Peptide And Protein Engineering For Biotechnological And Therapeutic Applications
Peptide And Protein Engineering For Biotechnological And Therapeutic Applications

Author: Pierre Rousselot-pailley

Publisher: World Scientific

Published: 2023-01-06

Total Pages: 520

ISBN-13: 9811261679

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Peptides and proteins are crucial biomolecules in life. The manifold functions they carry out range from molecular recognition and signaling to catalysis and immune response. However, the native systems are limited to a reduced toolbox of chemical functionalities as well as tridimensional structures. Widening these toolboxes could pave the way to engineer peptides and proteins with enhanced properties compared to their native counterparts and/or with structures and functions unprecedented in Nature. Advances in the chemical and biological synthesis of peptides and proteins, in computational tools, in molecular biology and in high-throughput screening methods are making this realm possible.This book aims to give an overview of the last developments in the field of peptide and protein engineering. It comprises a collection of chapters that span from the production of simple non-proteinogenic building blocks and peptidic scaffolds of different sizes and structures to more complex systems including peptide-based nanomaterials, enzymes and artificial metalloenzymes. Different strategies are described where chemical and biological tools have been developed and combined to attain the desired properties and sought functionalities.The diverse systems described in this book highlight the progress in this important field and represent the starting points for the development of functional biomolecules, biomaterials and hybrid systems capable of addressing key societal challenges of our times in relevant areas such health, environment and energy.

Peptide Applications in Biomedicine, Biotechnology and Bioengineering
Peptide Applications in Biomedicine, Biotechnology and Bioengineering

Author: Sotirios Koutsopoulos

Publisher: Woodhead Publishing

Published: 2017-11-16

Total Pages: 655

ISBN-13: 0081007426

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Peptide Applications in Biomedicine, Biotechnology and Bioengineering summarizes the current knowledge on peptide applications in biomedicine, biotechnology and bioengineering. After a general introduction to peptides, the book addresses the many applications of peptides in biomedicine and medical technology. Next, the text focuses on peptide applications in biotechnology and bioengineering and reviews of peptide applications in nanotechnology. This book is a valuable resource for biomaterial scientists, polymer scientists, bioengineers, mechanical engineers, synthetic chemists, medical doctors and biologists. - Presents a self-contained work for the field of biomedical peptides - Summarizes the current knowledge on peptides in biomedicine, biotechnology and bioengineering - Covers current and potential applications of biomedical peptides

Peptide and Protein Engineering
Peptide and Protein Engineering

Author: Olga Iranzo

Publisher: Humana

Published: 2021-07-23

Total Pages: 289

ISBN-13: 9781071607220

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This thorough book aims to present the methods that have enabled the success of peptides and proteins in a wide variety of applications. It opens with a section on chemical tools applied to the production or engineering of peptides and proteins, and concludes with a collection of chapters on biological approaches used to engineer structure and function in peptides and proteins. As a book in the Springer Protocols Handbooks series, chapters include the kind of detailed descriptions and tips necessary for successful results in practice. Authoritative and practical, Peptide and Protein Engineering: From Concepts to Biotechnological Applications will be of great use to scientists in academia and industry seeking a better understanding of the emerging principles and methodologies in peptide and protein engineering.

Enzyme Technology
Enzyme Technology

Author: Ashok Pandey

Publisher: Springer Science & Business Media

Published: 2006-04-28

Total Pages: 774

ISBN-13: 9780387292946

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Novel Biological and Biotechnological Applications in Plant Nematode Management
Novel Biological and Biotechnological Applications in Plant Nematode Management

Author: Mujeebur Rahman Khan

Publisher: Springer Nature

Published: 2023-12-10

Total Pages: 543

ISBN-13: 9819928931

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The volume focuses on novel and effective biological and biotechnological methods for managing major plant parasitic nematodes in economically important agricultural crops. Nematodes develop a wide variety of interactions with soil microbes and host plants, and cause enormous losses in crop yields equivalent to around USD 173 billion annually. In view of growing concern for pesticide contamination in crops, coupled with ban on several efficacious pesticides, and increasing demand for organic foods, the biological and biotechnological approaches offer a good alternative to chemicals for managing nematode infestations in agricultural crops. The book embodies twenty-two chapters which are arranged in two groups. The first group covers different novel methods of nematode management such as biotechnological, biopesticides, microbial consortia, host resistance, omics technology, transgenics, nano-nematicides, nano-diagnosis, etc. The second groups of chapters describe important nematode problems in major crops such as cereals, vegetables, pulses, spices, wood yielding conifers, etc. Overall, the book collates the latest information on above topics and offers practical solutions to the limitations and challenges in the existing management technologies. This book is of interest and serves up-to-date and elaborated information to agriculture researchers, teachers, scientists, under-graduates, post-graduates, plant nematologists, plant pathologists, plant protectionists, agronomists, horticulturalists, helminthologists, extension workers, and NGOs.

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair
Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Author: Mario Barbosa

Publisher: Woodhead Publishing

Published: 2017-09-25

Total Pages: 392

ISBN-13: 008100852X

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Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. - Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration - Explores protein and peptides from the fundamentals, to processing and applications - Written by an international group of leading biomaterials researchers

Non-Natural Amino Acids
Non-Natural Amino Acids

Author:

Publisher: Academic Press

Published: 2009-07-24

Total Pages: 334

ISBN-13: 0080921639

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By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes published, each Methods in Enzymology volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. - Demonstrates how the tools and principles of chemistry combined with the molecules and processes of living cells can be combined to create molecules with new properties and functions found neither in nature nor in the test tube - Presents new insights into the molecular mechanisms of complex biological and chemical systems that can be gained by studying the structure and function of non-natural molecules - Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

Microbial Production of Food Ingredients, Enzymes and Nutraceuticals
Microbial Production of Food Ingredients, Enzymes and Nutraceuticals

Author: Brian McNeil

Publisher: Elsevier

Published: 2013-03-21

Total Pages: 641

ISBN-13: 0857093541

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Bacteria, yeast, fungi and microalgae can act as producers (or catalysts for the production) of food ingredients, enzymes and nutraceuticals. With the current trend towards the use of natural ingredients in foods, there is renewed interest in microbial flavours and colours, food bioprocessing using enzymes and food biopreservation using bacteriocins. Microbial production of substances such as organic acids and hydrocolloids also remains an important and fast-changing area of research. Microbial production of food ingredients, enzymes and nutraceuticals provides a comprehensive overview of microbial production of food ingredients, enzymes and nutraceuticals.Part one reviews developments in the metabolic engineering of industrial microorganisms and advances in fermentation technology in the production of fungi, yeasts, enzymes and nutraceuticals. Part two discusses the production and application in food processing of substances such as carotenoids, flavonoids and terponoids, enzymes, probiotics and prebiotics, bacteriocins, microbial polysaccharides, polyols and polyunsaturated fatty acids.Microbial production of food ingredients, enzymes and nutraceuticals is an invaluable guide for professionals in the fermentation industry as well as researchers and practitioners in the areas of biotechnology, microbiology, chemical engineering and food processing. - Provides a comprehensive overview of microbial flavours and colours, food bioprocessing using enzymes and food biopreservation using bacteriocins - Begins with a review of key areas of systems biology and metabolic engineering, including methods and developments for filamentous fungi - Analyses the use of microorganisms for the production of natural molecules for use in foods, including microbial production of food flavours and carotenoids

Plant Cyclotides
Plant Cyclotides

Author:

Publisher: Academic Press

Published: 2015-11-24

Total Pages: 404

ISBN-13: 0128007974

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Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. Currently in its 76th volume, the series features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. - Publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences - Contains commentary by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology - This volume features reviews of the fast moving field of plant cyclotides

Pharmaceutical Biotechnology
Pharmaceutical Biotechnology

Author: Gary Walsh

Publisher: John Wiley & Sons

Published: 2013-04-25

Total Pages: 499

ISBN-13: 111868575X

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Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed