Our understanding of the etiopathology of periodontal disease has changed greatly over the last decade. The huge diversity of species within the microbial biofilm and the enormous multi-layered complexity of the innate, inflammatory and adaptive immune responses generated in response to it warrant study and discussion. Comprising reviews from renowned experts in the field, this book presents a comprehensible overview of this exciting and pertinent subject matter. It provides new insights into the structure and composition of subgingival biofilms and the nature of the extracellular matrix. Further, a summary of current understanding of subgingival microbial diversity and an overview of experimental models used to dissect the functional characteristics of subgingival communities are presented. Other articles discuss the innate cellular and neutrophil responses to the periodontal biofilm. The role of antimicrobial peptides in the host response to biofilm bacteria and modern approaches to nonsurgical biofilm management are also discussed. Finally, this volume addresses advances in antibiotic use and proposes a paradigm shift in the pharmacological approach to periodontal disease management.
Periodontal disease (PD), an inflammatory disease of tooth supporting tissues that leads to progressive loss of periodontal ligament and bone, with pocket formation and / or recession of the gums, is widespread among the world adult population and a serious public health issue. In this book, Chapter One reviews the literature about the use of probiotics in periodontal disease, including in vitro, in vivo and clinical studies, in order to improve the understanding of probiotics role in periodontal disease and discusses the effectiveness of their use as a therapy for periodontitis. Chapter Two studies the model of periodontitis induction by ligature and presents a protocol for performing it in rats and mice, based on the experience of the authors research group, to guide researchers who wish to develop the model. Chapter Three focuses on nutritional and systemic risk factors for periodontitis, focusing on modifiable common risk factors that also impact cardiometabolic disease, which can be targeted through oral and medical health professionals for improving periodontal and cardiometabolic health. Chapter Four discusses the main manifestations of gingivitis, chronic periodontitis, aggressive periodontitis, and periodontal disease resulting from systemic diseases. In addition, the authors discuss the treatment options, highlighting the conventional periodontal therapy, systemic administration of antibiotics, and surgical treatments.
Polymicrobial diseases, those involving more than one etiologic agent, are more common than is generally realized and include respiratory diseases, gastroenteritis, conjunctivitis, keratitis, hepatitis, periodontal diseases, multiple sclerosis, genital infections, intra -- abdominal infections, and pertussis.
Periodontal disease is a chronic bacterial infection characterised by persistent inflammation, connective tissue breakdown and alveolar bone destruction. The chronic inflammation associated with periodontal disease represents the host response to bacterial plaque, mediated by the environment in which the response occurs. This book presents topical research data in the study of periodontal disease, including aesthetic periodontal therapy and root coverage techniques; clinical features of periodontal diseases in children and adolescents; biomechanics and the perioprosthetic patient; maternal periodontitis and perinatal outcomes; identifying patients with enhanced disease susceptibility in periodontal disease; and inflammatory mediators and oxidative stress in periodontal disease.
This book aims to bridge the gulf between the complex pathobiology of periodontal diseases and their assessment and diagnosis in dental practice. It provides a visual tour of the periodontium, how the host responds to periodontal pathogens, and re-classifies the diseases. Risk-factor identification is introduced prior to a step-by-step guide to diagnosis, commencing with the patient's first visit.
"Periodontal diseases" is a web-based resource intended to reach the contemporary practitioners as well as educators and students in the field of periodontology. It is fully searchable and designed to enhance the learning experience. Within the book a description is presented of the current concepts presenting the complex interactions of microbial fingerprint, multiple genotypes, and host modulations. In addition, an overview is given of the clinical outcome of the disease's progression, as influenced by the epigenetic factors. Emerging concepts on periodontitis as a risk factor for various systemic diseases and as a bilateral modulating factor have been elucidated in detail as well.
Free yourself from the downward spiral of scaling, root planing, gum grafts, flap surgery, chemicals, and the inevitable extractions and implants and cure gum disease (periodontitis) naturally. Ramiel Nagel's bestselling guide, Cure Tooth Decay, has inspired tens of thousands of readers to discover hidden and effective means to reduce dental cavities by at least 90 percent. In Cure Gum Disease Naturally, Nagel expands upon his original work and shows you the forgotten and suppressed cure for gum disease. The CDC now reports that about half of all adult Americans suffer from periodontal disease, with 8.5 percent of all adults having severe gum disease. And even worse, 23 percent of all adults aged sixty-five and older have lost all of their teeth. Despite the prevalence of periodontal disease, dentistry has not found the "cure" as it continues to allow adults to lose their teeth only to primarily offer the expensive and often painful alternative of dental implants. This is not a book that advocates for gum surgery, or for other chemical or harsh overpriced treatments with dubious results. This is a truly natural, holistic approach that primarily focuses on how you can use the food that you eat as medicine for your body, to give it specific and targeted nutrition, and to make your sad gums happy again. It will show you how to turn the frequent dreadful dental visits into a delight, and to help you stop worrying about the health of your teeth and gums so you can start living life-as you deserve to-once again. Take a bite out of life, improve how you feel, reduce your level of stress, and finally, at last, read a book that was truly written with a goal that you can align with, to get you out of the endless and unnecessary cycle of gum disease treatments that do not provide results that last because they never address the root cause. Cure Gum Disease Naturally is about you and your health. It begins with the story of how conventional dentistry no longer advocates and prescribes treatments based upon the agreed upon and proven cause of gum disease. You will learn how enlightened dentists Melvin Page and Harold Hawkins applied the research of esteemed dentist Weston Price in their practices to prevent the tragic loss of teeth by restoring gum health in their patients. You will then be led, step by step, through the evidence and the information that gives you a precise and detailed road map, using whole foods, to stop gum disease and to rebuild and repair your gums. Finally, you will be given essential information to navigate the dangerous waters of gum treatments, and find new ways to care for your teeth and gums that until now, few knew were even possible. Read Cure Gum Disease Naturally and learn how loose teeth can be firmed up and become rooted like a strong tree once again into your jaw bone, inflamed gums can become healthy, and bleeding can be greatly reduced and stopped. You will at last see clearly why you have succumbed to gum disease and know specific steps to take, by eating certain foods, to keep your gums healthy and thus keep your teeth for the rest of your life.
This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarkers in periodontal diagnosis is then presented in the light of the published data. The biological samples in which potential biomarkers are sought are evaluated comparatively, drawing attention to their strengths and weaknesses, and the available technologies for biomarker studies are reviewed. The potential benefits of biomarkers are also discussed with regard to the possible bidirectional interactions between periodontal diseases and systemic health. Finally, the past, present, and future of periodontics are examined from a broader perspective. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.
