Experiments in Pharmaceutical Chemistry, Second Edition

Author: Charles Dickson

Publisher: CRC Press

Published: 2014-02-21

Total Pages: 162

ISBN-13: 1482225085

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Written by an author with more than 40 years of teaching experience in the field, Experiments in Pharmaceutical Chemistry, Second Edition responds to a critical classroom need for material on directed laboratory investigations in biological and pharmaceutical chemistry. This new edition supplies 75 experiments, expanding the range of topics to 22 major areas of pharmaceutical chemistry. These include biochemical groups, botanical classes important to pharmacy, and major drug classifications: Carbohydrates Lipids Proteins Enzymes Inorganics Vitamins Steroids Plant Acids Flavonoids Alkaloids Tannins Resins Glycosides Gums Balsams Volatile Oils Analgesics Anesthetics Sulfa Drugs (Sulfonamides) Psychotropic Drugs Antibiotics Nucleic Acids Sections contain introductions to basic concepts underlying the fields addressed and a specific bibliography relating to each field. Each experiment provides detailed instructions in a user-friendly format, and can be carried out, in most cases, without the need for expensive instrumentation. This comprehensive laboratory manual offers much-needed instructional material for teaching laboratory classes in pharmaceutical chemistry. The breadth of subject matter covered provides a variety of choices for structuring a laboratory course.


The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action

Author: Richard B. Silverman

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 650

ISBN-13: 0080513379

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Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization