A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level.
Organic Reaction Mechanisms 2009, the 45th annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2009. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation. This volume includes a 5-year cumulative index.
Organic chemistry is a core part of the chemistry curricula, andadvanced levels texts often obscure the essential frameworkunderlying and uniting the vast numbers of reactions as a result ofthe high level of detail presented. The material in this book iscondensed into a manageable text of 350 pages and presented in aclear and logical fashion, focusing purely on the basics of thesubject without going through exhaustive detail or repetitiveexamples. The book aims to bridge the gap between undergraduateorganic chemistry textbooks and advanced level textbooks, beginningwith a basic introductory course and arranging the reactionmechanisms according to an ascending order of difficulty. As such,the author believes the book will be excellent primer for advancedpostgraduates Reaction Mechanisms in Organic Synthesis is written fromthe point of view of the synthetic organic chemist, enablingstudents and researchers to understand and expand on reactionscovered in foundation courses, and to apply them in a practicalcontext by designing syntheses. As a further aid to the practicalresearch student, the content is organized according to theconditions under which a reaction is executed rather than by thetypes of mechanisms. Particular emphasis is placed on controllingstereospecificity and regiospecificity. Topics covered include: Transition metal mediated carbon-carbon bond formationreactions Use of stabilized carbanions, ylides and enamines forcarbon-carbon bond formation reactions, Advanced level use of oxidation and reduction reagents insynthesis. As a modern text, this book stands out from its competitors dueto its comprehensive coverage of recently published research. Thebook contains specific examples from the latest literature,covering modern reactions and the latest procedural modifications.The focus on contemporary and synthetically useful reactionsensures that the contents are specifically relevant and attractiveto postgraduate students and industrial organic chemists.
Find an easier way to learn organic chemistry with Arrow-Pushing in Organic Chemistry: An Easy Approach to Understanding Reaction Mechanisms, a book that uses the arrow-pushing strategy to reduce this notoriously challenging topic to the study of interactions between organic acids and bases. Understand the fundamental reaction mechanisms relevant to organic chemistry, beginning with Sn2 reactions and progressing to Sn1 reactions and other reaction types. The problem sets in this book, an excellent supplemental text, emphasize the important aspects of each chapter and will reinforce the key ideas without requiring memorization.
Strategies and Solutions to Advanced Organic Reaction Mechanisms: A New Perspective on McKillop's Problems builds upon Alexander (Sandy) McKillop’s popular text, Solutions to McKillop’s Advanced Problems in Organic Reaction Mechanisms, providing a unified methodological approach to dealing with problems of organic reaction mechanism. This unique book outlines the logic, experimental insight and problem-solving strategy approaches available when dealing with problems of organic reaction mechanism. These valuable methods emphasize a structured and widely applicable approach relevant for both students and experts in the field. By using the methods described, advanced students and researchers alike will be able to tackle problems in organic reaction mechanism, from the simple and straight forward to the advanced. Provides strategic methods for solving advanced mechanistic problems and applies those techniques to the 300 original problems in the first publication Replaces reliance on memorization with the understanding brought by pattern recognition to new problems Supplements worked examples with synthesis strategy, green metrics analysis and novel research, where available, to help advanced students and researchers in choosing their next research project
How To Solve Organic Reaction Mechanisms: A Stepwise Approach is an upgraded and much-expanded sequel to the bestselling text Reaction Mechanisms at a Glance. This book takes a unique approach to show that a general problem-solving strategy is applicable to many of the common reactions of organic chemistry, demonstrating that logical and stepwise reasoning, in combination with a good understanding of the fundamentals, is a powerful tool to apply to the solution of problems. Sub-divided by functional group, the book uses a check-list approach to problem-solving using mechanistic organic chemistry as its basis. Each mechanistic problem is presented as a two-page spread; the left-hand page introduces the problem and provides a stepwise procedure for working through the reaction mechanisms, with helpful hints about the underlying chemistry. The right-hand page contains the full worked solution and summary. This revised edition includes the following updates: A new chapter which applies the problem solving strategy to ligand coupling reactions using transition metals Much-expanded set of fully worked problems Over 40 further problems (with answers for tutors) for use in tutorials How To Solve Organic Reaction Mechanisms: A Stepwise Approach is an essential workbook for all students studying organic chemistry, and a useful aide for teachers of undergraduate organic chemistry to use in their tutorials.
Presentation is clear and instructive: students will learn to recognize that many of the reactions in organic chemistry are closely related and not independent facts needing unrelated memorization. The book emphasizes that derivation of a mechanism is not a theoretical procedure, but a means of applying knowledge of other similar reactions and reaction conditions to the new reaction. Brief summaries of required basic knowledge of organic structure, bonding, stereochemistry, resonance, tautomerism, and molecular orbital theory Definitions of essential terms Typing and classification of reactions Hints (rules) for deriving the most likely mechanism for any reaction
Organic Reaction Mechanisms 2016, the 52nd annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2016. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements
Organic chemistry is a core part of the chemistry curricula, and advanced levels texts often obscure the essential framework underlying and uniting the vast numbers of reactions as a result of the high level of detail presented. The material in this book is condensed into a manageable text of 350 pages and presented in a clear and logical fashion, focusing purely on the basics of the subject without going through exhaustive detail or repetitive examples. The book aims to bridge the gap between undergraduate organic chemistry textbooks and advanced level textbooks, beginning with a basic introductory course and arranging the reaction mechanisms according to an ascending order of difficulty. As such, the author believes the book will be excellent primer for advanced postgraduates Reaction Mechanisms in Organic Synthesis is written from the point of view of the synthetic organic chemist, enabling students and researchers to understand and expand on reactions covered in foundation courses, and to apply them in a practical context by designing syntheses. As a further aid to the practical research student, the content is organized according to the conditions under which a reaction is executed rather than by the types of mechanisms. Particular emphasis is placed on controlling stereospecificity and regiospecificity. Topics covered include: Transition metal mediated carbon-carbon bond formation reactions Use of stabilized carbanions, ylides and enamines for carbon-carbon bond formation reactions, Advanced level use of oxidation and reduction reagents in synthesis. As a modern text, this book stands out from its competitors due to its comprehensive coverage of recently published research. The book contains specific examples from the latest literature, covering modern reactions and the latest procedural modifications. The focus on contemporary and synthetically useful reactions ensures that the contents are specifically relevant and attractive to postgraduate students and industrial organic chemists.
