Optimization and Imaging Analysis of Carbohydrate Microarrays
Author: Kathryn McGregor Bolles
Publisher:
Published: 2011
Total Pages: 80
ISBN-13:
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Author: Kathryn McGregor Bolles
Publisher:
Published: 2011
Total Pages: 80
ISBN-13:
DOWNLOAD EBOOKAuthor: Jang B. Rampal
Publisher: Springer Science & Business Media
Published: 2008-02-03
Total Pages: 927
ISBN-13: 1597453048
DOWNLOAD EBOOKThis second part in the two-volume work Microarrays details applications and data analysis. It includes insight into non-mammalian vertebrate systems, processes and protocols for high quality glass-based microarrays. Coverage includes applications in DNA, peptide, antibody and carbohydrate microarraying, oligonucleotide microarrays generated from hydrolysis PCR probe sequences, microarray platforms in clinical practice, and screening of cDNA libraries on glass slide microarrays. Authors in this volume also discuss protocols for predicting DNA duplex stability on oligonucleotide arrays and integrated analysis of microarray results.
Author: Karl Fraser
Publisher: CRC Press
Published: 2010-01-25
Total Pages: 337
ISBN-13: 1420091549
DOWNLOAD EBOOKTo harness the high-throughput potential of DNA microarray technology, it is crucial that the analysis stages of the process are decoupled from the requirements of operator assistance. Microarray Image Analysis: An Algorithmic Approach presents an automatic system for microarray image processing to make this decoupling a reality. The proposed syste
Author: Luis Rueda
Publisher: CRC Press
Published: 2018-09-03
Total Pages: 520
ISBN-13: 1351831674
DOWNLOAD EBOOKMicroarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of microarrays, the book: Describes the key stages of image processing, gridding, segmentation, compression, quantification, and normalization Features cutting-edge approaches to clustering, biclustering, and the reconstruction of regulatory networks Covers different types of microarrays such as DNA, protein, tissue, and low- and high-density oligonucleotide arrays Examines the current state of various microarray technologies, including their availability and affordability Explains how data generated by microarray experiments are analyzed to obtain meaningful biological conclusions An essential reference for academia and industry, Microarray Image and Data Analysis: Theory and Practice provides readers with valuable tools and techniques that extend to a wide range of biological studies and microarray platforms.
Author:
Publisher: Springer
Published: 2011-11-06
Total Pages: 444
ISBN-13: 9781617793745
DOWNLOAD EBOOKAuthor:
Publisher: Taylor & Francis
Published:
Total Pages: 321
ISBN-13: 1134182740
DOWNLOAD EBOOKAuthor: Jiang Xu
Publisher: Frontiers Media SA
Published: 2020-06-18
Total Pages: 239
ISBN-13: 2889637980
DOWNLOAD EBOOKHerbs and herbal products are of paramount importance for human health. To beable to guarantee safety and quality, standards and testing methods are needed.Pharmacopoeias contain quality control protocols setting the standards which arethen required by governments. The quality traits are many, including the intrinsicvariables of medicinal plant, e.g. the levels of the active compounds, and the absenceof possibly natural occurring toxic compounds. On the other hand, many qualitytraits are related to agricultural conditions and practices, or to the harvesting andpost-harvest processing. With so many variables, quality control of the end productbecomes extremely complex, time consuming and costly. To ensure the quality ofmedicinal plants for human consumption quality management -the use of “goodpractices” at each step, from seed to final product- becomes a crucial aspect. In general, quality control includes the inspection of the product’s identity, purity,and content, based on its physical, chemical or biological properties. To ensure thequality of herbal medications, criteria such as botanical quality, type of preparation,physical constants, adulteration, contaminants, chemical constituents, pesticidesresidues et al. should be examined. Meanwhile, authentication of herbs is neededto avoid possible adulteration or contaminating plants, even toxic herbs such asAristolochia species. Many of the methods are long standing, such as microscopy incombination with color reactions, but some 50 years ago chromatography developedas a major tool for both qualitative and quantitative analysis of herbal preparations.Nowadays, research is working on the improvement of these methods and on thedevelopment of novel tools. For instance, next generation sequencing and mass spectrometry imaging, areemerging as new technologies for the quality control of herbal medicines. Withthese technologies, quick testing of herbal products and of mixed herbal powderpreparations, including the testing for specific plant parts (botanical drugs), can beachieved. Also, novel chemical tools such as metabolomics and Near Infrared Red(NIR) spectroscopy are being developed as powerful tools to identify and to linkthese with activity by using chemometric tools such as multivariate analysis. Finally,progress of informatic tools such as machine learning helps to deal with the big datagenerated by sequencing or mass spectrometry. However, these new technologies,like all other new born technologies, should be tested and perfected for a broaderrange of products.
Author: Yann Chevolot
Publisher: Humana Press
Published: 2011-11-09
Total Pages: 427
ISBN-13: 9781617793721
DOWNLOAD EBOOKCarbohydrate microarrays emerged as a key technology for the deciphering of the glycospace by providing a multiplex technology where tens to hundreds of carbohydrates/protein interactions can be probed in parallel. Carbohydrate Microarrays: Methods and Protocols aims to give the reader the theoretical and experimental clues necessary for the fabrication and implementation of carbohydrate microarrays. This requires three essential steps: 1) to obtain the carbohydrate probes (monosacharides, oligosacchrides, polysacchairdes, glycoconjugates or glycoclusters), 2) to immobilize these probes, and 3) to implement the protocols for biological/biochemical interaction with the desired target. This volume gives an overview of carbohydrate microarray and carbohydrate chemistry and illustrates different detection techniques and their applications. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Carbohydrate Microarrays: Methods and Protocols compiles a catalogue of protocols on carbohydrate microarrays to span the needs of researchers around the globe.
Author:
Publisher:
Published: 2004
Total Pages: 2098
ISBN-13:
DOWNLOAD EBOOKVols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author: Sabine Szunerits
Publisher: CRC Press
Published: 2015-03-24
Total Pages: 374
ISBN-13: 9814613134
DOWNLOAD EBOOKPlasmonics is a highly dynamic field, and a number of researchers and scientists from other disciplines have become involved in it. This book presents the most widely employed approaches to plasmonics and the numerous applications associated with it. There are several underlying elements in plasmonics research. Advances in nanoscience and nanotechn