NMR with Biological Macromolecules in Solution

NMR with Biological Macromolecules in Solution

Author: Kurt Wüthrich

Publisher: World Scientific Publishing Company

Published: 2021

Total Pages: 270

ISBN-13: 9789811235788

DOWNLOAD EBOOK

The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones.Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones.


Nuclear Magnetic Resonance of Biological Macromolecules, Part A

Nuclear Magnetic Resonance of Biological Macromolecules, Part A

Author:

Publisher: Elsevier

Published: 2001-07-12

Total Pages: 513

ISBN-13: 0080496881

DOWNLOAD EBOOK

This volume and its companion, Volume 339, supplement Volumes 176, 177, 239, and 261. Chapters are written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules.


Nuclear Magnetic Resonance of Biological Macromolecules, Part C

Nuclear Magnetic Resonance of Biological Macromolecules, Part C

Author:

Publisher: Academic Press

Published: 2005-05-04

Total Pages: 670

ISBN-13: 0080549470

DOWNLOAD EBOOK

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences. Nuclear Magnetic Resonance of Biological Macromolecules, Part C is written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules.* One of the most highly respected publications in the field of biochemistry since 1955 * Frequently consulted, and praised by researchers and reviewers alike * Truly an essential publication for anyone in any field of the life sciences


Magnetic Resonance in Biological Systems

Magnetic Resonance in Biological Systems

Author: A. Ehrenberg

Publisher: Elsevier

Published: 2013-09-24

Total Pages: 441

ISBN-13: 148322676X

DOWNLOAD EBOOK

Magnetic Resonance in Biological Systems, Volume 9 is a collection of manuscripts presented at the Second International Conference on Magnetic Resonance in Biological Systems, held in Wenner-Gren Center, Stockholm, Sweden on June 1966. The conference is sponsored by International Union of Biochemistry Swedish Medical Research Council Swedish Natural Science Research Council Wenner-Gren Center Foundation for Scientific Research. This book contains 51 chapters, and begins with reviews of NMR investigations of biological macromolecules, including proteins, amino acids, and glycylglycine copper (II). Considerable chapters are devoted to numerous biological studies using the electronic paramagnetic resonance (EPR), thus introducing the branch of science called submolecular biology. This book also explores other applications of NMR and EPR, with special emphasis on blood component analysis and protein-metal complexes. The final chapters survey the principles and applications of Mössbauer spectroscopy. This book will prove useful to analytical chemists and biologists.


Nuclear Magnetic Resonance of Biological Macromolecules, Part B

Nuclear Magnetic Resonance of Biological Macromolecules, Part B

Author:

Publisher: Elsevier

Published: 2001-07-12

Total Pages: 487

ISBN-13: 008049689X

DOWNLOAD EBOOK

This volume and its companion, Volume 338, supplement Volumes 176, 177, 239, and 261. Chapters are written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules.


Biological NMR Spectroscopy

Biological NMR Spectroscopy

Author: John L. Markley

Publisher: Oxford University Press

Published: 1997-01-30

Total Pages: 375

ISBN-13: 0195094689

DOWNLOAD EBOOK

This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.


Nuclear Magnetic Resonance of Biological Macromolecules, Part A

Nuclear Magnetic Resonance of Biological Macromolecules, Part A

Author: Thomas L. James

Publisher: Academic Press

Published: 2001

Total Pages: 528

ISBN-13:

DOWNLOAD EBOOK

This volume and its companion, Volume 339, supplement Volumes 176, 177, 239, and 261. Chapters are written with a "hands-on" perspective. That is, practical applications with critical evaluations of methodologies and experimental considerations needed to design, execute, and interpret NMR experiments pertinent to biological molecules.


NMR of Macromolecules

NMR of Macromolecules

Author: Gordon C. K. Roberts

Publisher: IRL Press

Published: 1993-07-15

Total Pages: 418

ISBN-13: 9780199632244

DOWNLOAD EBOOK

Following the enormous increase in the use of nuclear magnetic resonance to study the conformations and interactions of biological macromolecules, this book provides detailed guidance on how to choose the most appropriate protocol to obtain the required information, how to carry out the experiment, and how to analyse the resulting spectra.


Nuclear Magnetic Resonance

Nuclear Magnetic Resonance

Author: G. A. Webb

Publisher: Royal Society of Chemistry

Published: 2006

Total Pages: 587

ISBN-13: 0854043578

DOWNLOAD EBOOK

As a spectroscopic method, nuclear magnetic resonance (NMR) has seen spectacular growth, both as a technique and in its applications. Today's applications of NMR span a wide range of scientific disciplines, from physics to biology to medicine. Each volume of Nuclear Magnetic Resonance comprises a combination of annual and biennial reports which together provide comprehensive coverage of the literature on this topic. This Specialist Periodical Report reflects the growing volume of published work involving NMR techniques and applications, in particular NMR of natural macromolecules, which is covered in two reports: NMR of Proteins and Nucleic Acids; and NMR of Carbohydrates, Lipids and Membranes. For those wanting to become rapidly acquainted with specific areas of NMR, Nuclear Magnetic Resonance provides unrivalled scope of coverage. Seasoned practitioners of NMR will find this an invaluable source of current methods and applications. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading experts in their specialist fields, this series is designed to help the chemistry community keep current with the latest developments in their field. Each volume in the series is published either annually or biennially and is a superb reference point for researchers. www.rsc.org/spr


NMR in Structural Biology

NMR in Structural Biology

Author: Kurt Wthrich

Publisher: World Scientific

Published: 1995

Total Pages: 770

ISBN-13: 9789810223847

DOWNLOAD EBOOK

The volume presents a survey of the research by Kurt Wthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.