Historical Aspects of Pediatric Surgery
Historical Aspects of Pediatric Surgery

Author: P. P. Rickham

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 483

ISBN-13: 3642708250

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At first sight it may appear strange that a volume of Progress in Pediatric Surgery should be devoted to the history of our specialty. One assumes that progress is concerned primarily with recent developments whilst history deals with matters of the past. However, in the past there has also been considerable progress in the development of our understand ing of paediatric surgical problems, otherwise we would not have pro gressed to our present achievements. The editors, therefore, do not apologize for compiling this volume but, on the contrary, feel that the publication of this volume is most timely. Modern paediatric surgery has now been practised for three genera tions. The handful of pioneers who were the founders of our specialty worked mainly before the last world war. A few dozen of the inter mediary generation started work immediately after the war, while the new generation who are now dominating our specialty must be counted in thousands. Two factors have radically altered paediatric surgery as practised by the intermediary and the present generation of surgeons.

The Minipig in Biomedical Research
The Minipig in Biomedical Research

Author: Peter A. McAnulty

Publisher: CRC Press

Published: 2011-12-19

Total Pages: 713

ISBN-13: 1439811180

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The Minipig in Biomedical Research is a comprehensive resource for research scientists on the potential and use of the minipig in basic and applied biomedical research, and the development of drugs and chemicals. Written by acknowledged experts in the field, and drawing on the authors’ global contacts and experience with regulatory authorities and the pharmaceutical and other industries, this accessible manual ranges widely over the biological, scientific, and practical uses of the minipig in the laboratory. Its coverage extends from the minipig’s origins, anatomy, genetics, immunology, and physiology to its welfare, health, and husbandry; practical dosing and examination procedures; surgical techniques; and all areas of toxicity testing and the uses of the minipig as a disease model. Regulatory aspects of its use are considered. The reader will find an extensive amount of theoretical and practical information in the pharmacology; ADME and toxicology chapters which will help scientists and managers when deciding which species to use in basic research; drug discovery and pharmacology; and toxicology studies of chemicals, biotechnology products and devices. The book discusses regulatory uses of minipigs in the evaluation of human and veterinary pharmaceuticals, medical devices, and other classes of xenobiotics. It describes features of normal health, normal laboratory values, and common diseases. It also carefully elucidates ethical and legal considerations in their supply, housing, and transport. The result is an all-inclusive and up to date manual about the experimental uses of the minipig that describes ‘How to’ and ‘Why’ and ’What to expect in the normal’, combining enthusiasm and experience with critical assessment of its values and potential problems.

Thymus Gland Pathology
Thymus Gland Pathology

Author: Corrado Lavini

Publisher: Springer Science & Business Media

Published: 2009-05-08

Total Pages: 274

ISBN-13: 884700828X

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The thymus is a gland that over the last two centuries has generated great awareness not only from the anatomical perspective but also for the physiological and pat- logical roles it plays in many disease processes. Prior to the early studies on its th anatomy and physiology in the 18 century, the thymus was believed to perform - usual and curious functions such as purification of the nervous system, providing a protective cushion for the vasculature of the superior mediastinum, fetal nouri- ment, or more spiritual roles such as being the seat of the soul, among others. D- th ing the 19 century important anatomical/physiological studies took place focusing on the role of the thymus in pathological conditions. However, it was not until the th middle of the 19 century that a more comprehensive analysis of the role of the thymic gland and its role in pathogenesis began to emerge. Currently, while the knowledge gained on the diverse aspects of the thymic gland has furthered our understanding of its role in a gamut of processes, more knowledge is still being sought, and by no means is a full understanding of the gland’s physi- ogy and pathology complete. Different aspects, including its purported endocrine function, its association with other autoimmune diseases like multiple sclerosis, rheumatoid arthritis, and lupus erythematosus, among others, are under evaluation and research.

Minimally Invasive Oral and Maxillofacial Surgery
Minimally Invasive Oral and Maxillofacial Surgery

Author: Oded Nahlieli

Publisher: Springer

Published: 2017-12-12

Total Pages: 208

ISBN-13: 3662545926

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Minimally invasive techniques, designed to reduce morbidity and risk while simultaneously improving outcomes, are increasingly being used in oral and maxillofacial surgery. This book covers the most recent technological developments and the advanced techniques used when performing such minimally invasive surgery in patients with common and rare oral and maxillofacial pathologies. The relevant basic science is reviewed, but the principal focus is on the surgical techniques themselves. These are described step by step with the aid of numerous superb color illustrations that will help the clinician to gain a full understanding of the technology and the procedures. In addition, still emerging techniques of endoscopy, navigation, and minimally invasive surgery are well covered. This text will be a premier resource for physicians who diagnose and treat oral and maxillofacial pathologies and injuries.