Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Pathology, Toxicogenetics, and Criminalistics of Drug Abuse presents a detailed introduction to the cutting-edge advances in this emerging field. Beginning with a definition and explanation of the schedu
Beginning with a definition and explanation of scheduling of controlled substances, Pathology, Toxicogenetics, and Criminalistics of Drug Abuse covers investigative methods for all illegal drugs and several legitimate pharmaceuticals that are used illicitly, including steroids. It covers the latest techniques used to analyze drugs in the forensic laboratory including physical characteristics and chemical confirmatory tests. It discusses new theories and findings in toxicogenetics, details pathologic changes in the body due to drug use, and examines specific effects on the heart, lung, and central nervous system. More that 70 tables and figures illustrate and complement the text and the information is supported by extensive references
Medical examiners play an increasingly important role in society as unexpected and violent deaths increase, not only due to crime, but also due to new toxins in the environment, emerging diseases crossing from animals to humans, bizarre suicides, sadistic sexual practices, and other non-natural causes. John Miletich and Tia Lindstrom take us into the world of these medical detectives. Biological clues from bite marks and skin abnormalities to blood chemical levels and brain oxygenation are just some factors exposed in their quest for truth and justice. We learn the basics of death determination from rigor and livor mortis to signs of death by design, drug use, disease, suicide, and more. We also come to understand the tools of this work, from the Stryker's Saw to the grocer's scale, and tests that reveal factors from DNA evidence to toxins from insect bites. Each case begins with a biological mystery and ends with a conclusion that can provide loved ones with relief, or shock. Miletich, who trained at the Alberta Office of the Chief Medical Examiner and with the Royal Canadian Mounted Police, teams with Lindstrom to introduce readers to the medical examiner's role, including autopsy techniques and analysis. Twists and turns emerge as what was initially thought to be a murder proves to be suicide; what was suspected to be a natural death proves to be murder or environmental poisoning; or what was thought to be an accidental death proves to be something more sinister. This work includes appendices with guides to Medical Examiner organizations, seminars, and conventions.
Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the
Written for practitioners in the field, this critically acclaimed bestseller provides authoritative information focused on the investigation of drug-related deaths and practical approaches to the detection of drug abuse. Organized to provide forensic investigators and pathologists with ready access to the authoritative and comprehensive information
A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. - Chapters written by world-renowned contributors who are experts in their fields - Includes the latest research in preclinical drug testing and international guidelines - Covers preclinical toxicology in small molecules and biologics in one single source
Forensic Medicine encompasses all areas in which medicine and law interact. This book covers diverse aspects of forensic medicine including forensic pathology, traumatology and violent death, sudden and unexpected death, clinical forensic medicine, toxicology, traffic medicine, identification, haemogenetics and medical law. A knowledge of all these subdisciplines is necessary in order to solve routine as well as more unusual cases. Taking a comprehensive approach the book m.oves beyond a focus on forensic pathology to include clinical forensic medicine and forensic toxicology. All aspects of forensic medicine are covered to meet the specialist needs of daily casework. Aspects of routine analysis and quality control are addressed in each chapter. The book provides coverage of the latest developments in forensic molecular biology, forensic toxicology, molecular pathology and immunohistochemistry. A must-have reference for every specialist in the field this book is set to become the bench-mark for the international forensic medical community.
This invaluable textbook, written by international experts, covers all the main elements of forensic toxicology and analytical toxicology techniques as well as the important parts of pharmacokinetics, drug metabolism, and pharmacology in general, with a particular focus on drugs of abuse.
A concise, robust introduction to the various topics covered by the discipline of forensic chemistry The Forensic Chemistry Handbook focuses on topics in each of the major chemistry-related areas of forensic science. With chapter authors that span the forensic chemistry field, this book exposes readers to the state of the art on subjects such as serology (including blood, semen, and saliva), DNA/molecular biology, explosives and ballistics, toxicology, pharmacology, instrumental analysis, arson investigation, and various other types of chemical residue analysis. In addition, the Forensic Chemistry Handbook: Covers forensic chemistry in a clear, concise, and authoritative way Brings together in one volume the key topics in forensics where chemistry plays an important role, such as blood analysis, drug analysis, urine analysis, and DNA analysis Explains how to use analytical instruments to analyze crime scene evidence Contains numerous charts, illustrations, graphs, and tables to give quick access to pertinent information Media focus on high-profile trials like those of Scott Peterson or Kobe Bryant have peaked a growing interest in the fascinating subject of forensic chemistry. For those readers who want to understand the mechanisms of reactions used in laboratories to piece together crime scenes—and to fully grasp the chemistry behind it—this book is a must-have.
