Organ Regeneration Based on Developmental Biology
Organ Regeneration Based on Developmental Biology

Author: Takashi Tsuji

Publisher: Springer

Published: 2017-03-30

Total Pages: 264

ISBN-13: 981103768X

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This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science.

Organ Regeneration
Organ Regeneration

Author: L. D. Liozner

Publisher: Springer

Published: 2012-06-15

Total Pages: 330

ISBN-13: 9781468484588

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The main theme of this monograph - conditions of regenera tion of organs in mammals - reflects an area of increasing empha sis which permeates much current Soviet research on regeneration. The introduction of this theme goes back about 25 years, and empha sis on the influence of environmental conditions upon regenerative processes has fluctuated until the mid-1960s, when the viewpoints on this subject were established in much the same form as they are expressed in this book. For years, Russian regeneration research has been charac terized by the presence of several dominant and often conflicting schools of thought. Since an acquaintance with these makes the in terpretation of many of the theoretical implications of this book, particularly in the introductory and concluding chapters, consider ably clearer, those not familiar with the Russian literature might profit by reading my brief survey of this field (Carlson, B. M., 1968. Re generation research in the Soviet Union, Anat. Rec., 160:665-674).

Organ Regeneration
Organ Regeneration

Author: L. D. Liozner

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 335

ISBN-13: 1468484567

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The main theme of this monograph - conditions of regenera tion of organs in mammals - reflects an area of increasing empha sis which permeates much current Soviet research on regeneration. The introduction of this theme goes back about 25 years, and empha sis on the influence of environmental conditions upon regenerative processes has fluctuated until the mid-1960s, when the viewpoints on this subject were established in much the same form as they are expressed in this book. For years, Russian regeneration research has been charac terized by the presence of several dominant and often conflicting schools of thought. Since an acquaintance with these makes the in terpretation of many of the theoretical implications of this book, particularly in the introductory and concluding chapters, consider ably clearer, those not familiar with the Russian literature might profit by reading my brief survey of this field (Carlson, B. M., 1968. Re generation research in the Soviet Union, Anat. Rec., 160:665-674).

Regenerative Engineering and Developmental Biology
Regenerative Engineering and Developmental Biology

Author: David M. Gardiner

Publisher: CRC Press

Published: 2017-08-21

Total Pages: 498

ISBN-13: 1351646494

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Regenerative Engineering and Developmental Biology: Principles and Applications examines cutting-edge developments in the field of regenerative engineering. Specific attention is given to activities that embrace the importance of integrating developmental biology and tissue engineering, and how this can move beyond repairing damage to body parts to instead regenerate tissues and organs. The text furthermore focusses on the five legs of the field of regenerative engineering, including: materials, developmental biology, stem cells, physics, and clinical translation. This book was written by leading developmental biologists; each chapter examines the processes that these biologists study and how they can be advanced by using the tools available in tissue engineering/biomaterials. Individual chapters are complete with concluding remarks and thoughts on the future of regenerative engineering. A list of references is also provided to aid the reader with further research. Ultimately, this book achieves two goals. The first encourages the biomedical community to think about how inducing regeneration is an engineering problem. The second goal highlights the discoveries with animal regeneration and how these processes can be engineered to regenerate body parts. Regenerative Engineering and Developmental Biology: Principles and Applications was written with undergraduate and graduate-level biomedical engineering students and biomedical professionals in mind.

Organ Regeneration
Organ Regeneration

Author: Takashi Tsuji

Publisher:

Published: 2017

Total Pages: 248

ISBN-13: 9781493969494

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This volume provides readers with a better understanding of organogenesis in developmental biology and next-generation organ regenerative therapy. This book focuses on recent studies of organ regeneration from stem cells using in vitro 3D cell culture and manipulation. The chapters cover topics such as generation of a 3D retinal tissue formation; functional salivary gland regeneration; liver regeneration using cultures liver bud; and in vivo model of small intestine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and thorough, Organ Regeneration: 3D Stem Cell Culture and Manipulation is a valuable resource for scientists and researchers who are interested in this field.

Developmental Biology and Musculoskeletal Tissue Engineering
Developmental Biology and Musculoskeletal Tissue Engineering

Author: Martin J. Stoddart

Publisher: Academic Press

Published: 2018-04-24

Total Pages: 272

ISBN-13: 0128115386

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Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair

Organ Development
Organ Development

Author:

Publisher: Academic Press

Published: 2019-02-21

Total Pages: 502

ISBN-13: 0128104902

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Organ Development, Volume 132, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapter written by an international board of authors. This volume highlights cogent reviews of the development, maintenance and regeneration/repair of several organ systems, from eye to kidney, to the musculoskeletal system. Many reviews highlight new techniques or technologies that are currently pushing the field. The role of both embryonic and adult stem cells are highlighted and senior authors are all women scientists. Provides the authority and expertise of leading contributors from an international board of author Presents the latest release in this series Updated release includes the latest information on organ development

Organ Regeneration
Organ Regeneration

Author: joydeep basu

Publisher: Humana Press

Published: 2013-03-14

Total Pages: 0

ISBN-13: 9781627033626

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Tissue engineering and regenerative medicine represents a wide array of cell, biomaterial and cell/biomaterial based approaches focusing on the repair, augmentation, and regeneration of diseases tissues and organs. Organ Regeneration: Methods and Protocols has been assembled in response to the growing interest in organ and tissue regeneration as a means to treat disease. Topics cover methods such as isolation and characterization of cells from selected soft tissues and solid organs, preparation and evaluation of natural and synthetic biomaterial scaffolding, implantation of regenerative constructs within experimental animals, and evaluation of regenerative outcomes by molecular and histological methodologies. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Organ Regeneration: Methods and Protocols serves as a detailed guide to aid newcomers and seasoned veterans in their developmental and experimental work in tissue engineering and regenerative medicine.

Stem Cells & Regenerative Medicine
Stem Cells & Regenerative Medicine

Author: Krishnarao Appasani

Publisher: Springer Science & Business Media

Published: 2010-11-01

Total Pages: 632

ISBN-13: 1607618605

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Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.