Optical Polarization in Biomedical Applications
Optical Polarization in Biomedical Applications

Author: Valery V. Tuchin

Publisher: Springer Science & Business Media

Published: 2006-10-12

Total Pages: 281

ISBN-13: 3540453210

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Optical Polarization in Biomedical Applications introduces key developments in optical polarization methods for quantitative studies of tissues, while presenting the theory of polarization transfer in a random medium as a basis for the quantitative description of polarized light interaction with tissues. This theory uses the modified transfer equation for Stokes parameters and predicts the polarization structure of multiple scattered optical fields. The backscattering polarization matrices (Jones matrix and Mueller matrix) important for noninvasive medical diagnostic are introduced. The text also describes a number of diagnostic techniques such as CW polarization imaging and spectroscopy, polarization microscopy and cytometry. As a new tool for medical diagnosis, optical coherent polarization tomography is analyzed. The monograph also covers a range of biomedical applications, among them cataract and glaucoma diagnostics, glucose sensing, and the detection of bacteria.

Polarized Light in Biomedical Imaging and Sensing
Polarized Light in Biomedical Imaging and Sensing

Author: Jessica C. Ramella-Roman

Publisher: Springer Nature

Published: 2022-11-14

Total Pages: 362

ISBN-13: 3031047419

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This book focuses on biomedical applications of polarized light, covering instrumentation and modeling specific to the field. This will be the first book, written by leading researchers in the field, to tackle this important topic. Readers will learn the fundamentals of polarized light transport and how to develop instrumentation for clinical and preclinical studies. They will also become familiar with the latest advancement in data analysis and image processing for a variety of medical applications. The book is dedicated specifically to the biomedical community, including scientists, engineers, and physicians working on the development of instrumentation for clinical and preclinical use. Emphasizes biomedical imaging and sensing; Describes new computational approaches with examples; Provides detailed descriptions of novel instrumentation.

Optical Polarimetric Modalities for Biomedical Research
Optical Polarimetric Modalities for Biomedical Research

Author: Nirmal Mazumder

Publisher: Springer Nature

Published: 2023-07-25

Total Pages: 455

ISBN-13: 3031318528

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This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.

Polarized Light and Optical Systems
Polarized Light and Optical Systems

Author: Russell Chipman

Publisher: CRC Press

Published: 2018-07-16

Total Pages: 1037

ISBN-13: 1498700578

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Polarized Light and Optical Systems presents polarization optics for undergraduate and graduate students in a way which makes classroom teaching relevant to current issues in optical engineering. This curriculum has been developed and refined for a decade and a half at the University of Arizona’s College of Optical Sciences. Polarized Light and Optical Systems provides a reference for the optical engineer and optical designer in issues related to building polarimeters, designing displays, and polarization critical optical systems. The central theme of Polarized Light and Optical Systems is a unifying treatment of polarization elements as optical elements and optical elements as polarization elements. Key Features Comprehensive presentation of Jones calculus and Mueller calculus with tables and derivations of the Jones and Mueller matrices for polarization elements and polarization effects Classroom-appropriate presentations of polarization of birefringent materials, thin films, stress birefringence, crystal polarizers, liquid crystals, and gratings Discussion of the many forms of polarimeters, their trade-offs, data reduction methods, and polarization artifacts Exposition of the polarization ray tracing calculus to integrate polarization with ray tracing Explanation of the sources of polarization aberrations in optical systems and the functional forms of these polarization aberrations Problem sets to build students’ problem-solving capabilities.

Tissue Optics
Tissue Optics

Author: Valery Tuchin

Publisher:

Published: 2015

Total Pages: 988

ISBN-13: 9781628415162

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This third edition of the biomedical optics classic Tissue Optics covers the continued intensive growth in tissue optics—in particular, the field of tissue diagnostics and imaging—that has occurred since 2007. As in the first two editions, Part I describes fundamentals and basic research, and Part II presents instrumentation and medical applications. However, for the reader’s convenience, this third edition has been reorganized into 14 chapters instead of 9. The chapters covering optical coherence tomography, digital holography and interferometry, controlling optical properties of tissues, nonlinear spectroscopy, and imaging have all been substantially updated. The book is intended for researchers, teachers, and graduate and undergraduate students specializing in the physics of living systems, biomedical optics and biophotonics, laser biophysics, and applications of lasers in biomedicine. It can also be used as a textbook for courses in medical physics, medical engineering, and medical biology.

Optical Coherence Tomography
Optical Coherence Tomography

Author: Wolfgang Drexler

Publisher: Springer Science & Business Media

Published: 2008-12-10

Total Pages: 1346

ISBN-13: 3540775501

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Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.

Handbook of Biomedical Optics
Handbook of Biomedical Optics

Author: David A. Boas

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 816

ISBN-13: 1420090372

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Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamental

Coherent-Domain Optical Methods
Coherent-Domain Optical Methods

Author: Valery V. Tuchin

Publisher: Springer Science & Business Media

Published: 2004-10-15

Total Pages: 963

ISBN-13: 1402075766

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For the first time in one set of books, coherent-domain optical methods are discussed in the framework of various applications, which are characterized by a strong light scattering. A few chapters describe basic research containing the updated results on coherent and polarized light non-destructive interactions with a scattering medium, in particular, diffraction, interference, and speckle formation at multiple scattering. These chapters allow for understanding coherent-domain diagnostic techniques presented in later chapters. A large portion of Volume I is dedicated to analysis of various aspects of optical coherence tomography (OCT) - a very new and growing field of coherent optics. Two chapters on laser scanning confocal microscopy give insight to recent extraordinary results on in vivo imaging and compare the possibilities and achievements of confocol, excitation multiphoton, and OCT microscopy. This two volume reference contains descriptions of holography, interferometry and optical heterodyning techniques in their application for diagnostics of turbid materials. The most prospective methods of coherent and polarization optical imaging and spectroscopy, including polarization-sensitive optical coherent tomography, polarization diffusion wave spectroscopy, and elastic and quasi-elastic light scattering spectroscopies and image techniques, are presented.

Biomedical Optical Phase Microscopy and Nanoscopy
Biomedical Optical Phase Microscopy and Nanoscopy

Author: Natan T. Shaked

Publisher: Academic Press

Published: 2012-11-05

Total Pages: 428

ISBN-13: 0124158714

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Written by leading optical phase microscopy experts, this book is a comprehensive reference to phase microscopy and nanoscopy techniques for biomedical applications, including differential interference contrast (DIC) microscopy, phase contrast microscopy, digital holographic microscopy, optical coherence tomography, tomographic phase microscopy, spectral-domain phase detection, and nanoparticle usage for phase nanoscopy The Editors show biomedical and optical engineers how to use phase microscopy for visualizing unstained specimens, and support the theoretical coverage with applied content and examples on designing systems and interpreting results in bio- and nanoscience applications. Provides a comprehensive overview of the principles and techniques of optical phase microscopy and nanoscopy with biomedical applications. Tips/advice on building systems and working with advanced imaging biomedical techniques, including interpretation of phase images, and techniques for quantitative analysis based on phase microscopy. Interdisciplinary approach that combines optical engineering, nanotechnology, biology and medical aspects of this topic. Each chapter includes practical implementations and worked examples.

Biomedical Optical Imaging Technologies
Biomedical Optical Imaging Technologies

Author: Rongguang Liang

Publisher: Springer Science & Business Media

Published: 2012-09-21

Total Pages: 391

ISBN-13: 3642283918

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This book provides an introduction to design of biomedical optical imaging technologies and their applications. The main topics include: fluorescence imaging, confocal imaging, micro-endoscope, polarization imaging, hyperspectral imaging, OCT imaging, multimodal imaging and spectroscopic systems. Each chapter is written by the world leaders of the respective fields, and will cover: principles and limitations of optical imaging technology, system design and practical implementation for one or two specific applications, including design guidelines, system configuration, optical design, component requirements and selection, system optimization and design examples, recent advances and applications in biomedical researches and clinical imaging. This book serves as a reference for students and researchers in optics and biomedical engineering.