In Vivo Optical Imaging of Brain Function, Second Edition

In Vivo Optical Imaging of Brain Function, Second Edition

Author: Ron D. Frostig

Publisher: CRC Press

Published: 2009-05-06

Total Pages: 0

ISBN-13: 9781420076844

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These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.


Guide to Research Techniques in Neuroscience

Guide to Research Techniques in Neuroscience

Author: Matt Carter

Publisher: Academic Press

Published: 2022-03-26

Total Pages: 416

ISBN-13: 0323915612

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Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step


Neurophotonics and Brain Mapping

Neurophotonics and Brain Mapping

Author: Yu Chen

Publisher: CRC Press

Published: 2021-03-30

Total Pages: 563

ISBN-13: 9780367657932

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Understanding how the brain works and developing effective therapeutics are important in advancing neuroscience and improving clinical patient care. Neurophotonics and Brain Mapping covers state-of-the-art research and development in optical technologies and applications for brain mapping and therapeutics. It provides a comprehensive overview of various methods developed using light, both microscopic and macroscopic techniques. Recent developments in minimally-invasive endoscopic imaging of deep brain structure and function, as well as light-based therapy are also reviewed.


Reductionism in Art and Brain Science

Reductionism in Art and Brain Science

Author: Eric R. Kandel

Publisher: Columbia University Press

Published: 2016-08-30

Total Pages: 237

ISBN-13: 0231542089

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Are art and science separated by an unbridgeable divide? Can they find common ground? In this new book, neuroscientist Eric R. Kandel, whose remarkable scientific career and deep interest in art give him a unique perspective, demonstrates how science can inform the way we experience a work of art and seek to understand its meaning. Kandel illustrates how reductionism—the distillation of larger scientific or aesthetic concepts into smaller, more tractable components—has been used by scientists and artists alike to pursue their respective truths. He draws on his Nobel Prize-winning work revealing the neurobiological underpinnings of learning and memory in sea slugs to shed light on the complex workings of the mental processes of higher animals. In Reductionism in Art and Brain Science, Kandel shows how this radically reductionist approach, applied to the most complex puzzle of our time—the brain—has been employed by modern artists who distill their subjective world into color, form, and light. Kandel demonstrates through bottom-up sensory and top-down cognitive functions how science can explore the complexities of human perception and help us to perceive, appreciate, and understand great works of art. At the heart of the book is an elegant elucidation of the contribution of reductionism to the evolution of modern art and its role in a monumental shift in artistic perspective. Reductionism steered the transition from figurative art to the first explorations of abstract art reflected in the works of Turner, Monet, Kandinsky, Schoenberg, and Mondrian. Kandel explains how, in the postwar era, Pollock, de Kooning, Rothko, Louis, Turrell, and Flavin used a reductionist approach to arrive at their abstract expressionism and how Katz, Warhol, Close, and Sandback built upon the advances of the New York School to reimagine figurative and minimal art. Featuring captivating drawings of the brain alongside full-color reproductions of modern art masterpieces, this book draws out the common concerns of science and art and how they illuminate each other.


Basic Electrophysiological Methods

Basic Electrophysiological Methods

Author: Ellen Covey

Publisher: Oxford University Press

Published: 2015-02-25

Total Pages: 241

ISBN-13: 0199342547

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Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.


Optical Brain–Computer Interface

Optical Brain–Computer Interface

Author: Dechuan Sun

Publisher: CRC Press

Published: 2024-10-03

Total Pages: 119

ISBN-13: 1040260519

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In this shortform book, Sun, French, and Unnithan explore state-of-the-art optical recording techniques, with a focus on the revolutionary miniaturized fluorescence microscope – the miniscope – for real-time and in vivo monitoring of multi-neuronal dynamics during cognition-related events. The miniscope is a powerful tool that allows real-time in vivo optical recording of multi-neuronal activity in freely moving animals. This book highlights the use of the miniscope in the context of the hippocampus, a brain region crucial for memory and cognition. The authors employ a combination of theoretical concepts, practical applications, and illustrative case studies to deliver a comprehensive understanding of optical recording techniques. They provide step-by-step guides for using the miniscope, offer insights into data analysis, and discuss its implications in the context of hippocampal research and brain–computer interfaces. Readers will gain profound insights into the role of the hippocampus in memory and cognition, and expert knowledge of the latest miniaturized in vivo optical recording techniques. The book provides them with thorough guidance on implementing a miniaturized fluorescence microscope for a brain–computer interface and information on advanced analysis techniques on the activity of large neuronal populations. This book provides an invaluable short and accessible guide for researchers, neuroscientists, and brain–computer interface enthusiasts to enable them to understand and leverage the immense potential of this advanced optical recording methodology.


The Brain-eye

The Brain-eye

Author: Éric Alliez

Publisher: Rowman & Littlefield Publishers

Published: 2016

Total Pages: 0

ISBN-13: 9781783480685

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English-language translation of a major work by French philosopher Eric Alliez, in which he offers a new perspective on critical problems in modern aesthetics.


In Vivo Optical Imaging of Brain Function

In Vivo Optical Imaging of Brain Function

Author: Ron Frostig

Publisher: CRC Press

Published: 2002-05-15

Total Pages: 293

ISBN-13: 1420038494

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The major advantage of in vivo optical techniques is the ability to study many levels of function of the CNS that are inaccessible by other methods. This rapidly expanding field is multidisciplinary in nature and findings have thus far been scattered throughout the literature. In Vivo Optical Imaging of Brain Function reviews the wide varie