This publication focuses on the period of ontogenetic development of man, which takes place between fertilization up to birth - the period of prenatal development. It provides a summary of the most important knowledge from the field of embryology and explains in a comprehensible way the complicated processes of human development before birth. The book is accompanied by a large number of schematic illustrations.
Nearly 10 years have elapsed since I finished writing the first edition of Intro duction to Molecular Embryology. During this period, molecular embryology has made great strides forward, but without undergoing a major revolution; there fore, the general philosophy and outline of the book have remained almost un changed. However, all the chapters had to be almost completely rewritten in or der to introduce new facts and to eliminate findings which have lost interest or have been disproved. There was a major gap in the first edition of this book: very little was said about mammalian eggs despite their obvious interest for mankind. Research on mammalian eggs and embryos is so active today that this important topic deserves a full chapter in a book concerned with molecular embryology. Therefore, I am very thankful to my colleague Dr. Henri Alexandre, who has written a chapter on mammalian embryology (Chap. 9) and has prepared all the illustrations for this book.
Outlining the most important concepts of clinical embryology, the second edition of this full color atlas gives a well-illustrated overview of human development before birth. Each chapter has been thoroughly revised with the most up-to-date information. Accompanied by authoritative descriptions, this superb resource provides a step-by-step review of normal and abnormal embryonic and fetal development through hundreds of color photographs, 3-dimensional drawings, electron micrographs, sonograms, MR images, and pen-and-ink sketches. It also includes photographs and tables indicating periods when tissue and organ formations may be affected by teratogenic agents.
This concise yet comprehensive guide is focused on the curriculum and current exam style of the MRCOG Part 1 examination. It integrates clinical knowledge with basic science, providing readers with a deeper understanding of pathophysiology of medical disorders in obstetrics and gynaecology. The lead editor is a member of the Part 1 Examination Committee and her insights are skilfully woven into the book's revision notes, sample Single Best Answer (SBA) question and answer explanations, and tips on exam technique. The book encourages a structured thought process to develop, making it easier for clinicians to make differential diagnoses and conduct relevant investigations and treatment plans. The focus on basic sciences also endows readers with the ability to develop research ideas and evaluate findings. Featuring easy-to-read text, highlighted key points, illustrations, and plenty of practice papers, this succinct guide is essential preparation reading for trainee obstetricians and gynaecologists taking the challenging Part 1 MRCOG exam.
This is the most comprehensive book to be written on the subject of fetal MRI. It provides a practical hands-on approach to the use of state-of-the-art MRI techniques and the optimization of sequences. Fetal pathological conditions and methods of prenatal MRI diagnosis are discussed by organ system, and the available literature is reviewed. Interpretation of findings and potential artifacts are thoroughly considered with the aid of numerous high-quality illustrations. In addition, the implications of fetal MRI are explored from the medico-legal and ethical points of view. This book will serve as a detailed resource for radiologists, obstetricians, neonatologists, geneticists, and any practitioner wanting to gain an in-depth understanding of fetal MRI technology and applications. In addition, it will provide a reference source for technologists, researchers, students, and those who are implementing a fetal MRI service in their own facility.
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
A thorough appreciation of the cellular, molecular and tissue changes which precede the birth of an animal is a fundamental requirement for understanding normal structural development and also abnormal processes which result in congenital defects. This textbook provides information relevant to many subjects taught in preclinical, paraclinical and clinical years. Early chapters describe and explain sequential events relating to the division, growth and differentiation of cells and to the formation of foetal membranes, implantation and placentation. Succeeding chapters trace the origin, growth, development and maturation of the major body systems. Age determination of the embryo and foetus is reviewed in a single chapter. Genetic, chromosomal and environmental factors which adversely affect pre-natal development are reviewed in the final chapter. A reading list at the end of each chapter offers additional sources of information on the topics discussed. Tables, flow diagrams and numerous hand-drawn illustrations provide information in a form which complements the concepts presented in the text. Key features: Written by a team which includes members with expertise in developmental anatomy, molecular biology and clinical aspects of veterinary medicine. The authors have extensive experience in the teaching of veterinary embryology and cognate subjects. Illustrations, hand-drawn by a veterinary graduate, are used extensively to explain organogenesis and system development. An explanatory glossary provides concise information on specialised terms used in the text. The index is designed for easy retrieval of information.