OECD Guidelines for the Testing of Chemicals / Section 3: Degradation and Accumulation Revised Introduction to the OECD Guidelines for Testing of Chemicals, Section 3
OECD Guidelines for the Testing of Chemicals / Section 3: Degradation and Accumulation Revised Introduction to the OECD Guidelines for Testing of Chemicals, Section 3

Author: OECD

Publisher: OECD Publishing

Published: 2006-09-11

Total Pages: 17

ISBN-13: 9264030212

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The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers environmental fate and behaviour. In 2017, the section 3 "Degradation and Accumulation" was renamed to " Environmental fate and behaviour" to take into account Test Guidelines measuring endpoints such as dispersion, aggregation.

Persistent, Bioaccumulative, and Toxic (PBT) Chemicals
Persistent, Bioaccumulative, and Toxic (PBT) Chemicals

Author: Adam D. K. Abelkop

Publisher: CRC Press

Published: 2018-10-08

Total Pages: 288

ISBN-13: 1482298783

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Developed from the efforts of a multiyear, international project examining how persistent, bioaccumulative, and toxic (PBT) chemicals are evaluated and managed, Persistent, Bioaccumulative, and Toxic (PBT) Chemicals: Technical Aspects, Policies, and Practices focuses on improving the processes that govern PBTs. Incorporating science and policy literature—as well as interviews and panel discussions featuring experts from around the world—this book provides you with an international perspective of PBT policies (centering on Europe, Asia, and North America), and reveals major findings and recommendations for improving PBT science, laws, and policies. It includes case studies of specific chemicals, provides an introduction to the overall subject of toxic chemicals, and weighs in on science and policy expansion for PBTs. It also provides summary tables of important PBTs, and discussions on the number of PBTs in commerce, weight of evidence approaches, market deselection, and international management. The text: Assesses the history, current practice, and future of PBT management Considers the roles scientific data, modeling, and conventions play in identifying and regulating PBTs Explores the number of PBTs in commerce and the growing role of weight of evidence (WOE) in the making of PBT determinations Identifies issues that are likely to come up in WOE judgments Examines international, national, subnational, and regional PBT policies Includes a comprehensive and easy-to-understand analysis of PBT science and policy This book reviews the current science, policies, and practices surrounding the regulation of PBTs. It also provides relevant research, recommendations, and suggestions for improving the management and oversight of PBTs.

OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319A: Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP)
OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319A: Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP)

Author: OECD

Publisher: OECD Publishing

Published: 2018-06-27

Total Pages: 41

ISBN-13: 9264303219

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The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...

The Mitigation of Marine Plastic Pollution in International Law
The Mitigation of Marine Plastic Pollution in International Law

Author: Judith Schäli

Publisher: BRILL

Published: 2022-04-19

Total Pages: 476

ISBN-13: 9004508619

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The open access publication of this book has been published with the support of the Swiss National Science Foundation. The massive accumulation of plastics in marine environments is one of the most pressing environmental concerns of our time. This book examines the relevant international legal framework applying to land-based sources of plastic pollution. Against the backdrop of the dynamics of recent policy formulation in this field, it outlines the main developments and provides a snapshot inventory of state obligations related to plastic pollution mitigation. The Mitigation of Marine Plastic Pollution in International Law identifies the main barriers and opportunities, and points out the possible building blocks of an enhanced regime.