Medications for Opioid Use Disorder Save Lives

Medications for Opioid Use Disorder Save Lives

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2019-06-16

Total Pages: 175

ISBN-13: 0309486483

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The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.


Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-09-28

Total Pages: 483

ISBN-13: 0309459575

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Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.


Drug Addiction and Drug Policy

Drug Addiction and Drug Policy

Author: William N. Brownsberger

Publisher: Harvard University Press

Published: 2009-06-30

Total Pages: 284

ISBN-13: 0674038622

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This book is the culmination of five years of debate among distinguished scholars in law, public policy, medicine, and biopsychology, about the most difficult questions in drug policy and the study of addictions. Do drug addicts have an illness, or is the addiction under their control? Should they be treated as patients or as criminals? Challenging the conventional wisdom, the authors show that these standard dichotomies are false.


Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence

Guidelines for the Psychosocially Assisted Pharmacological Treatment of Opioid Dependence

Author: World Health Organization. Department of Mental Health and Substance Abuse

Publisher: World Health Organization

Published: 2009

Total Pages: 133

ISBN-13: 9241547545

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"These guidelines were produced by the World Health Organization (WHO), Department of Mental Health and Substance Abuse, in collaboration with the United Nations Office on Drugs and Crime (UNODC) a Guidelines Development Group of technical experts, and in consultation with the International Narcotics Control Board (INCB) secretariat and other WHO departments. WHO also wishes to acknowledge the financial contribution of UNODC and the Joint United Nations Programme on HIV/AIDS (UNAIDS) to this project. " - p. iv


The Making of Addiction

The Making of Addiction

Author: Louise Foxcroft

Publisher: Routledge

Published: 2016-03-03

Total Pages: 208

ISBN-13: 1317024826

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What does drug addiction mean to us? What did it mean to others in the past? And how are these meanings connected? In modern society the idea of drug addiction is a given and commonly understood concept, yet this was not always the case in the past. This book uncovers the original influences that shaped the creation and the various interpretations of addiction as a disease, and of addiction to opiates in particular. It delves into the treatments, regimes, and prejudices that surrounded the condition, a newly emerging pathological entity and a form of 'moral insanity' during the nineteenth century. The source material for this book is rich and surprising. Letters and diaries provide the most moving material, detailing personal struggles with addiction and the trials of those who cared and despaired. Confessions of shame, deceit, misery and terror sit alongside those of deep sensual pleasure, visionary manifestations and blissful freedom from care. The reader can follow the lifelong opium careers of literary figures, artists and politicians, glimpse a raw underworld of hidden drug use, or see the bleakness of urban and rural poverty alleviated by daily doses of opium. Delving into diaries, letters and confessions this book exposes the medical case histories and the physician's mad, lazy, commercial, contemptuous, desperate, altruistic and frustrated attempts to deal with drug addiction. It demonstrates that many of the stigmatising prejudices arose from false 'facts' and semi-mythical beliefs and thus has significant implications, not only for the history of addiction, but also for how we view the condition today.


American Overdose

American Overdose

Author: Chris McGreal

Publisher: PublicAffairs

Published: 2018-11-13

Total Pages: 346

ISBN-13: 1541773772

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A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.


Addiction Neuroethics

Addiction Neuroethics

Author: Adrian Carter

Publisher: Academic Press

Published: 2011-10-04

Total Pages: 347

ISBN-13: 0123859743

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Research increasingly suggests that addiction has a genetic and neurobiological basis, but efforts to translate research into effective clinical treatments and social policy needs to be informed by careful ethical analyses of the personal and social implications. Scientists and policy makers alike must consider possible unintended negative consequences of neuroscience research so that the promise of reducing the burden and incidence of addiction can be fully realized and new advances translated into clinically meaningful and effective treatments. This volume brings together leading addiction researchers and practitioners with neuroethicists and social scientists to specifically discuss the ethical, philosophical, legal and social implications of neuroscience research of addiction, as well as its translation into effective, economical and appropriate policy and treatments. Chapters explore the history of ideas about addiction, the neuroscience of drug use and addiction, prevention and treatment of addiction, the moral implications of addiction neuroscience, legal issues and human rights, research ethics, and public policy. - Features outstanding and truly international scholarship, with chapters written by leading experts in neuroscience, addiction medicine, psychology and more - Informs psychologists of related research in neuroscience and vice versa, giving researchers easy one-stop access to knowledge outside their area of specialty


Facing Addiction in America

Facing Addiction in America

Author: Office of the Surgeon General

Publisher: Createspace Independent Publishing Platform

Published: 2017-08-15

Total Pages: 420

ISBN-13: 9781974580620

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All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.


The American Disease

The American Disease

Author: David F. Musto

Publisher: Oxford University Press, USA

Published: 1999

Total Pages: 431

ISBN-13: 0195125096

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The American Disease is a classic study of the development of drug laws in the United States. Supporting the theory that Americans' attitudes toward drugs have followed a cyclic pattern of tolerance and restraint, author David F. Musto examines the relationz between public outcry and the creation of prohibitive drug laws from the end of the Civil War up to the present. Originally published in 1973, and then in an expanded edition in 1987, this third edition contains a new chapter and preface that both address the renewed debate on policy and drug legislation from the end of the Reagan administration to the current Clinton administration. Here, Musto thoroughly investigates how our nation has dealt with such issues as the controversies over prevention programs and mandatory minimum sentencing, the catastrophe of the crack epidemic, the fear of a heroin revival, and the continued debate over the legalization of marijuana.