Smoldering Ashes
Smoldering Ashes

Author: Charles F. Walker

Publisher: Duke University Press

Published: 1999-04-05

Total Pages: 350

ISBN-13: 0822382164

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In Smoldering Ashes Charles F. Walker interprets the end of Spanish domination in Peru and that country’s shaky transition to an autonomous republican state. Placing the indigenous population at the center of his analysis, Walker shows how the Indian peasants played a crucial and previously unacknowledged role in the battle against colonialism and in the political clashes of the early republican period. With its focus on Cuzco, the former capital of the Inca Empire, Smoldering Ashes highlights the promises and frustrations of a critical period whose long shadow remains cast on modern Peru. Peru’s Indian majority and non-Indian elite were both opposed to Spanish rule, and both groups participated in uprisings during the late colonial period. But, at the same time, seething tensions between the two groups were evident, and non-Indians feared a mass uprising. As Walker shows, this internal conflict shaped the many struggles to come, including the Tupac Amaru uprising and other Indian-based rebellions, the long War of Independence, the caudillo civil wars, and the Peru-Bolivian Confederation. Smoldering Ashes not only reinterprets these conflicts but also examines the debates that took place—in the courts, in the press, in taverns, and even during public festivities—over the place of Indians in the republic. In clear and elegant prose, Walker explores why the fate of the indigenous population, despite its participation in decades of anticolonial battles, was little improved by republican rule, as Indians were denied citizenship in the new nation—an unhappy legacy with which Peru still grapples. Informed by the notion of political culture and grounded in Walker’s archival research and knowledge of Peruvian and Latin American history, Smoldering Ashes will be essential reading for experts in Andean history, as well as scholars and students in the fields of nationalism, peasant and Native American studies, colonialism and postcolonialism, and state formation.

Assessing the Effects of the Gulf of Mexico Oil Spill on Human Health
Assessing the Effects of the Gulf of Mexico Oil Spill on Human Health

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2010-09-01

Total Pages: 201

ISBN-13: 0309161142

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From the origin of the leak, to the amount of oil released into the environment, to the spill's duration, the 2010 Gulf of Mexico oil spill poses unique challenges to human health. The risks associated with extensive, prolonged use of dispersants, with oil fumes, and with particulate matter from controlled burns are also uncertain. There have been concerns about the extent to which hazards, such as physical and chemical exposures and social and economic disruptions, will impact the overall health of people who live and work near the area of the oil spill. Although studies of previous oil spills provide some basis for identifying and mitigating the human health effects of these exposures, the existing data are insufficient to fully understand and predict the overall impact of hazards from the Deepwater Horizon oil spill on the health of workers, volunteers, residents, visitors, and special populations. Assessing the Effects of the Gulf of Mexico Oil Spill on Human Health identifies populations at increased risks for adverse health effects and explores effective communication strategies to convey health information to these at-risk populations. The book also discusses the need for appropriate surveillance systems to monitor the spill's potential short- and long-term health effects on affected communities and individuals. Assessing the Effects of the Gulf of Mexico Oil Spill on Human Health is a useful resource that can help policy makers, public health officials, academics, community advocates, scientists, and members of the public collaborate to create a monitoring and surveillance system that results in "actionable" information and that identifies emerging health risks in specific populations.

The Tupac Amaru Rebellion
The Tupac Amaru Rebellion

Author: Charles F. Walker

Publisher: Harvard University Press

Published: 2014-04-08

Total Pages: 333

ISBN-13: 0674416384

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The largest rebellion in the history of Spain's American empire—a conflict greater in territory and costlier in lives than the contemporaneous American Revolution—began as a local revolt against colonial authorities in 1780. As an official collector of tribute for the imperial crown, José Gabriel Condorcanqui had seen firsthand what oppressive Spanish rule meant for Peru's Indian population. Adopting the Inca royal name Tupac Amaru, he set events in motion that would transform him into Latin America's most iconic revolutionary figure. Tupac Amaru's political aims were modest at first. He claimed to act on the Spanish king's behalf, expelling corrupt Spaniards and abolishing onerous taxes. But the rebellion became increasingly bloody as it spread throughout Peru and into parts of modern-day Bolivia, Chile, and Argentina. By late 1780, Tupac Amaru, his wife Micaela Bastidas, and their followers had defeated the Spanish in numerous battles and gained control over a vast territory. As the rebellion swept through Indian villages to gain recruits and overthrow the Spanish corregidors, rumors spread that the Incas had returned to reclaim their kingdom. Charles Walker immerses readers in the rebellion's guerrilla campaigns, propaganda war, and brutal acts of retribution. He highlights the importance of Bastidas—the key strategist—and reassesses the role of the Catholic Church in the uprising's demise. The Tupac Amaru Rebellion examines why a revolt that began as a multiclass alliance against European-born usurpers degenerated into a vicious caste war—and left a legacy that continues to influence South American politics today.

Quantitative Fish Dynamics
Quantitative Fish Dynamics

Author: Terrance J. Quinn

Publisher: Oxford University Press, USA

Published: 1999

Total Pages: 561

ISBN-13: 0195076311

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The fields of fish population dynamics and stock assessment have seen major advances in the 1980s and 1990s, creating the need for a new synthesis. This text attempts that synthesis by presenting a contemporary approach for quantitative fisheries science that incorporates modern statistical and mathematical techniques. It emphasizes the link between biology and theory by explaining the assumptions inherent in the quantitative methods and models. The book covers key topics that are often overlooked in other texts, such as optimal harvesting, migratory stocks, and complex age and size-structured models. Quantitative Fish Dynamics is an ideal textbook for graduate and undergraduate courses in fish population dynamics and stock assessment. It is an indispensable reference work for fisheries scientists and others interested in conservation biology, fish and wildlife management, population ecology, and statistical applications.

Micronucleus Assay
Micronucleus Assay

Author: Robert C. Cole

Publisher:

Published: 2020

Total Pages: 0

ISBN-13: 9781536166781

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Micronucleus is defined as the small nucleus that forms whenever a chromosome or its fragment is not incorporated into one of the daughter nuclei during cell division. It is concluded that micronucleus assay can be used for risk prediction, screening, diagnosis and treatment of various chronic diseases. In this Micronucleus Assay: An Overview, the applications of micronucleus assay will be discussed. Ionisating radiations, ultraviolet rays, geogenic or anthropogenic pollutants can induce mutagenic, teratogenic or carcinogenic effects due to the induction of micro or macrolession over DNA. Several models have been used to measure the mutagenic and clastogenic effect of such agents. As such, the authors focus on one of these models: the micronucleus test. The micronucleus test can assess abnormalities earlier in the drug discovery pipeline, making structure/genotoxicity connection a possible system for drug characterization. Additionally, the authors provide knowledge about micronucleus assay and its usage in occupational toxicology studies. It is now recognized as one of the most successful and reliable assays for genotoxic carcinogens. The authors go on to present an overview of the evaluation of micronucleus assay by flow cytometry, reviewing the studies published in the international literature so far that employ different experimental designs for a variety of purposes. Humans can become exposed to a variety of chemical substances that can have adverse biological effects, and the sub-lethal genotoxicity can have the most far reaching and severe consequences like cancer or abnormal progeny as per the cell type involved. Hence, the penultimate chapter focuses on the significance of identifying and predicting potential genotoxic agents by using laboratory markers, thus regulating and preventing exposure to cancer causing agents In the concluding review, generation of micronucleus assay in the bone marrow cells of mice induced by various clastogenic chemicals, drugs, and radiation are elaborately elucidated. Bone marrow cells are easily susceptible to oxidative damage and sensitive to various clastogenic as well as aneugenic agents.

Neurotoxicity of Nanomaterials and Nanomedicine
Neurotoxicity of Nanomaterials and Nanomedicine

Author: Xinguo Jiang

Publisher: Academic Press

Published: 2016-10-03

Total Pages: 368

ISBN-13: 0128046201

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Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials. - Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology - Includes the most common nanoparticles, their applications, and mechanisms - Provides one of the first books to focus on nanomedicine and neurotoxicity

Genotoxicity
Genotoxicity

Author: Andor Kocsis

Publisher: Nova Science Publishers

Published: 2009

Total Pages: 0

ISBN-13: 9781607417149

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This book looks at genotoxicity which is a deleterious action on cell genetic material affecting its integrity. Genotoxic substances are known to be potentially mutagenic or carcinogenic, specifically those capable of causing genetic mutation and of contributing to the development of tumours. In humans, DNA damage or genotoxicity may be caused by exposure to outside agents like radiation, pesticides, combustion of hydrocarbon products as well as antineoplastic drugs. DNA damage could also come from inside of the body, determined mainly by excessive free radical production generated by some disease process. The importance then, is to identify the genotoxity and try to protect the body, which may be as simple as removing the source of exposure or providing protection against such agents. This new important book gathers the latest research from around the globe in this dynamic field of study.