Basic Science of PET Imaging

Basic Science of PET Imaging

Author: Magdy M. Khalil

Publisher: Springer

Published: 2016-11-07

Total Pages: 621

ISBN-13: 3319400703

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This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.


Basics of PET Imaging

Basics of PET Imaging

Author: Gopal B. Saha

Publisher: Springer Science & Business Media

Published: 2010-03-10

Total Pages: 244

ISBN-13: 1441908056

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This reference on the basics of PET and PET/CT imaging has been revised with concise chapters on PET fundamentals. The chapters include pertinent basic science plus equations along with sample problems and practice questions.


PET/CT Imaging

PET/CT Imaging

Author: Kanhaiyalal Agrawal

Publisher: Springer Nature

Published: 2021-12-02

Total Pages: 132

ISBN-13: 3030754766

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The aim of this book is to provide concise information and quick reference on the basics and practice of PET/CT for beginners. The chapters are written by Nuclear Medicine experts from different countries with enormous experience in PET/CT practice. Starting with the basics of PET/CT describing physics and the use of radiopharmaceuticals in PET/CT, the book explores the principle of PET/CT in radiotherapy planning. The last five chapters explore normal variation, pitfalls and artefacts commonly seen with various routinely used PET radiotracers. The text is enriched by tables and highlighted clinical cases for better understanding. This book will be of interest mostly to nuclear medicine physicians and radiologists, but it may be appealing also to a wider medical community including oncologists and radiotherapists.


Fundamentals of Oncologic PET/CT E-Book

Fundamentals of Oncologic PET/CT E-Book

Author: Gary A. Ulaner

Publisher: Elsevier Health Sciences

Published: 2018-06-21

Total Pages: 352

ISBN-13: 032356867X

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In the fast-changing age of precision medicine, PET/CT is increasingly important for accurate cancer staging and evaluation of treatment response. Fundamentals of Oncologic PET/CT, by Dr. Gary A. Ulaner, offers an organized, systematic introduction to reading and interpreting PET/CT studies, ideal for radiology and nuclear medicine residents, practicing radiologists, medical oncologists, and radiation oncologists. Synthesizing eight years’ worth of cases and lectures from one of the largest cancer centers in the world, this title provides a real-world, practical approach, taking you through the body organ by organ as it explains how to integrate both the FDG PET and CT findings to best interpret each lesion.


Molecular Imaging

Molecular Imaging

Author: Shankar Vallabhajosula

Publisher: Springer Science & Business Media

Published: 2009-07-13

Total Pages: 379

ISBN-13: 3540767355

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Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.


PET/CT Atlas on Quality Control and Image Artefacts

PET/CT Atlas on Quality Control and Image Artefacts

Author: International Atomic Energy Agency

Publisher:

Published: 2014

Total Pages: 99

ISBN-13: 9789201010148

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Positron emission tomography/computed tomography (PET/CT), as any other imaging modality, is acceptable for routine clinical and research applications only if technical pitfalls can be avoided. Artefacts from incorrect or sub-optimal acquisition procedures should be recognized and, if possible, corrected retrospectively and the resulting image information interpreted correctly, which entails an appreciation of variants of the represented image information. This publication provides guidance on the physics and technical aspects behind PET and PET/CT image distortions. Cases are presented to provide nuclear medicine and radiology professionals with an assortment of examples of possible image distortions and errors in order to support a correct image interpretation. Nearly 70 typical PET and PET/CT cases, comprising image sets and cases, have been collected in this volume, all catalogued and augmented with explanations as to the causes of, and solutions to, each individual image problem. The atlas will prove useful to physicists, physicians, technologists, and service engineers in the clinical field.


Grainger & Allison's Diagnostic Radiology

Grainger & Allison's Diagnostic Radiology

Author: Andy Adam

Publisher: Churchill Livingstone

Published: 2007

Total Pages: 0

ISBN-13: 9780443101632

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Organised along an organ and systems basis, this comprehensive reference source covers all diagnostic and interventional imaging techniques and modalities in an integrated, correlative fashion.


Clinical PET and PET/CT

Clinical PET and PET/CT

Author: H. Jadvar

Publisher: Springer Science & Business Media

Published: 2006-01-20

Total Pages: 277

ISBN-13: 1846281008

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A practical manual covering the full spectrum of PET and PET/CT imaging, now in common clinical practice, this book includes images of normal variants, artifacts, and pathologic conditions. Indications for and the relative clinical value of PET in the armamentarium of diagnostic medical imaging are reviewed. The information in the book is organized to be brief, concise, easy-to-understand and readily accessed. This book is intended for all health practitioners who need a concise reference and review of PET imaging indications, protocols and clinical applications. It will be useful to radiologists, nuclear medicine physicians, and clinicians who refer their patients to PET Centers for diagnostic imaging, including neurologists, neurosurgeons, psychiatrists, cardiologists, internists, and oncologists. Radiologic and nuclear medicine technologists, and physicians in training will also benefit from this work.


Positron Emission Tomography

Positron Emission Tomography

Author: Dale L. Bailey

Publisher: Springer Science & Business Media

Published: 2006-07-06

Total Pages: 381

ISBN-13: 1846280079

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Essential for students, science and medical graduates who want to understand the basic science of Positron Emission Tomography (PET), this book describes the physics, chemistry, technology and overview of the clinical uses behind the science of PET and the imaging techniques it uses. In recent years, PET has moved from high-end research imaging tool used by the highly specialized to an essential component of clinical evaluation in the clinic, especially in cancer management. Previously being the realm of scientists, this book explains PET instrumentation, radiochemistry, PET data acquisition and image formation, integration of structural and functional images, radiation dosimetry and protection, and applications in dedicated areas such as drug development, oncology, and gene expression imaging. The technologist, the science, engineering or chemistry graduate seeking further detailed information about PET, or the medical advanced trainee wishing to gain insight into the basic science of PET will find this book invaluable. This book is primarily repackaged content from the Basic Science section of the 'big' Valk book on PET. It contains new, completely revised and unchanged chapters covering the "basic sciences" section of the main book - total 18 chapters: 2 new (chapters 1, 16) 8 completely revised (chapters 4, 5, 8, 13, 14, 15, 17, 18) 3 minor corrections (chapters 2, 6, 11) 5 unchanged (chapters 3, 7, 9, 10, 12)


Mathematics and Physics of Emerging Biomedical Imaging

Mathematics and Physics of Emerging Biomedical Imaging

Author: Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging

Publisher: National Academies Press

Published: 1996-03-13

Total Pages: 261

ISBN-13: 0309552923

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This cross-disciplinary book documents the key research challenges in the mathematical sciences and physics that could enable the economical development of novel biomedical imaging devices. It is hoped that the infusion of new insights from mathematical scientists and physicists will accelerate progress in imaging. Incorporating input from dozens of biomedical researchers who described what they perceived as key open problems of imaging that are amenable to attack by mathematical scientists and physicists, this book introduces the frontiers of biomedical imaging, especially the imaging of dynamic physiological functions, to the educated nonspecialist. Ten imaging modalities are covered, from the well-established (e.g., CAT scanning, MRI) to the more speculative (e.g., electrical and magnetic source imaging). For each modality, mathematics and physics research challenges are identified and a short list of suggested reading offered. Two additional chapters offer visions of the next generation of surgical and interventional techniques and of image processing. A final chapter provides an overview of mathematical issues that cut across the various modalities.