Hundreds of neonates and children are at risk for thrombotic complications related to interventions in cardiac and renal disease, treatments for leukemia and lupus, and ischemic stroke. The authors lay a foundation in the principles of hemostasis, congenital prethrombotic disorders, and the epidemiology of venous and arterial thromboembolism. The management protocols embrace heparin, oral anticoagulants, and thrombolytic therapy.
Andrew’s Handbook of Pediatric Thromboembolism and Stroke, Third Editionis created as a manual in pocketbook format. This new edition presents guidelines for initiating and monitoring existing and new drug therapies for the treatment of thromboembolic complications in children.
In Canada alone there are hundreds of neonates and children at risk for thrombotic complications related to interventions in cardiac and renal disease, treatments for leukemia and lupus, and ischemic stroke. The authors lay a foundation in the principles of hemostasis, congenital prethrombotic disorders, and the epidemiology of venous and arterial thromboembolism. The management protocols embrace heparin, oral anticoagulants, and thrombolytic therapy.
The new third edition of Pediatric Stroke and Cerebrovascular Disorders provides a modern clinical approach to managing stroke and other cerebrovascular problems in infants, children, and adolescents. Incorporating data from important clinical trials and case series, recommendations from the American Heart Association evidence-based paper on the management of pediatric stroke, and the latest information on new diagnostic techniques, the book offers a comprehensive analysis of the current thinking and practice by three physicians who have vast clinical experience in this challenging field. The third edition of this classic work has been completely updated and rewritten to reflect current science and practice. Covering occurrence, etiology, diagnosis, and treatment, this integrated state-of-the-art text is essential reading for anyone involved in the care of children with suspected stroke or other cerebrovascular abnormalities. The third edition of this classic work has been completely updated and rewritten to reflect current science and practice. An extensive, entirely new chapter on treatment provides specific guidance on when to use antiplatelet agents, anticoagulants, and thrombolytic agents in children and also includes a section on neurorehabilitation after stroke. An expanded and thoroughly updated diagnostic approach chapter covers the latest applications in stroke imaging such as computed tomography angiography, diffusion weighted MRI, and perfusion CT. The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. Features of Pediatric Stroke and Cerebrovascular Disorders, Third Edition Include: Comprehensive in scope: detailed analysis of the pathogenesis, diagnosis, and treatment of cerebrovascular disorders in children with many evidence-based management guidelines The third edition has been updated to include recommendations from the AHA consensus guidelines All chapters in the third edition have been revised and updated An extensive, entirely new chapter on treatment provides specific guidance on when to use antiplatelet agents, anticoagulants, and thrombolytic agents in children Stresses the etiology and pathophysiology of childhood stroke as the basis for evaluation and treatment Maintains the practical, clinical flavor established in previous editions, with numerous illustrations and useful suggestions for patient care Written by internationally known stroke experts: Dr. Roach chaired the AHA panel that produced the consensus guidelines on childhood stroke and Drs. Lo and Heyer have published extensively on stroke and related topics
Several hundred thousand episodes of thromboemblic incidents are experienced in children every year. World recognized expert, Dr. Monagle, has studied thousands of cases and based on his research, he provides the reader with guidelines for the proper diagnosis and therapies. Andrew's Pediatric Thromboembolism and Stroke, Fourth Edition, presents guidelines for initiating and monitoring existing and new drug therapies for the treatment of thromboembolic complications in children.
Venous thromboembolism (VTE) occurs less often in children than adults and therefore remains underrecognized despite increasing in incidence. Due to the risk of mortality, short- and long-term morbidity, and increased healthcare costs associated with pediatric VTE, this entity merits better understanding and consideration. With this Research Topic, we aim to highlight some special considerations of pediatric VTE, namely risk factors and epidemiology, rare types of pediatric thrombosis and considerations unique to specific clinical patient subgroups, approaches to management and treatment, and prevention
This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
Stroke occuring in childhood although less common, presents serious challenges. This guideline is based on the expertise of a multidisciplinary working group and include the views of patients, parents and families.
Background and AimsTreatment of children with acute ischemic stroke with tissue plasminogen activator (tPA) or endovascular thrombectomy requires timely diagnosis. Widespread diagnostic delay prompted pediatric centers in the United States to develop multidisciplinary teams to respond emergently to children with acute-onset focal neurologic deficits. We describe here a decrease in the time to diagnosis of children presenting to the emergency department (ED) with acute-onset focal neurologic deficits after the establishment of a pediatric stroke alert system.MethodClinical and demographic information were reviewed for children who presented to the Boston Children's Hospital ED with acute-onset focal neurologic deficits for 2.5 years before and after the implementation of a stroke alert system.ResultsSixty-eight children presented with acute-onset focal neurologic deficits after implementation of a stroke alert system. Thirteen children presented with such symptoms before establishment of a stroke alert system. Time from ED arrival to the start of neuroimaging decreased significantly after implementation of a stroke alert system (median 196 v. 82 minutes before and after stroke alert system implementation, respectively; p
A succinct summary of the key principles and facts that guide the everyday practice of modern, clinical paediatric hematology. Covering all the information necessary for examinations in the topic, this book is ideal for postgraduates studying paediatric hematology, as well as for junior doctors in training.
