OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Background Review of the Uterotrophic Bioassay
OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Background Review of the Uterotrophic Bioassay

Author: OECD

Publisher: OECD Publishing

Published: 2004-11-01

Total Pages: 218

ISBN-13: 9264078851

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This detailed background review paper provides a summary of the relevant literature (up to September 2001) relevant to the standardisation and validation of the rodent uterotrophic bioassay. The rodent uterotrophic bioassay is being validated as part of the OECD Test Guidelines Programme. The rodent uterotrophic bioassay is based on the principle that the uterus is under the control of oestrogens to stimulate and maintain growth. If endogenous sources of this hormone are not available, the animal will require an exogenous source to initiate and/or restore uterine growth.

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties
OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties

Author: OECD

Publisher: OECD Publishing

Published: 2007-10-15

Total Pages: 21

ISBN-13: 9264067418

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The Uterotrophic Bioassay is an in vivo short-term screening test. It is based on the increase in uterine weight or uterotrophic response. The Uterotrophic Bioassay relies for its sensitivity on an animal test system in which the ...

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Hazard Classification Systems for Specific Target Organ Systemic Toxicity Following Single or Repeated Exposure in OECD Member Countries
OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Hazard Classification Systems for Specific Target Organ Systemic Toxicity Following Single or Repeated Exposure in OECD Member Countries

Author: OECD

Publisher: OECD Publishing

Published: 2002-05-10

Total Pages: 20

ISBN-13: 9264078428

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This detailed review document examines member country hazard classification systems for specific target organ systemic toxicity following single or repeated exposure.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification in OECD Member Countries of Substances and Mixtures which cause Respiratory Tract Irritation and Corrosion
OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Detailed Review Document on Classification in OECD Member Countries of Substances and Mixtures which cause Respiratory Tract Irritation and Corrosion

Author: OECD

Publisher: OECD Publishing

Published: 2004-11-01

Total Pages: 13

ISBN-13: 9264079092

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This detailed review documents examines member country classification of substances and mixtures which cause respiratorytract irritation and corrosion.

OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Development of OECD Guidelines for Testing of Chemicals
OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Document for the Development of OECD Guidelines for Testing of Chemicals

Author: OECD

Publisher: OECD Publishing

Published: 2002-05-10

Total Pages: 28

ISBN-13: 9264077928

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This Monograph describes in detail the process of Test Guideline development, including the structure of the Test Guidelines Programme, the responsibilities of those involved and the procedures which should be followed.