Oxidative Damage & Repair

Oxidative Damage & Repair

Author: Kelvin J. A. Davies

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 928

ISBN-13: 1483287661

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This book was inspired by the presentations delivered at the Oxidative Damage & Repair Symposium (November, 1990). The book is organized into 20 chapters which mirror the 20 session topics of the Oxidative Damage & Repair Symposium.


Advances in DNA Damage and Repair

Advances in DNA Damage and Repair

Author: Miral Dizdaroglu

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 502

ISBN-13: 1461548659

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In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This volume covers the most recent developments in this research field and contains contributions from scientists working in various fields.


Oxidative Damage to Nucleic Acids

Oxidative Damage to Nucleic Acids

Author: Mark D. Evans

Publisher: Springer Science & Business Media

Published: 2009-06-11

Total Pages: 228

ISBN-13: 0387729747

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This book provides up-to-date coverage of selected topics in nucleic acid oxidation. The topics have been selected to cover everything from basic chemical mechanisms, repair of damage and the biological and pathological meaning of DNA oxidation. The chapters are authored by leading, research active, international experts in the respective topics.


RNA Damage and Repair

RNA Damage and Repair

Author: Ioly Kotta-Loizou

Publisher: Springer Nature

Published: 2021-07-04

Total Pages: 180

ISBN-13: 3030765717

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Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems). Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.


Critical Reviews of Oxidative Stress and Aging

Critical Reviews of Oxidative Stress and Aging

Author: Richard G. Cutler

Publisher: World Scientific

Published: 2003

Total Pages: 874

ISBN-13: 9789812389961

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This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.


DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies

DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies

Author: Marco E. M. Peluso

Publisher: MDPI

Published: 2021-09-01

Total Pages: 188

ISBN-13: 3036512705

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Computational fluid dynamics (CFD), which uses numerical analysis to predict and model complex flow behaviors and transport processes, has become a mainstream tool in engineering process research and development. Complex chemical processes often involve coupling between dynamics at vastly different length and time scales, as well as coupling of different physical models. The multiscale and multiphysics nature of those problems calls for delicate modeling approaches. This book showcases recent contributions in this field, from the development of modeling methodology to its application in supporting the design, development, and optimization of engineering processes.


Brain Aging

Brain Aging

Author: David R. Riddle

Publisher: CRC Press

Published: 2007-04-19

Total Pages: 408

ISBN-13: 9781420005523

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Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur