This book provides an introduction to design of biomedical optical imaging technologies and their applications. The main topics include: fluorescence imaging, confocal imaging, micro-endoscope, polarization imaging, hyperspectral imaging, OCT imaging, multimodal imaging and spectroscopic systems. Each chapter is written by the world leaders of the respective fields, and will cover: principles and limitations of optical imaging technology, system design and practical implementation for one or two specific applications, including design guidelines, system configuration, optical design, component requirements and selection, system optimization and design examples, recent advances and applications in biomedical researches and clinical imaging. This book serves as a reference for students and researchers in optics and biomedical engineering.
This comprehensive and self-contained text for researchers and professionals presents a detailed account of optical imaging from the viewpoint of both ray and wave optics.
This work is concerned with optical imaging – from simple apertures to complex imaging systems. It spans the range all the way from optical physics to technical optics. For microscopists and photographers it conveys a deeper insight into the intricacies of their daily used devices. Physics and engineering students learn to understand different imaging systems and sensors as well as lenses and errors, image amplification and processing. This introduction into the topic is suitable for beginners and experienced people. It is illustrated by many practical examples and may also be used as a work of reference. The book is useful for everyone employing and assessing imaging systems in general. A special focus is given to photo camera systems.
Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.
This text draws together the fields of optical microscopy and optical data storage, in a unique compilation of valuable and novel scientific work that is scarcely to be found elsewhere. The contributing authors are unquestioned leaders of their respective fields.
Optical Devices in Ophthalmology and Optometry Medical technology is a fast growing field. Optical Devices in Ophthalmology and Optometry gives a comprehensive review of modern optical technologies in ophthalmology and optometry alongside their clinical deployment. It bridges the technology and clinical domains and will be suitable in both technical and clinical environments. The book introduces and develops basic physical methods (in optics, photonics, and metrology) and their applications in the design of optical systems for use in ophthalmic medical technology. Medical applications described in detail demonstrate the advantage of utilizing optical-photonic methods. Exercises and solutions for each chapter help understand and apply basic principles and methods. From the contents: Structure and Function of the Human Eye Optics of the Human Eye Visual Disorders and Major Eye Diseases Introduction to Ophthalmic Diagnosis and Imaging Determination of the Refractive Status of the Eye Optical Visualization, Imaging, and Structural Analysis Optical Coherence Methods for Three-Dimensional Visualization and Structural Analysis Functional Diagnostics Laser???Tissue Interaction Laser Systems for Treatment of Eye Diseases and Refractive Errors
This open access book gives a complete and comprehensive introduction to the fields of medical imaging systems, as designed for a broad range of applications. The authors of the book first explain the foundations of system theory and image processing, before highlighting several modalities in a dedicated chapter. The initial focus is on modalities that are closely related to traditional camera systems such as endoscopy and microscopy. This is followed by more complex image formation processes: magnetic resonance imaging, X-ray projection imaging, computed tomography, X-ray phase-contrast imaging, nuclear imaging, ultrasound, and optical coherence tomography.
The use of optical methodology, instrumentation and photonics devices for imaging, vision and optical sensing is of increasing importance in understanding our marine environment. Subsea optics can make an important contribution to the protection and sustainable management of ocean resources and contribute to monitoring the response of marine systems to climate change. This important book provides an authoritative review of key principles, technologies and their applications.The book is divided into three parts. The first part provides a general introduction to the key concepts in subsea optics and imaging, imaging technologies and the development of ocean optics and colour analysis. Part two reviews the use of subsea optics in environmental analysis. An introduction to the concepts of underwater light fields is followed by an overview of coloured dissolved organic matter (CDOM) and an assessment of nutrients in the water column. This section concludes with discussions of the properties of subsea bioluminescence, harmful algal blooms and their impact and finally an outline of optical techniques for studying suspended sediments, turbulence and mixing in the marine environment. Part three reviews subsea optical systems technologies. A general overview of imaging and visualisation using conventional photography and video leads onto advanced techniques like digital holography, laser line-scanning and range-gated imaging as well as their use in controlled observation platforms or global observation networks. This section also outlines techniques like Raman spectroscopy, hyperspectral sensing and imaging, laser Doppler anemometry (LDA) and particle image velocimetry (PIV), optical fibre sensing and LIDAR systems. Finally, a chapter on fluorescence methodologies brings the volume to a close.With its distinguished editor and international team of contributors, Subsea optics and imaging is a standard reference for those researching, developing and using subsea optical technologies as well as environmental scientists and agencies concerned with monitoring the marine environment. - Provides an authoritative review of key principles, technologies and their applications - Outlines the key concepts in subsea optics and imaging, imaging technologies and the development of ocean optics and colour analysis - Reviews the properties of subsea bioluminescence, harmful algal blooms and their impact
Optical Imaging Devices: New Technologies and Applications delivers a comprehensive introduction to optical imaging and sensing, from devices to system-level applications. Drawing upon the extensive academic and industrial experience of its prestigious editors and renowned chapter authors, this authoritative text: Explains the physical principles of optical imaging and sensing Covers topics such as silicon-based imaging characteristics, nanophotonic phased arrays, thin-film sensors, label-free DNA sensors, and in vivo flow cytometry Presents the contributions of leading researchers, real-world examples from biomedicine, recommendations for further reading, and all measurements in SI units Optical Imaging Devices: New Technologies and Applications provides an essential understanding of the design, operation, and practical applications of optical imaging and sensing systems, making it a handy reference for students and practitioners alike.
